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Subtotal perirhinal cortex lesions increase exploratory behavior in the rat without producing deficits in the Morris water maze
Springer Science and Business Media LLC - Tập 22 - Trang 195-202 - 2013
Kjesten A. Wiig, David K. Bilkey
Rats with bilateral, subtotal lesions of the superficial layers of perirhinal cortex were tested in a reaction-to-novelty procedure and in the Morris water maze. Lesioned rats spent significantly more time than did control animals in exploring objects in the reaction-to-novelty test apparatus. In addition, lesioned rats exhibited increased rearing, both in the exploration procedure and in an open ... hiện toàn bộ
Behavior from the ground up: Rat behavior from the ventral perspective
Springer Science and Business Media LLC - - 1992
John P. J. Pinel, Craig Hilton Jones, Ian Q. Whishaw
Spatial learning in preweanling rats trained in a Morris water maze
Springer Science and Business Media LLC - Tập 23 - Trang 144-152 - 2013
Philipp J. Kraemer, Christopher K. Randall
In three experiments, spatial learning in preweanling rats was examined, using the Morris water maze (MWM). Contrary to previous findings, Experiment 1 revealed that rat pups younger than 20 days of age showed good spatial learning. Experiment 2 revealed that spatial learning in preweanlings was influenced by the nature of the training procedure; a spaced distribution of trials resulted in good sp... hiện toàn bộ
5,7-DHT—induced lesions of the nucleus basalis or frontal cortex do not block passive avoidance retention impairments produced by p-chloroamphetamine in rats
Springer Science and Business Media LLC - Tập 23 Số 2 - Trang 139-143 - 1995
Anthony C. Santucci, P. J. Knott, Vahram Haroutunian
Dopamine and hippocampal input to the nucleus accumbens play an essential role in the search for food in an unpredictable environment
Springer Science and Business Media LLC - - 1999
Stan B. Floresco, Anthony G. Phillips
Acute and chronic effects of clomipramine on isolation-induced aggression in male mice
Springer Science and Business Media LLC - Tập 22 - Trang 226-231 - 2013
J. J. Borrás-Valls, A. Salvador, V. M. Simón
The behavioral effects of clomipramine were studied on an ethopharmacological model of aggression. A range of low doses (similar to those used in clinical practice: 1.5, 3, and 6 mg/kg) and a higher dose (24 mg/kg—more usual in animal experimentation) were administered to isolated male mice that confronted anosmic opponents in a neutral arena. Encounters were staged 30 min after acute treatment an... hiện toàn bộ
Taste cues control ethanol-induced conditioned taste avoidance but not conditioned tolerance
Springer Science and Business Media LLC - Tập 19 - Trang 64-69 - 2013
Christopher L. Cunningham, Cheryl L. Hallett
This experiment tested the ability of taste cues to serve as the conditioned stimulus (CS) for conditioned tolerance to ethanol hypothermia. Rats were exposed to a differential Pavlovian conditioning procedure in which the manual oral infusion of one flavor solution was consistently followed by injection of ethanol (2.25 g/kg), whereas exposure to another flavor was followed by injection of saline... hiện toàn bộ
Long-term potentiation at the lateral perforant path-nucleus accumbens synapse in the rat in vivo
Springer Science and Business Media LLC - Tập 26 - Trang 169-175 - 2013
Alfredo Quiñones-Hinojosa, Brian E. Derrick, Edwin J. Barea-Rodriguez, Patricia H. Janak, Joe L. Martinez
The nucleus accumbens (NAcb), a basal forebrain structure implicated in drug-mediated reward, receives afferents from a variety of limbic and cortical structures, including the prefrontal cortex, the amygdala, the entorhinal cortex, and the subicular complex. In the present study, monosynaptic projections from the lateral entorhinal cortex (lateral perforant path) to the NAcb are shown to display ... hiện toàn bộ
Sex differences in radial maze performance: Influence of rearing environment and room cues
Springer Science and Business Media LLC - Tập 24 - Trang 33-37 - 2013
Penny Seymoure, Hui Dou, Janice M. Juraska
There have been conflicting reports on whether or not male rats outperform females in the radial arm maze. Three factors—rearing environment, room cues, and whether all of the maze arms are baited with food—may differentially influence the performance of male and female rats. In the present experiment, littermate male and female hooded rats were reared either in same-sex groups in a complex enviro... hiện toàn bộ
Evaluating models of the topographical organization of working memory function in frontal cortex with event-related fMRI
Springer Science and Business Media LLC - Tập 28 - Trang 132-145 - 2013
Bradley R. Postle, Mark D’esposito
Many influential claims about the organization of working memory function in prefrontal cortex (PFC) have been developed and/or tested with functional neuroimaging methods featuring the blocking of behavioral trials and the averaging across blocks of neuroimaging signal. Interpretation of the results of these first-generation neuroimaging studies is subject to several inferential constraints that ... hiện toàn bộ
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