DNA methylation of insulin-like growth factor 2 and H19 cluster in cord blood and prenatal air pollution exposure to fine particulate matterSpringer Science and Business Media LLC - Tập 19 - Trang 1-12 - 2020
Congrong Wang, Michelle Plusquin, Akram Ghantous, Zdenko Herceg, Rossella Alfano, Bianca Cox, Tim S. Nawrot
The IGF2 (insulin-like growth factor 2) and H19 gene cluster plays an important
role during pregnancy as it promotes both foetal and placental growth. We
investigated the association between cord blood DNA methylation status of the
IGF2/H19 gene cluster and maternal fine particulate matter exposure during fetal
life. To the best of our knowledge, this is the first study investigating the
associati... hiện toàn bộ
Does early life exposure to exogenous sources of reactive oxygen species (ROS) increase the risk of respiratory and allergic diseases in children? A longitudinal cohort studySpringer Science and Business Media LLC - Tập 21 - Trang 1-6 - 2022
Teresa To, Emilie Terebessy, Jingqin Zhu, Kimball Zhang, Pascale SJ Lakey, Manabu Shiraiwa, Marianne Hatzopoulou, Laura Minet, Scott Weichenthal, Sharon Dell, Dave Stieb
Excess reactive oxygen species (ROS) can cause oxidative stress damaging cells
and tissues, leading to adverse health effects in the respiratory tract. Yet,
few human epidemiological studies have quantified the adverse effect of early
life exposure to ROS on child health. Thus, this study aimed to examine the
association of levels of ROS exposure at birth and the subsequent risk of
developing comm... hiện toàn bộ
Non-disclosure of developmental neurotoxicity studies obstructs the safety assessment of pesticides in the European UnionSpringer Science and Business Media LLC - Tập 22 - Trang 1-21 - 2023
Axel Mie, Christina Rudén
In the European Union (EU), the safety assessment of plant protection products
relies to a large extent on toxicity studies commissioned by the companies
producing them. By law, all performed studies must be included in the dossier
submitted to authorities when applying for approval or renewal of the active
substance. For one type of toxicity, i.e. developmental neurotoxicity (DNT), we
evaluated i... hiện toàn bộ
Spatiotemporal analysis of particulate air pollution and ischemic heart disease mortality in Beijing, ChinaSpringer Science and Business Media LLC - Tập 13 - Trang 1-12 - 2014
Meimei Xu, Yuming Guo, Yajuan Zhang, Dane Westerdahl, Yunzheng Mo, Fengchao Liang, Xiaochuan Pan
Few studies have used spatially resolved ambient particulate matter with an
aerodynamic diameter of <10 μm (PM10) to examine the impact of PM10 on ischemic
heart disease (IHD) mortality in China. The aim of our study is to evaluate the
short-term effects of PM10 concentrations on IHD mortality by means of
spatiotemporal analysis approach. We collected daily data on air pollution,
weather condition... hiện toàn bộ