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Comprehensive molecular, genomic and phenotypic analysis of a major clone of Enterococcus faecalis MLST ST40
Springer Science and Business Media LLC - Tập 16 - Trang 1-20 - 2015
Melanie Zischka, Carsten T Künne, Jochen Blom, Dominique Wobser, Türkân Sakιnç, Kerstin Schmidt-Hohagen, P Wojtek Dabrowski, Andreas Nitsche, Johannes Hübner, Torsten Hain, Trinad Chakraborty, Burkhard Linke, Alexander Goesmann, Sonja Voget, Rolf Daniel, Dietmar Schomburg, Rüdiger Hauck, Hafez M Hafez, Petra Tielen, Dieter Jahn, Margrete Solheim, Ewa Sadowy, Jesper Larsen, Lars B Jensen, Patricia Ruiz-Garbajosa, Dianelys Quiñones Pérez, Theresa Mikalsen, Jennifer Bender, Matthias Steglich, Ulrich Nübel, Wolfgang Witte, Guido Werner
Enterococcus faecalis is a multifaceted microorganism known to act as a beneficial intestinal commensal bacterium. It is also a dreaded nosocomial pathogen causing life-threatening infections in hospitalised patients. Isolates of a distinct MLST type ST40 represent the most frequent strain type of this species, distributed worldwide and originating from various sources (animal, ...... hiện toàn bộ
Genomic features and computational identification of human microRNAs under long-range developmental regulation
Springer Science and Business Media LLC - Tập 12 Số 1 - 2011
Ying Sheng, Christopher Previti
A bioinformatic survey of RNA-binding proteins in Plasmodium
Springer Science and Business Media LLC - Tập 16 - Trang 1-26 - 2015
BP Niranjan Reddy, Sony Shrestha, Kevin J. Hart, Xiaoying Liang, Karen Kemirembe, Liwang Cui, Scott E. Lindner
The malaria parasites in the genus Plasmodium have a very complicated life cycle involving an invertebrate vector and a vertebrate host. RNA-binding proteins (RBPs) are critical factors involved in every aspect of the development of these parasites. However, very few RBPs have been functionally characterized to date in the human parasite Plasmodium falciparum. Using different bioinformatic methods...... hiện toàn bộ
Recent CR1 non-LTR retrotransposon activity in coscoroba reveals an insertion site preference
Springer Science and Business Media LLC - Tập 9 - Trang 1-6 - 2008
Judy St John, Thomas W Quinn
Chicken repeat 1 (CR1) is a taxonomically widespread non-LTR retrotransposon. Insertion site bias, or lack thereof, has not been demonstrated for CR1. Recent CR1 retrotranspositions were used to examine flanking regions for GC content and nucleotide bias at the insertion site. Elucidation of the exact octomer repeat sequence (TTCTGTGA) allowed for the identification of younger insertion events. Th...... hiện toàn bộ
Generation and analysis of expressed sequence tags from six developing xylem libraries in Pinus radiata D. Don
Springer Science and Business Media LLC - - 2009
Xinguo Li, Harry X. Wu, Shannon Dillon, Simon G. Southerton
Abstract Background Wood is a major renewable natural resource for the timber, fibre and bioenergy industry. Pinus radiata D. Don is the most important commercial plantation tree species in Australia and several other countries; however, genomic resources for this speci...... hiện toàn bộ
Gene expression profile of rat left ventricles reveals persisting changes following chronic mild exercise protocol: implications for cardioprotection
Springer Science and Business Media LLC - Tập 10 - Trang 1-13 - 2009
Betti Giusti, Marina Marini, Luciana Rossi, Ilaria Lapini, Alberto Magi, Andrea Capalbo, Rosa Lapalombella, Simona di Tullio, Michele Samaja, Fabio Esposito, Vittoria Margonato, Maria Boddi, Rosanna Abbate, Arsenio Veicsteinas
Epidemiological studies showed that physical exercise, specifically moderate lifelong training, is protective against cardiovascular morbidity and mortality. Most experimental work has focused into the effects and molecular mechanisms underlying intense, rather than mild exercise, by exploring the acute effect of training. Our study aims at investigating the cardioprotective effect of mild chronic...... hiện toàn bộ
Interaction between Rag genes results in a unique synergistic transcriptional response that enhances soybean resistance to soybean aphids
Springer Science and Business Media LLC - - 2021
Martha I. Natukunda, Jessica D. Hohenstein, Chantal E. McCabe, Michelle A. Graham, Yunhui Qi, Asheesh K. Singh, Gustavo C. MacIntosh
Abstract Background Pyramiding different resistance genes into one plant genotype confers enhanced resistance at the phenotypic level, but the molecular mechanisms underlying this effect are not well-understood. In soybean, aphid resistance is conferred by Rag genes. We co...... hiện toàn bộ
Anti-masculinization induced by aromatase inhibitors in adult female zebrafish
Springer Science and Business Media LLC - Tập 21 - Trang 1-10 - 2020
Lu Chen, Li Wang, Qiwei Cheng, Yi-Xuan Tu, Zhuang Yang, Run-Ze Li, Zhi-Hui Luo, Zhen-Xia Chen
Early sex differentiation genes of zebrafish remain an unsolved mystery due to the difficulty to distinguish the sex of juvenile zebrafish. However, aromatase inhibitors (AIs) could direct juvenile zebrafish sex differentiation to male and even induce ovary-to-testis reversal in adult zebrafish. In order to determine the transcriptomic changes of sex differentiation in juvenile zebrafish and early...... hiện toàn bộ
A novel method to identify gene interaction patterns
Springer Science and Business Media LLC - Tập 22 - Trang 1-15 - 2021
Xinguo Lu, Fang Liu, Qiumai Miao, Ping Liu, Yan Gao, Keren He
Gene interaction patterns, including modules and motifs, can be used to identify cancer specific biomarkers and to reveal the mechanism of tumorigenesis. Most of the existing module network inferencing methods focus on gene independent functional patterns, while the studies of overlapping characteristics between modules are lacking. The objective of this study was to reveal the functional overlapp...... hiện toàn bộ
Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics
Springer Science and Business Media LLC - Tập 19 - Trang 1-16 - 2018
Kelly Street, Davide Risso, Russell B. Fletcher, Diya Das, John Ngai, Nir Yosef, Elizabeth Purdom, Sandrine Dudoit
Single-cell transcriptomics allows researchers to investigate complex communities of heterogeneous cells. It can be applied to stem cells and their descendants in order to chart the progression from multipotent progenitors to fully differentiated cells. While a variety of statistical and computational methods have been proposed for inferring cell lineages, the problem of accurately characterizing ...... hiện toàn bộ
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