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Treatment of acute myelogenous leukemia in children
Springer Science and Business Media LLC - Tập 2 - Trang 17-25 - 1985
G. Schellong, U. Creutzig, J. Ritter
Progress in the treatment of childhood AML has not equalled the advances obtained in the management of ALL. Two recent chemotherapy studies (i.e. VAPA and BFM 78), however, reported marked increase in the proportion of long-term remissions. The initial therapy of the cooperative study BFM 78 consisted of two 4-week phases of intensive induction/consolidation with 7 different drugs and cranial irra...... hiện toàn bộ
Book Review
Springer Science and Business Media LLC - Tập 9 - Trang 215-215 - 1992
Peter Reizenstein
Cytological and immunological study of 139 patients with acute leukemia
Springer Science and Business Media LLC - Tập 1 Số 1 - 1984
Jun Minowada, G Mathé, Maurice Barcos, M Ginsbourg, Preisler Hd, C Canon, Peter Reizenstein
Monoclonal antibodies in the management of carcinoma patients
Springer Science and Business Media LLC - Tập 8 - Trang 223-228 - 1991
Mario Roselli, Carlo U. Casciani, Fiorella Guadagni, Oreste Buonomo, Beniamino Iorio, Alessandra Diodati, Vincenzo Vittorini, John W. Greiner, David Colcher, Jeffrey Schlom
The use of monoclonal antibodies (MAbs) in the clinical management of carcinoma patients is reported in the present review. Among the various MAbs generated, MAb B72.3 (LTIB, National Cancer Institute, U.S.A.) has been extensively used in clinical trials either for antigen identification (TAG-72) in sera, or for tumor localization in carcinoma patients. Serum assay results, in colorectal cancer pa...... hiện toàn bộ
The selection of monoclonal antibodies for tumour localization in patients with colorectal carcinoma
Springer Science and Business Media LLC - - 1984
Karol Sikora, Thomas Alderson, P. J. Finan, Edwin S. Lennox, N. I. Markham, Anne Ritson, Howard Smedley
A phase II study of sequential methotrexate and 5-fluorouracil in colorectal carcinoma
Springer Science and Business Media LLC - Tập 5 - Trang 239-241 - 1988
M. J. Harding, S. B. Kaye, M. Soukop, J. C. Ferguson
Nineteen patients with locally recurrent or metastatic colorectal carcinomas were treated with 3-weekly cycles of methotrexate (MTX) given as a loading dose of 100 mg m−2 and a subsequent 12 h infusion of 400 mg m−2, followed by 5-fluorouracil (5-FU) 900 mg m−2 as a bolus injection on completion of infusion. No objective responses were seen in 14 evaluable patients. One early death was treatment r...... hiện toàn bộ
Pharmacokinetics ofcis-dichloro-trans-dihydroxy-bis-isopropylamine platinum IV (iproplatinum, chip) in patients with normal and impaired renal function and following intraperitoneal administration
Springer Science and Business Media LLC - Tập 5 - Trang 153-158 - 1988
D. J. Kerr, M. Harding, J. G. Farmer, J. Amarin, R. G. Blackie, S. J. Harland, S. B. Kaye
CHIP is a quadrivalent platinum (Pt) complex, introduced clinically as a less toxic alternative tocis-platinum. The drug’s major route of excretion is via the kidneys, and in this study the pharmacokinetics of unchanged CHIP, filterable Pt and total Pt have been determined following intravenous administration to patients with a range of renal function. Total Pt and filterable Pt in plasma decayed ...... hiện toàn bộ
Late complications of allogeneic bone marrow transplantation
Springer Science and Business Media LLC - Tập 8 - Trang 261-263 - 1991
A. Bacigalupo, M. T. Van Lint, F. Frassoni, F. Gualandi, T. Lamparelli, A. M. Marmont
This report underlines the occurrence of multiple early and late complications after allogeneic BMT. Most of these are caused by the conditioning regimen, and especially by the use of total body irradiation. This should discourage the use of radiation for patients with non-malignant disorders such as aplastic anemia. We have shown that interstitial pneumonia is greatly reduced after fractionated T...... hiện toàn bộ
Flutamide — An antiandrogen inhibiting prostatic cancer and prostatic secretion with retention of potency
Springer Science and Business Media LLC - Tập 5 - Trang 61-65 - 1988
B. Stegmayr, J. E. Johansson, L. B. Schnürer
Ten men with prostatic cancer, stage T3M0 Nx or more, who were anxious to maintain sexual potency, were treated with flutamide. The eight metastasis-free tumours remained stable during treatment periods of 3–48 months. The two tumours with metastasis at the start of treatment showed growth inhibition for 3 and 7 months, respectively, but thereafter progressed, leacling to change of treatment. Nine...... hiện toàn bộ
C-Reactive protein during chemotherapy for acute leukemia with special reference to non-infective causes of fever
Springer Science and Business Media LLC - Tập 3 - Trang 71-75 - 1986
Sven Grützmeier, Henning Von Schenck
C-reactive protein, CRP, was followed longitudinally in 41 patients being treated for acute leukemia. It was analysed by a rapid (2-h) immunochemical assay in a laser-nephelometer. The, cytostatic treatment given either intravenously or intrathecally did not cause any CRP increase with the exception of 7% of the treatment courses, given to 3 patients, and neither did transfusion reactions. The pat...... hiện toàn bộ
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