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Analysis of the Applicability of Molecular Markers Linked to the PVY Extreme Resistance Gene Rysto, and the Identification of New Markers
Springer Science and Business Media LLC - Tập 59 - Trang 195-203 - 2008
In this study molecular markers linked to the Rysto gene, which originates from the wild potato species Solanum stoloniferum and confers extreme resistance against PVY, were identified and the applicability of recently published Rysto markers was analyzed. Three RAPD markers covering a total distance of 8.60 cM were detected in this experiment. The closest of these markers was located 0.53 cM from......
Effect of Silver Nanoparticles on Phenolic Compounds Production and Biological Activities in Hairy Root Cultures of Cucumis Anguria
Springer Science and Business Media LLC - Tập 69 - Trang 97-109 - 2018
The present study describes the elicitor effect of silver ion (Ag+) and biologically synthesized silver nanoparticles (AgNPs) to enhance the biomass accumulation and phenolic compound production as well as biological activities (antioxidant, antimicrobial and anticancer) in genetically transformed root (hairy root) cultures of Cucumis anguria. The biomass of hairy root cultures was signifcantly in......
Morphological Analysis of the Connective Tissue Reaction in Linear Hypertrophic Scars Treated with Intralesional Steroid or Silicone-Gel Sheeting. A Light and Electron Microscopic Study
Springer Science and Business Media LLC - Tập 59 - Trang 129-145 - 2008
The linear hypertrophic scar has become the most common type of pathologic scarring. Silicone-gel sheeting is the first line therapy while intralesional steroid is the second. A. light and electron microscopic analysis was carried out to reveal differences in tissue reaction following the two different treatments. Two groups of 12 patients each were treated for 4 months. For the first group, dilut......
Activities and Functions of Peripheral Neurons in the Enteric Nervous System of Aplysia and Lymnaea
Springer Science and Business Media LLC - Tập 59 - Trang 65-71 - 2008
In order to explore the functions of the peripheral neurons in the enteric nervous system (ENS) of the gastropods, Aplysia and Lymnaea, we investigated the correlation between peripheral neuronal activities and movements of the digestive tract. In Aplysia, movements of the gizzard were distinguished into two types of contraction: a large constriction of the whole gizzard following bursting activit......
Peptides and antitumor activity
Springer Science and Business Media LLC - Tập 51 - Trang 1-29 - 2000
We developed a group of synthetic analogs of GnRH and Somatostatin to inhibit the tumor growth of different kind. The GnRH analogs decreasing the gonadotrop and steroid hormone levels act on the hormone dependent tumors and influence their growth. One of the most effective antitumor analog was patented under the name FOLLIGEN which inhibited the breast cancer caused by DMBA in rats without any sid......
Imidazoleacetic Acid-Ribotide in the Rodent Striatum: A Putative Neurochemical Link Between Motor and Autonomic Deficits in Parkinson’s Disease
Springer Science and Business Media LLC - Tập 63 - Trang 5-18 - 2012
We have previously demonstrated that imidazole-4-acetic acid-ribotide (IAA-RP) is present in the mammalian brain and is an endogenous ligand at imidazoline binding sites. In the present study, we used a polyclonal antiserum to visualize IAA-RP-containing neurons in the rat caudoputamen. We observe IAA-RP-immunostained neurons scattered throughout the dorsal and ventral striatum. Most of these cell......
Stereological Analysis of Thyroid Mast Cells in Rats After Exposure to Extremely Low Frequency Electromagnetic Field and the Following “off” Field Period
Springer Science and Business Media LLC - Tập 56 - Trang 43-51 - 2005
Influence of extremely low frequency electromagnetic field (ELF-EMF) on thyroid gland mast cells was investigated on male Mill Hill rats. Animals were exposed to EMF (50 Hz, 50 μT to 500 μT, 10 V/m) from 24 hours after birth, 7 hours/day, 5 days/week for three months when a part of animals (group I) was sacrificed, while the rest of them were subjected to recovery evaluation and sacrificed after o......
Potencies and Selectivities of Inhibitors of Acetylcholinesterase and Its Molecular Forms in Normal and Alzheimer’s Disease Brain
Springer Science and Business Media LLC - Tập 54 - Trang 183-189 - 2003
Eight inhibitors of acetylcholinesterase (AChE), tacrine, bis-tacrine, donepezil, rivastigmine, galantamine, heptyl-physostigmine, TAK-147 and metrifonate, were compared with regard to their effects on AChE and butyrylcholinesterase (BuChE) in normal human brain cortex. Additionally, the IC50 values of different molecular forms of AChE (monomeric, G1, and tetrameric, G4) were determined in the cer......
Presymptomatic diagnosis of familial colon polyposis
Springer Science and Business Media LLC - Tập 48 - Trang 377-383 - 1997
The gene responsible for familial adenomatous polyposis (FAP) has recently been mapped, identified and this makes the presymptomatic molecular diagnosis of the disease possible. It can be performed by direct mutation analysis or indirect haplotype analysis. In families where several affected individuals are available the indirect haplotype analysis is the easiest way for performing presymptomatic ......
Effect of Testosterone Loading on the Kinetic of Faecal Testosterone Excretion in Mallards
Springer Science and Business Media LLC - Tập 57 - Trang 13-21 - 2006
Intestinal passage time of coloured fodder and testosterone turnover were examined by faecal steroid analysis in mallards in the reproductive and postrefractory period. In the latter, the discharge of coloured fodder began 36 minutes after ingestion in males, and 56 minutes in females. During reproduction the discharge began 93 minutes and 112 minutes after ingestion in males and females, respecti......
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