Excitatory afferent modulation of complex spike synchronySpringer Science and Business Media LLC - Tập 2 - Trang 165-170 - 2003
Eric J. Lang
Inferior olivary neurons receive extensive glutamatergic and GABAergic innervation. Yet, because of the membrane properties of olivary neurons these neurotransmitters can produce only small changes in the firing rates of these cells. Moreover, olivary neurons can generate spontaneous spike activity in the absence of excitatory glutamatergic input. These facts suggest that glutamate and GABA have a...... hiện toàn bộ
Smaller Cerebellar Lobule VIIb is Associated with Tremor Severity in Parkinson’s DiseaseSpringer Science and Business Media LLC - - Trang 1-8 - 2023
Fatemeh Sadeghi, Monika Pötter-Nerger, Kai Grimm, Christian Gerloff, Robert Schulz, Simone Zittel
Alterations
in the cerebellum’s morphology in Parkinson’s disease (PD) point to its pathophysiological involvement in this movement disorder. Such abnormalities have previously been attributed to different PD motor subtypes. The aim of the study was to relate volumes of specific cerebellar lobules to motor symptom severity, in particular tremor (TR), bradykinesia/rigidity (BR), and postural insta...... hiện toàn bộ
ErratumSpringer Science and Business Media LLC - Tập 2 - Trang 80-80 - 2003
Piergiorgio Strata
Modulation of NMDA receptors in the cerebellum. 1. Properties of the NMDA receptor that modulate its functionSpringer Science and Business Media LLC - Tập 4 - Trang 154-161 - 2005
Marta Llansola, Ana Sanchez-Perez, Omar Cauli, Vicente Felipo
NMDA receptors modulate important cerebral processes such as synaptic plasticity, long-term potentiation, learning and memory, etc. NMDA receptors in cerebellum have specific characteristics that make their function and modulation different from those of NMDA receptors in other brain areas. In this and the accompanying review we summarize the information available on the modulation of NMDA recepto...... hiện toàn bộ
Pogo: A Novel Spontaneous Ataxic Mutant MouseSpringer Science and Business Media LLC - Tập 8 - Trang 155-162 - 2009
Nam-Seob Lee, Young-Gil Jeong
The Pogo (pogo/pogo) mouse is a naturally occurring neurological mutant from a Korean wild-type mouse characterized by loss of balance and motor coordination due to dysfunction of the cerebellum. The Pogo mutation is believed to be an allele of P/Q-type calcium channel mutants such as tottering, leaner, and rolling mouse Nagoya. These mutants have been served as mouse models for a group of neurode...... hiện toàn bộ
Ceramide in primary astrocytes from cerebellum: metabolism and role in cell proliferationSpringer Science and Business Media LLC - Tập 1 - Trang 129-135 - 2002
Laura Riboni, Guido Tettamanti, Paola Viani
Cerebellar astrocytes are equipped with an efficient molecular machinery able to control the levels, and possibly the subcellular location, of ceramide. The major metabolic routes that contribute to the maintenance and variation of the cellular ceramide include ceramide biosynthesis, byde novo pathway or sphingosine recycling, ceramide formation from complex sphingolipids degradation and ceramide ...... hiện toàn bộ