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Use of prior odds for missing persons identifications
Springer Science and Business Media LLC - Tập 2 - Trang 1-6 - 2011
Identification of missing persons from mass disasters is based on evaluation of a number of variables and observations regarding the combination of features derived from these variables. DNA typing now is playing a more prominent role in the identification of human remains, and particularly so for highly decomposed and fragmented remains. The strength of genetic associations, by either direct or k......
Contrasting signals of positive selection in genes involved in human skin-color variation from tests based on SNP scans and resequencing
Springer Science and Business Media LLC - Tập 2 - Trang 1-12 - 2011
Numerous genome-wide scans conducted by genotyping previously ascertained single-nucleotide polymorphisms (SNPs) have provided candidate signatures for positive selection in various regions of the human genome, including in genes involved in pigmentation traits. However, it is unclear how well the signatures discovered by such haplotype-based test statistics can be reproduced in tests based on ful......
Modeling the contrasting Neolithic male lineage expansions in Europe and Africa
Springer Science and Business Media LLC - Tập 4 - Trang 1-8 - 2013
Patterns of genetic variation in a population carry information about the prehistory of the population, and for the human Y chromosome an especially informative phylogenetic tree has previously been constructed from fully-sequenced chromosomes. This revealed contrasting bifurcating and starlike phylogenies for the major lineages associated with the Neolithic expansions in sub-Saharan Africa and We......
Tracing Jomon and Yayoi ancestries in Japan using ALDH2 and JC virus genotype distributions
Springer Science and Business Media LLC - Tập 6 - Trang 1-5 - 2015
According to the dual structure model, the modern Japanese ethnic population consists of a mixture of the Jomon people, who have existed in Japan since at least the New Stone Age, and the Yayoi people, who migrated to western Japan from China around the year 300 bc Some reports show that the Yayoi are linked to a mutation of the aldehyde dehydrogenase 2 gene (ALDH2). Recent viral studies indicate ......
Purification of crime scene DNA extracts using centrifugal filter devices
Springer Science and Business Media LLC - Tập 4 - Trang 1-8 - 2013
The success of forensic DNA analysis is limited by the size, quality and purity of biological evidence found at crime scenes. Sample impurities can inhibit PCR, resulting in partial or negative DNA profiles. Various DNA purification methods are applied to remove impurities, for example, employing centrifugal filter devices. However, irrespective of method, DNA purification leads to DNA loss. Here ......
Response to Grisedale and Van Daal: comparison of STR profiling from low template DNA extracts with and without the consensus profiling method
Springer Science and Business Media LLC - Tập 4 Số 1 - Trang 1 - 2013
High throughput DNA sequencing to detect differences in the subgingival plaque microbiome in elderly subjects with and without dementia
Springer Science and Business Media LLC - Tập 3 - Trang 1-12 - 2012
To investigate the potential association between oral health and cognitive function, a pilot study was conducted to evaluate high throughput DNA sequencing of the V3 region of the 16S ribosomal RNA gene for determining the relative abundance of bacterial taxa in subgingival plaque from older adults with or without dementia. Subgingival plaque samples were obtained from ten individuals at least 70 ......
Editors’ Pick: What a pain…, or not!
Springer Science and Business Media LLC - Tập 5 - Trang 1-2 - 2014
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