Hepatitis B Virus X Protein Upregulates Intracellular Calcium Signaling by Binding C-terminal of Orail ProteinSpringer Science and Business Media LLC - Tập 38 - Trang 26-34 - 2018
Jing-hong Yao, Zi-jian Liu, Jian-hua Yi, Jun Wang, Ya-nan Liu
Hepatitis B virus X (HBx) protein plays a pivotal role in the development of hepatitis B virus (HBV)-associated hepatocellular carcinoma. Although regulation of cytosolic calcium is essential for HBV replication and is mediated by HBx protein, the mechanism of HBx protein regulating intracellular calcium level remains poorly understood. The present study examined whether HBx protein elevated the i...... hiện toàn bộ
Degrees of Diaphragma Sellae Descent during Transsphenoidal Pituitary Adenoma Resection: Predictive Factors and Effect on OutcomeSpringer Science and Business Media LLC - - 2018
Ahmed Abdelmaksoud, Peng Fu, Osamah Alwalid, Ahmed Elazab, Ahmed Zalloom, Wei Xiang, Xiao-bing Jiang, Hong-yang Zhao
This study is aimed to classify degrees of diaphragma sellae (DS) descent into sella turcica according to the surgical field block caused by the descent and to construct predictive imaging criteria for the degree of descent, and in addition, to determine whether there is any correlation between the degree of DS descent and the operative outcome (in the form of cerebrospinal fluid leak and/or prese...... hiện toàn bộ
Huai Qi Huang-induced Apoptosis via Down-regulating PRKCH and Inhibiting RAF/MEK/ERK Pathway in Ph+ Leukemia CellsSpringer Science and Business Media LLC - Tập 40 - Trang 354-362 - 2020
Wen-fu Xu, Zhu-jun Wang, Kun Li, Ya-qing Shen, Ke Lu, Xue-yan Lv, Yu-xi Wen, Run-ming Jin
Imatinib mesylate (IM) is the first-line treatment for Philadelphia (Ph) chromosomal positive leukemia by inhibiting phosphorylation of substrates via binding to the ABL kinase domain. Because of the drug resistance, side effects and the high cost of IM, it is necessary to find anti-cancer drugs with relatively low toxicity and cost, and enhanced efficacy, such as traditional Chinese medicines (TC...... hiện toàn bộ
Cupula Nhẹ: Có Hay Không Có? Dịch bởi AI Springer Science and Business Media LLC - Tập 40 - Trang 455-462 - 2020
Su-lin Zhang, E. Tian, Wen-chao Xu, Yu-ting Zhu, Wei-jia Kong
Chứng chóng mặt tư thế lành tính từng đợt (BPPV) đại diện cho hình thức phổ biến nhất của chóng mặt tư thế. Nó được gây ra bởi sự rời ra của các otoconia tự do nổi trong các ống bán khuyên (canalolithiasis) hoặc bám vào cupula (cupulolithiasis). Một loại BPPV kiểu cupulolithiasis (hoặc kiểu cupula nặng) liên quan đến ống bán khuyên bên (LSCC) thể hiện chứng nháy mắt vị trí thay đổi theo hướng khôn...... hiện toàn bộ
#BPPV #cupula nhẹ #chóng mặt tư thế #nháy mắt vị trí #cơ chế #chiến lược điều trị
Role of Neuroimmune Interactions in COVID-19-related Cardiovascular DamageSpringer Science and Business Media LLC - Tập 42 - Trang 555-560 - 2022
Xing Chen, Wei-hua Qiao, Hong Cao, Jia-wei Shi, Xin-ling Du, Nian-guo Dong
Coronavirus disease 2019 (COVID-19) has caused a global pandemic impacting over 200 countries/regions and more than 200 million patients worldwide. Among the infected patients, there is a high prevalence of COVID-19-related cardiovascular injuries. However, the specific mechanisms linking cardiovascular damage and COVID-19 remain unclear. The COVID-19 pandemic also has exacerbated the mental healt...... hiện toàn bộ