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Two-Beam Optical Traps: Refractive Index and Size Measurements of Microscale Objects
Springer Science and Business Media LLC - - 2005
Richard A. Flynn, Lei Lei, Mirianas Chachisvilis, Mihrimah Ozkan, Sadik C. Esener
A portable, integrated analyzer for microfluidic – based molecular analysis
Springer Science and Business Media LLC - Tập 13 - Trang 809-817 - 2011
Xianbo Qiu, Dafeng Chen, Changchun Liu, Michael G. Mauk, Terry Kientz, Haim H. Bau
A portable, fully automated analyzer that provides actuation and flow control to a disposable, self-contained, microfluidic cassette (“chip”) for point-of-care, molecular testing is described. The analyzer provides mechanical actuation to compress pouches that pump liquids in the cassette, to open and close diaphragm valves for flow control, and to induce vibrations that enhance stirring. The anal...... hiện toàn bộ
Low-stress Microfluidic Density-gradient Centrifugation for Blood Cell Sorting
Springer Science and Business Media LLC - Tập 20 - Trang 1-10 - 2018
Yuxi Sun, Palaniappan Sethu
Density gradient centrifugation exploits density differences between different blood cells to accomplish separation of peripheral blood mononuclear cells (PBMCs) from polymorphonuclear (PNM) cells, and erythrocytes or red blood cells (RBCs). While density gradient centrifugation offers a label-free alternative avoiding the use of harsh lysis buffers for blood cell isolation, it is a time-consuming...... hiện toàn bộ
Recent advances in optically induced di-electrophoresis and its biomedical applications
Springer Science and Business Media LLC - Tập 24 - Trang 1-25 - 2022
Shuxiang Cai, Zheng Ma, Zhixing Ge, Wenguang Yang
The development of the micro/nano science and technology has promoted the evolvement of human civilization tremendously. The advancement of the micro/nano science and technology highly depends on the progress of the micro/nano manipulation techniques, and the micro/nano-scaled manipulation level is the critical sign of the micro/nano science and technology. This review, aimed at the demand and the...... hiện toàn bộ
Cross-Talk Problem on a Fluorescence Multi-Channel Microfluidic Chip System
Springer Science and Business Media LLC - Tập 7 - Trang 205-211 - 2005
Rudi Irawan, Swee Chuan Tjin, Paul Yager, Dianwen Zhang
Development of a compact fluorescence-based detection system for use in a micro-analytical system, such as a point-of-care diagnostic system, often requires a multi-channel microfluidic chip system. Since the materials used for microfluidic chips usually are transparent in the visible region and have a refractive indices higher than that of air or the surrounding environment, the fluorescence emis...... hiện toàn bộ
A Micromachined Drop Dispenser for Biofluidics
Springer Science and Business Media LLC - - 2002
Steve P. Swierkowski
A micromachined drop dispenser for biofluidic applications has been fabricated and tested. It uses anisotropic etching of silicon and anodic bonding to pyrex wafers to form the flow channels, fluid wells, and nozzles. The ejected fluid comes from a fluid well that is externally compressed by a PZT bimorph that compresses a thin silicon membrane wall on the driven fluid well. This device design is ...... hiện toàn bộ
Analysis of Connective Tissue Progenitor Cell Behavior on Polydimethylsiloxane Smooth and Channel Micro-Textures
Springer Science and Business Media LLC - Tập 4 - Trang 267-275 - 2002
Alvaro Mata, Cynthia Boehm, Aaron J. Fleischman, George Muschler, Shuvo Roy
Growth of human connective tissue progenitor cells (CTPs) was characterized on smooth and microtextured polydimethylsiloxane (PDMS) surfaces. Human bone marrow derived cells were cultured for nine days under conditions promoting osteoblastic differentiation on Smooth PDMS and PDMS Channel microtextures (11 μm high, 45 μm wide channels, and separated by 5 μm wide ridges). Glass tissue culture dish ...... hiện toàn bộ
Dermatotoxicology of microneedles (MNs) in man
Springer Science and Business Media LLC - Tập 21 - Trang 1-8 - 2019
John Havens Cary, Becky S. Li, Howard I. Maibach
Developed within the last few decades, microneedles (MNs) have only recently seen wide-scale use among the general population, especially in the area of cosmetics. With the FDA only starting to regulate microneedling devices and the many new microneedling products that enter the modern global market, it is of utmost importance to establish the safety profile and reasonable expectations of the micr...... hiện toàn bộ
A novel, minimally invasive implant to assist in repeated intraocular drug delivery
Springer Science and Business Media LLC - Tập 24 - Trang 1-8 - 2022
Rohan Chawla, Jayanta Bhattacharyya, Laxmi Moksha, Anjali Phour, Thirumurthy Velpandian, Seema Kashyap, Dinesh Kalyanasundaram
The standard of care for posterior segment disorders such as wet age-related macular degeneration, diabetic macular oedema and retinal vascular occlusions is pharmacotherapy by intravitreal drug delivery. Since the therapeutic effect of these drugs lasts only around 4 to 8 weeks, repeated intravitreal injections are required. Pain is experienced by the patients during injection as the needle cours...... hiện toàn bộ
3D printing for preoperative planning and surgical training: a review
Springer Science and Business Media LLC - Tập 20 - Trang 1-24 - 2018
Anurup Ganguli, Gelson J. Pagan-Diaz, Lauren Grant, Caroline Cvetkovic, Mathew Bramlet, John Vozenilek, Thenkurussi Kesavadas, Rashid Bashir
Surgeons typically rely on their past training and experiences as well as visual aids from medical imaging techniques such as magnetic resonance imaging (MRI) or computed tomography (CT) for the planning of surgical processes. Often, due to the anatomical complexity of the surgery site, two dimensional or virtual images are not sufficient to successfully convey the structural details. For such sce...... hiện toàn bộ
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