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Comprehensive molecular, genomic and phenotypic analysis of a major clone of Enterococcus faecalis MLST ST40
Springer Science and Business Media LLC - Tập 16 - Trang 1-20 - 2015
Enterococcus faecalis is a multifaceted microorganism known to act as a
beneficial intestinal commensal bacterium. It is also a dreaded nosocomial
pathogen causing life-threatening infections in hospitalised patients. Isolates
of a distinct MLST type ST40 represent the most frequent strain type of this
species, distributed worldwide and originating from various sources (animal,
human, environmenta...
Genomic features and computational identification of human microRNAs under long-range developmental regulation
Springer Science and Business Media LLC - Tập 12 Số 1 - 2011
A bioinformatic survey of RNA-binding proteins in Plasmodium
Springer Science and Business Media LLC - Tập 16 - Trang 1-26 - 2015
The malaria parasites in the genus Plasmodium have a very complicated life cycle
involving an invertebrate vector and a vertebrate host. RNA-binding proteins
(RBPs) are critical factors involved in every aspect of the development of these
parasites. However, very few RBPs have been functionally characterized to date
in the human parasite Plasmodium falciparum. Using different bioinformatic
methods...
Recent CR1 non-LTR retrotransposon activity in coscoroba reveals an insertion site preference
Springer Science and Business Media LLC - Tập 9 - Trang 1-6 - 2008
Chicken repeat 1 (CR1) is a taxonomically widespread non-LTR retrotransposon.
Insertion site bias, or lack thereof, has not been demonstrated for CR1. Recent
CR1 retrotranspositions were used to examine flanking regions for GC content and
nucleotide bias at the insertion site. Elucidation of the exact octomer repeat
sequence (TTCTGTGA) allowed for the identification of younger insertion events.
Th...
Generation and analysis of expressed sequence tags from six developing xylem libraries in Pinus radiata D. Don
Springer Science and Business Media LLC - - 2009
Abstract Background Wood is a major renewable natural resource for the timber,
fibre and bioenergy industry. Pinus radiata D. Don is the most important
commercial plantation tree species in Australia and several other countries;
however, genomic resources for this species are very limited in public
databases. Our primary objective was to sequence a large number of expressed
sequence tags (ESTs) fr...
Resilience, plasticity and robustness in gene expression during aging in the brain of outbred deer mice
Springer Science and Business Media LLC - Tập 22 - Trang 1-10 - 2021
Genes that belong to the same network are frequently co-expressed, but
collectively, how the coordination of the whole transcriptome is perturbed
during aging remains unclear. To explore this, we calculated the correlation of
each gene in the transcriptome with every other, in the brain of young and older
outbred deer mice (P. leucopus and P. maniculatus). In about 25 % of the genes,
coordination ...
Gene expression profile of rat left ventricles reveals persisting changes following chronic mild exercise protocol: implications for cardioprotection
Springer Science and Business Media LLC - Tập 10 - Trang 1-13 - 2009
Epidemiological studies showed that physical exercise, specifically moderate
lifelong training, is protective against cardiovascular morbidity and mortality.
Most experimental work has focused into the effects and molecular mechanisms
underlying intense, rather than mild exercise, by exploring the acute effect of
training. Our study aims at investigating the cardioprotective effect of mild
chronic...
Interaction between Rag genes results in a unique synergistic transcriptional response that enhances soybean resistance to soybean aphids
Springer Science and Business Media LLC - - 2021
Abstract Background Pyramiding different resistance genes into one plant
genotype confers enhanced resistance at the phenotypic level, but the molecular
mechanisms underlying this effect are not well-understood. In soybean, aphid
resistance is conferred by Rag genes. We compared the transcriptional response
of four soybean genotypes to aphid feeding to assess how the combination of Rag
genes enhan...
Anti-masculinization induced by aromatase inhibitors in adult female zebrafish
Springer Science and Business Media LLC - Tập 21 - Trang 1-10 - 2020
Early sex differentiation genes of zebrafish remain an unsolved mystery due to
the difficulty to distinguish the sex of juvenile zebrafish. However, aromatase
inhibitors (AIs) could direct juvenile zebrafish sex differentiation to male and
even induce ovary-to-testis reversal in adult zebrafish. In order to determine
the transcriptomic changes of sex differentiation in juvenile zebrafish and
early...
A novel method to identify gene interaction patterns
Springer Science and Business Media LLC - Tập 22 - Trang 1-15 - 2021
Gene interaction patterns, including modules and motifs, can be used to identify
cancer specific biomarkers and to reveal the mechanism of tumorigenesis. Most of
the existing module network inferencing methods focus on gene independent
functional patterns, while the studies of overlapping characteristics between
modules are lacking. The objective of this study was to reveal the functional
overlapp...
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