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Correction to: Quantitative proteomic analysis reveals differential modulation of crucial stage specific proteins during promastigote to amastigote differentiation in Leishmania donovani
Springer Science and Business Media LLC - Tập 13 - Trang 125-125 - 2022
Chinmayee Bar Routaray, Vaibhavee Choudhari, Divya Prakash, Rajendra Patil, Surabhi Jagtap, Shakuntala Bai, Mahesh J. Kulkarni, Suresh V. Kuchipudi, Kalpana Pai
Differential proteomics reveals overexpression of ferroptosis-related proteins in cervical cancer tissue
Springer Science and Business Media LLC - Tập 14 - Trang 163-174 - 2023
Kumari Binita Chandra, Anil Kumar Tomar, Ayushi Thapliyal, Jai Bhagwan Sharma, Neerja Bhatla, Savita Yadav
Cervical cancer, the fourth most common female cancer, is one of the major global health challenges. Because of the high prevalence rate, women are frequently screened for cervical cancer using Pap smears; however, the low sensitivity of Pap smear results in a late-stage diagnosis of cervical cancer. This study was designed to identify candidate biomarkers of cervical cancer, which can be explored... hiện toàn bộ
Heterologous expression, purification, and proteomic characterization of a 37 kDa pupal gut serine protease from Bombyx mori in Escherichia coli
Springer Science and Business Media LLC -
Mani Kannan, Nagarajan Kayalvizhi, Vimalanathan Arunprasanna, Neelamegam Rameshkumar, T. Suganya, Muthukalingan Krishnan
Unravelling the natural dual-target inhibiting potential of cucurbit bioactive compounds for the management of cucumber mosaic virus (CMV) through computational approaches
Springer Science and Business Media LLC - Tập 12 - Trang 307-324 - 2021
Roshni Mohan Kumar, Ramachandra Anantapur, Anitha Peter
Cucumber mosaic virus (CMV), one of the top ten most devastating plant pathogenic viruses infects nearly 1300 crop species causing huge economic losses. It is transmitted by more than 80 aphid species (Insecta: Hemiptera: Aphidoidea) including Myzus persicae and Aphis gossypii in a non-persistent, stylet-borne manner. The coat protein (CP) of the virus is identified as the primary determinant for ... hiện toàn bộ
Rapid and deep plasma proteomics workflows for robust identification and quantification of biomarkers of sickle cell anaemia
Springer Science and Business Media LLC - Tập 13 - Trang 205-218 - 2022
Sravani Polepalli, Richa Singh, Shoma Naskar, Pasupuleti SKDB Punyasri, Kongari Ranjith Kumar, Kameshwari Yele, Viswanatha Krishnakumari, Raman Bakthisaran, Dipty Jain, Giriraj Ratan Chandak, Swasti Raychaudhuri
Plasma serves as a rich source of protein biomarkers but in-depth proteomic analysis is challenging due to vast dynamic range of protein abundance. Pre-fractionation of plasma proteins is commonly practiced to enhance the proteome coverage but the protocols are time-expensive, suffer from flowchart complexity, and often less reproducible. Here, we explore multiple strategies of shotgun proteomics ... hiện toàn bộ
Proteogenomics 101: a primer on database search strategies
Springer Science and Business Media LLC - Tập 14 Số 4 - Trang 287-301
Anurag Raj, Suruchi Aggarwal, Dhirendra Kumar, Amit Kumar Yadav, Debasis Dash
Identification of potential inhibitors of shikimate kinase from Mycobacterium tuberculosis using in silico approach
Springer Science and Business Media LLC - - 2024
Mustafa Alhaji Isa, Mohammed Mustapha Mohammed, Muhammad Musa Ibrahim, Falmata Audu Gubio, Fatimah Buba, Somia Shehzadi
Shikimate kinase is an enzyme that plays a crucial role in the biosynthesis of aromatic amino acids. It is integral to the fifth step of the shikimate pathway, transferring a phosphoryl group from ATP to shikimate, yielding ADP and shikimate-3-phosphate within Mycobacterium tuberculosis (Mtb). This enzyme is an attractive target for drug discovery, especially against pathogens like Mtb that rely o... hiện toàn bộ
Will “CLINICAL PROTEOMICS” lead to the discovery of new biomarkers for dilated cardiomyopathy (DCM)?
Springer Science and Business Media LLC - Tập 14 - Trang 79-80 - 2023
Shubham Saha, Vivek Sarohi, Trayambak Basak
Proteomic and metabolomic analysis of Nothapodytes nimmoniana (J. Graham) extracts’ treatment on HeLa cells
Springer Science and Business Media LLC - Tập 11 - Trang 27-62 - 2020
Shivani Gayakwad, Amey Shirolkar, Shrikant Warkad, Shraddha Bharsakale, Sudesh Gaidhani, Sharad Pawar
Nothapodytes nimmoniana is a natural source of camptothecin, a known anticancer drug. Stem and leaf extracts of Nothapodytes nimmoniana were studied to assess its in vitro action on cancer progression events in a cervical cancer cell line, the HeLa. As a well-studied ideal model system, the HeLa has been chosen and the effects of extracts on cancer progression events have been traced out. HeLa cel... hiện toàn bộ
A review on-analytical tools in proteomics
Springer Science and Business Media LLC - Tập 14 - Trang 201-221 - 2023
Archana K. Thikekar, Vishal S. Rathod, Varsharani P. Panchal, Samruddhi A. Raut, Rohan S. Raut, Kishor S. Jain
Proteomics is an analytical technique employed for the identification and quantitative analysis of total protein content in a cell, tissue or organism using various methods and tools. Proteomics succeeds in genomics (study of set of DNA) and transcriptomics (study of set of RNA) of biological systems. A proteome is an array of proteins generated by a particular organism, system, or biological cond... hiện toàn bộ
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