Avibacterium paragallinarum: an emerging birds pathogen in Qinling wildlife conservation center, China
Honglin Xie, Hui Li, Chunyan Yu, Yongqiang Miao, Yaping Wu, Ruo Jia, Qiang Zhang, Genxing Pan, Qiang Ma, Kang-Sheng Jia, Xinglong Wang
AbstractThe bacterium Avibacterium paragallinarum, previously known as Haemophilus paragallinarum, is responsible for causing infectious coryza (IC) in chickens and other avian species. In this case report, an outbreak of Avibacterium paragallinarum occurred in the Qinling area of Chin...... hiện toàn bộ
CRISPR-Cas9 mediated phage therapy as an alternative to antibiotics Tập 3 Số 1
Fikre Birhanu Balcha, Sultan Abda Neja
AbstractInappropriate use of antibiotics is globally creating public health hazards associated with antibiotic resistance. Bacteria often acquire antibiotic resistance by altering their genes through mutation or acquisition of plasmid-encoding resistance genes. To treat drug-resistant strains of bacteria, the recently developed CRISPR-Cas9 system might be an altern...... hiện toàn bộ
Design of live-attenuated animal vaccines based on pseudorabies virus platform Tập 2 Số 1 - 2022
Zhen Liu, Zhengjie Kong, Meng Chen, Yue Shang
AbstractPseudorabies virus (PRV) is a double-stranded DNA virus with a genome approximating 150 kb in size. PRV contains many non-essential genes that can be replaced with genes encoding heterogenous antigens without affecting viral propagation. With the ability to induce cellular, humoral and mucosal immune responses in the host, PRV is considered to be an ideal a...... hiện toàn bộ
Isolation of a feline-derived feline panleukopenia virus with an A300P substitution in the VP2 protein and confirmation of its pathogenicity in dogs
Jiakang Li, Juan Peng, Yuan Zeng, Ying Wang, Luying Li, Yiran Cao, Longlong Cao, Qingxiu Chen, Zijun Ye, Shengbo Cao, Qiuyan Li
AbstractFeline panleukopenia virus (FPV) is a single-stranded DNA virus that can infect cats and cause feline panleukopenia, which is a highly contagious and fatal disease in felines. The sequence of FPV is highly variable, and mutations in the amino acids of its capsid protein play crucial roles in altering viral virulence, immunogenicity, host selection, and othe...... hiện toàn bộ
Identification of tick-borne pathogens using metagenomic analyses in H. longicornis feeding on humans in downtown Beijing - 2021
Jizhou Lv, Huiyu Wang, Xueqing Han, Lin Mei, Xin Yuan, Yufang Kong, Junhua Deng, Zhen F. Fu, Shaoqiang Wu, Xiaoyang Lin
AbstractOn August 14th, 2018, a Beijing resident living in Xicheng District found a female H. longicornis tick attached to the skin at the front of his upper shin. On examination, the patient was afebrile and appeared well. The species of the tick was identified through morphological characteristics and phylogenetic analysis based on cyto...... hiện toàn bộ
Chinese herbal extracts with antiviral activity: evaluation, mechanisms, and potential for preventing PRV, PEDV and PRRSV infections Tập 3 Số 1
Yuqiang Sun, Chang Li, Zhongzhu Liu, Wei Zeng, Muhammad Jamil Ahmad, Mengjia Zhang, Lina Liu, Shujun Zhang, Wentao Li, Qigai He
AbstractThe rapid expansion of large-scale pig farming has brought about a surge in viral diseases with high morbidity rates and diverse manifestations. This widespread occurrence of multiple viral diseases in pig farms has inflicted severe economic losses on the global swine industry. Consequently, there is an urgent need for eco-friendly and efficient antiviral d...... hiện toàn bộ
Molecular characterization and pathogenicity of Mycoplasma capricolum subsp. capricpolum from goats in Morocco - 2022
Noha Semmate, Zaid Zouagui, Zouhair Elkarhat, Zahra Bamouh, Siham Fellahi, Noursaid Tligui, Zineb Boumart, Ouafaa Fassi Fihri, Mehdi El Harrak
AbstractMycoplasma capricolum subsp. capricolum (Mcc) is an important etiological agent of contagious agalactia (CA). CA affects small ruminants and is characterized by inducing mastitis, arthritis, kerato-conjunctivitis and respiratory symptoms. The aim of this study was to isolate and characterize Mcc from Moroccan goats with contagious...... hiện toàn bộ
Selenium nanoparticles reduce oxidative stress-induced cardiomyocyte apoptosis in ascites syndrome in broiler chickens via the ATF6-DR5 signaling pathway Tập 3 Số 1
Xiaoqi Yang, Xin Liu, Jiaqi Liu, Penglong Wu, Yang Fu, San Loon Kyein, Jiabin Zhang, Mengdi Zhang, Yuxuan Peng, Diana Zhou
AbstractBroiler ascites syndrome (AS) is one of the main diseases threatening the health of broilers. It is well documented that myocardial hypertrophy and failure is one of the key mechanisms of broiler ascites syndrome. Therefore, prevention of cardiac hypertrophy and failure would be one goal to reduce broiler ascites syndrome incidence. Myocardial hypertrophy a...... hiện toàn bộ