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Recurrence of medulloblastoma 19 years after the initial diagnosis
Springer Science and Business Media LLC - - 1999
Kenichi Amagasaki, H. Yamazaki, Hidehito Koizumi, Kazuhiro Hashizume, Nobuo Sasaguchi
Paediatric supratentorial tumours do not cause microstructural alterations in contralateral white matter: a preliminary study
Springer Science and Business Media LLC - - Trang 1-6 - 2023
Barış Genç, Semra Delibalta, Kerim Aslan, Meltem Necibe Ceyhan Bilgici
Intracranial tumours in children can exhibit different characteristics compared to those in adults. Understanding the microstructural changes in the contralateral normal-appearing white matter (NAWM) in children with primary intracranial masses is essential for optimizing treatment strategies. This study aimed to investigate the apparent diffusion coefficient (ADC) changes in contralateral NAWM using fully automated methods and deep learning algorithms. We included 22 paediatric patients with primary supratentorial intracranial masses (23% high-grade) in the study. ADC values of the contralateral NAWM in the patient group were compared to those of a control group. Deep learning algorithms were utilized to analyse diffusion changes in NAWM. The mean ADC values of contralateral NAWM in the patient group were 0.80 ± 0.03 × 10−3 mm2/s, while the control group had a mean ADC value of 0.81 ± 0.03 × 10−3 mm2/s. There was no statistically significant difference between the groups (p = 0.39). Our findings indicate that there are no significant diffusion changes in the contralateral white matter of children with supratentorial intracranial masses. Primary supratentorial intracranial masses in children do not cause microstructural changes in contralateral normal-appearing white matter. This could be attributed to the less infiltrative nature and different biochemical profile of these tumour groups in the paediatric population. Further studies using advanced imaging techniques could provide additional insights into the distinct characteristics of paediatric intracranial tumours and improve patient management.
The role of age on helmet therapy in deformational plagiocephaly and asymmetric brachycephaly
Springer Science and Business Media LLC - Tập 36 Số 4 - Trang 803-810 - 2020
Serdar Çevik, Semra Işık, Alper Özkılıç
Intraoperative neurophysiology in pediatric neurosurgery: a historical perspective
Springer Science and Business Media LLC - Tập 39 - Trang 2929-2941 - 2023
Francesco Sala
Intraoperative neurophysiology (ION) has been established over the past three decades as a valuable discipline to improve the safety of neurosurgical procedures with the main goal of reducing neurological morbidity. Neurosurgeons have substantially contributed to the development of this field not only by implementing the use and refinement of ION in the operating room but also by introducing novel techniques for both mapping and monitoring of neural pathways. This review provides a personal perspective on the evolution of ION in a variety of pediatric neurosurgical procedures: from brain tumor to brainstem surgery, from spinal cord tumor to tethered cord surgery. The contribution of pediatric neurosurgeons is highlighted showing how our discipline has played a crucial role in promoting ION at the turn of the century. Finally, a view on novel ION techniques and their potential implications for pediatric neurosurgery will provide insights into the future of ION, further supporting the view of a functional, rather than merely anatomical, approach to pediatric neurosurgery.
H. Lanfermann, P. Raab, H-J Kretschmann, and W. Weinrich (Editors): Cranial neuroimaging and clinical neuroanatomy (fourth edition)
Springer Science and Business Media LLC - Tập 36 - Trang 1575-1575 - 2020
Mario Giordano
Endoscopic third ventriculostomy in the treatment of hydrocephalus in posterior fossa tumors in children
Springer Science and Business Media LLC - - 2004
Claudio Ruggiero, Giuseppe Cinalli, Pietro Spennato, Ferdinando Aliberti, Emilio Cianciulli, Vincenzo Trischitta, Giuseppe Maggi
The purpose of the present study is to assess the effectiveness of endoscopic third ventriculostomy (ETV) in children with hydrocephalus related to posterior fossa tumors. Between September 1999 and December 2002, 63 children with posterior fossa tumors were treated at Santobono Hospital in Naples, Italy. Twenty-six patients had severe hydrocephalus. In order to relieve intracranial hypertension before tumor removal, 20 were treated with ETV, and 6 with ventriculo-peritoneal (VP) shunts. Twenty patients with mild hydrocephalus were treated with diuretics, corticosteroid agents, and early posterior fossa surgery, and 17 patients who did not have hydrocephalus were treated by elective posterior fossa surgery. Another 4 ETV were performed in the management of postoperative hydrocephalus. Preoperative ETV procedures were technically successful. One was complicated by intraventricular bleeding. The successful 19 preoperative ETV resolved intracranial hypertension before posterior fossa surgery in all cases. Three of these 19 patients developed postoperative hydrocephalus and were treated by VP shunt insertion after posterior fossa surgery. Out of the 4 ETV performed after posterior fossa surgery, only 2 were successful, both when the shunt malfunctioned. Endoscopic third ventriculostomy should be considered as an alternative procedure to ventriculo-peritoneal shunting and external ventricular draining for the emergency control of severe hydrocephalus caused by posterior fossa tumors, since it can quickly eliminate symptoms, and hence, can delay surgery scheduling if required. Even though ETV does not prevent postoperative hydrocephalus in all cases, it does protect against acute postoperative hydrocephalus due to cerebellar swelling. In addition, it eliminates the risks of cerebrospinal fluid (CSF) infection related to external drainage and minimizes the risk of overdrainage because it provides more physiological CSF drainage than the other procedures. Since postoperative hydrocephalus is very often physically obstructive, ETV should always be considered a possible treatment procedure.
Progression of terminal syrinx in occult spina bifida
Springer Science and Business Media LLC - Tập 19 Số 5-6 - Trang 268-268 - 2003
Burak Sade, Liana Beni‐Adani, Liat Ben-Sira, Shlomi Constantini
Correlation of EEG, neuroimaging and histopathology in an epilepsy patient with diffuse cortical dysplasia
Springer Science and Business Media LLC - Tập 16 - Trang 75-79 - 2000
K. Hashizume, K. Kiriyama, M. Kunimoto, T. Maeda, T. Tanaka, A. Miyamoto, N. Miyokawa, M. Fukuhara
The correlation between scalp EEG, intraoperative electrocorticogram, neuroimaging and histopathology was examined in an epileptic child with diffuse cortical dysplasia. The 6-year-old girl with moderate mental retardation had suffered from intractable complex partial and generalized epilepsies since the age of 2 years. MR images demonstrated unilateral large macrogyria/polymicrogyria and schizencephaly in the right occipital lobe. The epileptic focus was detected on the macrogyria by EEG and single photon emission tomography. However, the intraoperative electrocorticogram showed frequent spikes from the polymicrogyria and no paroxysmal activity in the macrogyria. The polymicrogyria and the macrogyric lesion were resected, using an image-guided system. The histological findings revealed that the macrogyria was covered with and separated by glial bundles. It has been reported that epileptogenicity is produced from abnormal neurons and their arrangement in cortical dysplasia; in this case, however, the major dysplastic lesion had no epileptogenicity; rather the focus might be in the polymicrogyria around the lesion.
Proposal of a new method to induce ventricular system dilation to simulate the features of hydrocephalus and provide an anatomical model for neuroendoscopy training
Springer Science and Business Media LLC - Tập 30 - Trang 1209-1215 - 2014
Christian Diniz Ferreira, Hamilton Matushita, Bruno Roberto Duarte Silva, Arlindo Ugulino Netto, Luiz Gustavo Correia, Maurus Marques de Almeida Holanda, Rayan Haquim Pinheiro Santos
Create an anatomical model which simulates the real condition of a hydrocephalus and which can be used as a tool in the training of neurosurgeons in neuroendoscopy techniques and anatomical structure study. Case–control type study, with an experimental group consisting of ten brains, in which the injection of distilled water was performed; and the control group consisting of three brains with saline solution. Inclusion criteria were brains with no history of contagious diseases or traumatic injury. t student test showed that the relation between frontal horn and internal frontal diameter (FH/ID), with an average of 13 % before the experiment, had a significant difference (t = −3.47, df = 9, p < 0.01) from the relation after the subsequent experiment with an average of 20 %. The Evan’s index also showed a significant difference (t = −3.57, df = 9, p < 0.01) with an initial and final average of 12 % and 19 %, respectively. Friedman test showed significant difference of the size of the temporal horn before and after the experiment (f = 8.1, df = 1, p < 0.01), indicating that there was significant increase of the temporal horn. The adequate use of the anomalous chemical–physical characteristics of the water molecule may provide a good mechanism to expand the ventricular cavity, in order to create an experimental model of hydrocephalus. The endoscope may be introduced by the usual ways, allowing anatomical observation and simulation of the same tactile sensitivity that one would find during the actual procedure.
Correction: Ventriculosubgaleal shunts in the management of neonatal post-haemorrhagic hydrocephalus: technical note
Springer Science and Business Media LLC - Tập 39 - Trang 3273-3273 - 2023
Cristina Bleil, Francesca Vitulli, Asfand Baig Mirza, Timothy Martyn Boardman, Qusai Al Banna, Wisam Al-Faiadh, Bassel Zebian
Tổng số: 6,272   
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