Receptor autoimmunity: diagnostic and therapeutic implicationsSpringer Science and Business Media LLC - Tập 11 - Trang 1-7 - 2020
Renato Tozzoli
Receptor autoimmunity is one of the ways in which autoimmune diseases appear in
humans. Graves’ disease, myasthenia gravis, idiopathic membranous nephropathy,
and autoimmune acute encephalitis are the major autoimmune diseases belonging to
this particular group. Receptor autoimmune disease are dependent on the presence
of autoantibodies directed against cell-surface antigens, namely TSH receptor i... hiện toàn bộ
Recognition of the dense fine speckled (DFS) pattern remains challenging: results from an international internet-based surveySpringer Science and Business Media LLC - Tập 7 - Trang 1-7 - 2016
Chelsea Bentow, Marvin J. Fritzler, Eckart Mummert, Michael Mahler
The dense fine speckled (DFS) pattern as detected by indirect immunofluorescence
(IIF) on HEp-2 cells has been associated with several inflammatory diseases but
is most commonly observed in individuals that do not have an antinuclear
antibody (ANA)-associated rheumatic disease and even in apparently healthy
individuals. Consequently, the accurate identification and correct reporting of
this IIF pa... hiện toàn bộ
An unusual association of three autoimmune disorders: celiac disease, systemic lupus erythematosus and Hashimoto’s thyroiditisSpringer Science and Business Media LLC - Tập 7 - Trang 1-3 - 2016
Viera Boccuti, Antonio Perrone, Alessia D’Introno, Anna Campobasso, Moris Sangineto, Carlo Sabbà
Autoimmune disorders are known to be more frequent in women and often associated
each others, but it is rare to see multiple autoimmune diseases in a single
patient. Recently, the concept of multiple autoimmune syndrome has been
introduced to describe patients with at least three autoimmune diseases. We
describe a case of a young man with a clinical history of psychiatric symptoms
and celiac disea... hiện toàn bộ
The immunopathogenetic role of autoantibodies in canine autoimmune hepatitis: lessons to learn from human autoimmune hepatitisSpringer Science and Business Media LLC - Tập 3 - Trang 87-93 - 2012
Christos Liaskos, Athanasios Mavropoulos, Timoklia Orfanidou, Vassiliki Spyrou, Labrini V. Athanasiou, Charalambos Billinis
Autoimmune hepatitis (AIH) is not a disease entity restricted to man, but it can
be found in other animals including canines. An increasing number of studies
have focused on the immunopathogenesis of human autoimmune hepatitis (hAIH), but
little is known of what triggers canine autoimmune hepatitis (cAIH). Several
drugs, toxins, microbial and viral agents are able to induce autoantibodies and
inde... hiện toàn bộ
Transformation of fibroblast‐like synoviocytes in rheumatoid arthritis; from a friend to foeSpringer Science and Business Media LLC - Tập 12 - Trang 1-13 - 2021
Mohammad Javad Mousavi, Jafar Karami, Saeed Aslani, Mohammad Naghi Tahmasebi, Arash Sharafat Vaziri, Ahmadreza Jamshidi, Elham Farhadi, Mahdi Mahmoudi
Swelling and the progressive destruction of articular cartilage are major
characteristics of rheumatoid arthritis (RA), a systemic autoimmune disease that
directly affects the synovial joints and often causes severe disability in the
affected positions. Recent studies have shown that type B synoviocytes, which
are also called fibroblast-like synoviocytes (FLSs), as the most commonly and
chiefly re... hiện toàn bộ
Rhabdomyolysis secondary to systemic lupus erythematosusSpringer Science and Business Media LLC - Tập 9 - Trang 1-4 - 2018
Daniel Nguyen, Farah Alsaati, Jena Deitrick, Kamel Azhar, Evelyn Sbar
Systemic lupus erythematous (SLE) is a systemic auto-immune disorder with a
variety of presentations and wide spread organ involvement. We present a case
report of a patient with an SLE exacerbation as well as concurrent
rhabdomyolysis with massively elevated CPK (304,700 U/L). Though a rarely
reported effect of SLE, rhabdomyolysis can be severe and potentially lethal
secondary or concurrent to an... hiện toàn bộ
Association between autoimmune diseases and COVID-19 as assessed in both a test-negative case–control and population case–control designSpringer Science and Business Media LLC - Tập 11 - Trang 1-10 - 2020
Rossella Murtas, Anita Andreano, Federico Gervasi, Davide Guido, David Consolazio, Sara Tunesi, Laura Andreoni, Maria Teresa Greco, Maria Elena Gattoni, Monica Sandrini, Antonio Riussi, Antonio Giampiero Russo
COVID-19 epidemic has paralleled with the so called infodemic, where countless
pieces of information have been disseminated on putative risk factors for
COVID-19. Among those, emerged the notion that people suffering from autoimmune
diseases (AIDs) have a higher risk of SARS-CoV-2 infection. The cohort included
all COVID-19 cases residents in the Agency for Health Protection (AHP) of Milan
that, f... hiện toàn bộ
Sustained clinical remission under infliximab/rituximab combination therapy in a patient with granulomatosis with polyangiitisSpringer Science and Business Media LLC - Tập 12 - Trang 1-3 - 2021
Larissa Valor-Méndez, Arnd Kleyer, Jürgen Rech, Bernhard Manger, Georg Schett
Granulomatosis with polyangiitis (GPA) is a systemic autoimmune disease
characterized by small and medium vessel vasculitis. The use of biological
therapies such as rituximab and infliximab has improved the treatment of ocular
manifestations in GPA. We report a case of a 45-year-old Caucasian male
suffering with rhinitis, sinubronchitis and exophthalmos. These clinical
findings, subsequent biopsy ... hiện toàn bộ
Neutrophil/lymphocyte ratio and lymphocyte/monocyte ratio in ulcerative colitis as non-invasive biomarkers of disease activity and severitySpringer Science and Business Media LLC - Tập 10 - Trang 1-9 - 2019
Ashraf M. Okba, Mariam M. Amin, Ahmed S. Abdelmoaty, Hend E. Ebada, Amgad H. kamel, Ahmed S. Allam, Omar M. Sobhy
Apart from endoscopic interventions, readily attainable cost-effective
biomarkers for ulcerative colitis (UC) assessment are required. For this
purpose, we evaluated differential leucocytic ratio, mainly
neutrophil–lymphocyte ratio (NLR) and lymphocyte-monocyte ratio (LMR) as simple
available indicators of disease activity in patients with ulcerative colitis.
Study conducted on 80 UC patients who ... hiện toàn bộ
Current laboratory and clinical practices in reporting and interpreting anti-nuclear antibody indirect immunofluorescence (ANA IIF) patterns: results of an international surveySpringer Science and Business Media LLC - - 2020
Lieve Van Hoovels, Sylvia Broeders, Edward K. L. Chan, Luís Eduardo Coelho Andrade, Wilson de Melo Cruvinel, Jan Damoiseaux, M. Viander, Manfred Herold, Wim Coucke, Ingmar Heijnen, Dimitrios P. Bogdanos, Jaime Calvo‐Alén, Catharina Eriksson, Ana Kozmar, Liisa Kuhi, Carolien Bonroy, Bernard Lauwerys, Sofie Schouwers, Laurence Lutteri, Martine Vercammen, Miroslav Mayer, Dina Patel, William Egner, Kari Puolakka, Andrea Tesija-Kuna, Yehuda Shoenfeld, Maria José Rego de Sousa, Marcos Lόpez Hoyos, Antonella Radice, Xavier Bossuyt
Abstract Background The International Consensus on Antinuclear Antibody (ANA)
Patterns (ICAP) has recently proposed nomenclature in order to harmonize ANA
indirect immunofluorescence (IIF) pattern reporting. ICAP distinguishes
competent-level from expert-level patterns. A survey was organized to evaluate
reporting, familiarity, and considered clinical value of ANA IIF patterns.
Methods Two surveys... hiện toàn bộ