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Using electrospun poly(ethylene-oxide) nanofibers for improved retention and efficacy of bacteriolytic antibiotics
Springer Science and Business Media LLC - Tập 15 - Trang 887-893 - 2013
John W. Gatti, Marie C. Smithgall, Shruti M. Paranjape, Ronda J. Rolfes, Makarand Paranjape
The aim of this study was to demonstrate targeted delivery of protein-based bactericidal antibiotics using electrospun polymer nanofibers. Previous studies have utilized electrospinning to create nanofibers for the localized delivery of therapeutic agents, including non-steroidal anti-inflammatory drugs (NSAIDs) and low molecular weight heparin. By employing established electrospinning techniques,...... hiện toàn bộ
Silicon micromachined ultrasonic scalpel for the dissection and coagulation of tissue
Springer Science and Business Media LLC - Tập 17 - Trang 1-12 - 2015
R. Lockhart, F. Friedrich, D. Briand, P. Margairaz, J.-P. Sandoz, J. Brossard, H. Keppner, W. Olson, T. Dietz, Y. Tardy, H. Meyer, P. Stadelmann, C. Robert, A. Boegli, P.-A. Farine, N. F. de Rooij, J. Burger
This work presents a planar, longitudinal mode ultrasonic scalpel microfabricated from monocrystalline silicon wafers. Silicon was selected as the material for the ultrasonic horn due to its high speed of sound and thermal conductivity as well as its low density compared to commonly used titanium based alloys. Combined with a relatively high Young’s modulus, a lighter, more efficient design for th...... hiện toàn bộ
A glass microchip device for conducting serological survey of West Nile viral antibodies
Springer Science and Business Media LLC - Tập 16 - Trang 737-743 - 2014
Javier Pena, Steven J. McAllister, Debashis Dutta
Serological surveys are vital to determining the prevalence of a disease and/or the immunity status against it in any population. However, the relatively large sample volume requirement (1–10 mL) in traditional serum-based assays demands that blood draw camps be set up by medical professionals to obtain samples for these studies which significantly increases the time and cost associated with them....... hiện toàn bộ
Miniaturized fiber-optic ultrasound probes for endoscopic tissue analysis by micro-opto-mechanical technology
Springer Science and Business Media LLC - Tập 16 - Trang 415-426 - 2014
E. Vannacci, L. Belsito, F. Mancarella, M. Ferri, G. P. Veronese, A. Roncaglia, E. Biagi
A new Micro-Opto-Mechanical System (MOMS) technology for the fabrication of optoacoustic probes on optical fiber is presented. The technology is based on the thermoelastic emission of ultrasonic waves from patterned carbon films for generation and on extrinsic polymer Fabry-Perot acousto-optical transducers for detection, both fabricated on miniaturized single-crystal silicon frames used to mount ...... hiện toàn bộ
Fabrication and characterization of hyaluronic acid microneedles to enhance delivery of magnesium ascorbyl phosphate into skin
Springer Science and Business Media LLC - - 2019
Yujin Kim, Sonalika Arup Bhattaccharjee, Moritz Beck-Broichsitter, Ajay K. Banga
Segmenting Fluid Effect on PCR Reactions in Microfluidic Platforms
Springer Science and Business Media LLC - Tập 7 - Trang 269-272 - 2005
E. J. Walsh, C. King, R. Grimes, A. Gonzalez
This paper evaluates the compatibility of segmenting fluids for two phase flow applications in biomedical microdevices. The evaluated fluids are chosen due to the variations in fluid properties and cost, while also reflecting their use in the recent literature. These segmenting fluids are examined to determine their compatibility with the Polymerase Chain Reaction (PCR), through controlled experim...... hiện toàn bộ
Magnetic-bead-based microfluidic system for ribonucleic acid extraction and reverse transcription processes
Springer Science and Business Media LLC - Tập 11 - Trang 339-350 - 2008
Chien-Ju Liu, Kang-Yi Lien, Ching-Yi Weng, Jyh-Wei Shin, Tsuey-Yu Chang, Gwo-Bin Lee
This paper presents a new integrated microfluidic chip that automatically performs ribonucleic acid (RNA) extraction and reverse transcription (RT) processes. The microfluidic system consists of a microfluidic control module and a magnetic bio-separator. The microfluidic control module can perform pumping and mixing of small amount of fluids and subsequent purification and concentration of RNA sam...... hiện toàn bộ
Powerful actuation of magnetized microtools by focused magnetic field for particle sorting in a chip
Springer Science and Business Media LLC - Tập 12 - Trang 745-752 - 2010
Yoko Yamanishi, Shinya Sakuma, Kazuhisa Onda, Fumihito Arai
This paper describes a novel powerful noncontact actuation of a magnetically driven microtool (MMT), achieved by magnetization of the MMT and focusing of the magnetic field in a microfluidic chip for particle sorting. The following are the highlights of this study: (1) an MMT was successfully fabricated from a mixture of neodymium powder and polydimethylsiloxane; the MMT was magnetized such that i...... hiện toàn bộ
Selective pattern of cancer cell accumulation and growth using UV modulating printing of hydrogels
Springer Science and Business Media LLC - - 2015
Wenguang Yang, Haibo Yu, Fanan Wei, Gongxin Li, Yuechao Wang, Lianqing Liu
Fabrication of polymer microstructures for MEMS: sacrificial layer micromolding and patterned substrate micromolding
Springer Science and Business Media LLC - Tập 9 - Trang 815-821 - 2007
Nicholas Ferrell, James Woodard, Derek Hansford
Two soft lithography based fabrication techniques are employed for fabricating mechanically independent, freely suspended polymer microstructure from poly(n-propyl methacrylate) (PPMA), poly(methyl methacrylate) (PMMA), and polystyrene. Both methods involve a micromolding process followed by thermal bonding to the substrate. The first method, sacrificial layer micromolding, uses a water soluble sa...... hiện toàn bộ
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