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Trajectories of objectively measured physical function among older breast cancer survivors in comparison with cancer-free controls
Springer Science and Business Media LLC - - 2022
Juhua Luo, Stephen J. Carter, Elizabeth M. Cespedes Feliciano, Michael Hendryx
Contralateral risk-reducing mastectomy in young women
Springer Science and Business Media LLC - Tập 123 - Trang 29-32 - 2010
Belén Merck
Survival and level of care among breast cancer patients with brain metastases treated with whole brain radiotherapy
Springer Science and Business Media LLC - Tập 166 - Trang 887-896 - 2017
Gabriella Frisk, Beatrice Tinge, Sara Ekberg, Sandra Eloranta, L. Magnus Bäcklund, Elisabet Lidbrink, Karin E. Smedby
The benefit of whole brain radiotherapy (WBRT) for late stage breast cancer patients with brain metastases has been questioned. In this study we evaluated survival and level of care (hospital or home) following WBRT in a population-based cohort by personal and tumor characteristics. We identified 241 consecutive patients with breast cancer and brain metastases receiving WBRT in Stockholm, Sweden, ...... hiện toàn bộ
Mammary field cancerization: molecular evidence and clinical importance
Springer Science and Business Media LLC - Tập 118 - Trang 229-239 - 2009
Christopher M. Heaphy, Jeffrey K. Griffith, Marco Bisoffi
The term “field cancerization” originally denoted the presence of histologically abnormal tissue/cells surrounding primary tumors of the head and neck. Similar concepts with different and continuously changing definitions have been used for other types of tumors including breast adenocarcinoma, where field cancerization presently denotes the occurrence of molecular alterations in histologically no...... hiện toàn bộ
Relationship between c-erbB-2 immunoreactivity and thymidine labelling index in breast carcinomain situ
Springer Science and Business Media LLC - Tập 18 - Trang 11-17 - 1991
Diana M. Barnes, J. S. Meyer, J. G. Gonzalez, W. J. Gullick, Rosemary R. Millis
The relationship between the presence of the c-erbB-2 protein, demonstrated immunohistochemically with antibody 21N, and thymidine labelling index (TLI) has been studied in thein situ component of 70 cases of carcinoma of the breast. A significant association was found between high TLI and positive staining. Twenty of the 70 cases stained (29%) and of those that were stained 75% had a high TLI; 43...... hiện toàn bộ
Clinical recognition and management of depression in node negative breast cancer patients treated with tamoxifen
Springer Science and Business Media LLC - Tập 27 - Trang 277-281 - 1993
Cynthia K. Cathcart, Stephen E. Jones, C. Sue Pumroy, George N. Peters, Sally M. Knox, J. Harold Cheek
Depression is not an uncommon complaint of women with breast cancer and is usually assumed to be related to the cancer diagnosis itself or its treatment. As part of a prospective clinical trial of adjuvant therapy of node negative breast cancer, 301 patients treated and assessed by one oncologist (SEJ) were serially questioned for symptoms of depression in the first 6–12 months after completing in...... hiện toàn bộ
Histologic findings in normal breast tissues: comparison to reduction mammaplasty and benign breast disease tissues
Springer Science and Business Media LLC - Tập 133 - Trang 169-177 - 2011
Amy C. Degnim, Daniel W. Visscher, Tanya L. Hoskin, Marlene H. Frost, Robert A. Vierkant, Celine M. Vachon, V. Shane Pankratz, Derek C. Radisky, Lynn C. Hartmann
Investigations of breast carcinogenesis often rely upon comparisons between cancer tissue and nonmalignant breast tissue. It is unclear how well common reference sources of nonmalignant breast tissues reflect normal breast tissue. Breast tissue samples were evaluated from three sources: (1) normal donor tissues in the Susan G. Komen for the Cure® Tissue Bank at Indiana University Simon Cancer Cent...... hiện toàn bộ
Cyclin D1 expression is associated with poor prognostic features in estrogen receptor positive breast cancer
Springer Science and Business Media LLC - Tập 113 - Trang 75-82 - 2008
Kirsimari Aaltonen, Rose-Marie Amini, Göran Landberg, Hannaleena Eerola, Kristiina Aittomäki, Päivi Heikkilä, Heli Nevanlinna, Carl Blomqvist
Cyclins D1 and E play an important role in breast carcinogenesis. High cyclin E expression is common in hormone receptor negative and high grade aggressive breast cancer, whereas cyclin D1 in hormone receptor positive and low grade breast cancer. Experimental data has suggested that cyclin D1 and E mediate cell proliferation by different mechanisms in estrogen receptor (ER) positive and negative b...... hiện toàn bộ
Inhibition of Breast Cancer Regrowth and Pulmonary Metastasis in Nude Mice by Anti-gastric Ulcer Agent, Irsogladine
Springer Science and Business Media LLC - Tập 83 - Trang 195-199
Shinichi Nozaki, Mitsuaki Maeda, George W. Sledge, Hiroyuki Tsuda
Irsogladine is a commonly used anti-gastric ulcer agent in Japan, and recent in vivo studies have shown it to have anti-angiogenic properties. The exact role of irsogladine as an inhibitor of angiogenesis remains uncertain. In this study, we show that irsogladine inhibited breast cancer regrowth and pulmonary metastasis but had no anti-angiogenic function against HUVEC cells. Irsogladine failed to...... hiện toàn bộ
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