High-Throughput Doppler Toolbox for Preclinical Drug DevelopmentSLAS Technology - Tập 15 - Trang 287-296 - 2010
Karim Azer, Michael C. Desiderio, Christopher Tong, Michelle Bunzel, Barry R. Campbell, Diane Shevell, Matthew Walker
Quantification of hemodynamics may be invaluable in a drug development setting.
However, one of the challenges in the application of imaging technologies for
compound screening purposes is the large volume of data in a short amount of
time. This article focuses on methods developed for large-scale hemodynamic
quantification, as measured from high-frequency Doppler ultrasound in rodents.
An integra... hiện toàn bộ
Modular Automation Platforms: A Case Study of a Flexible NMR Sample Preparation RobotSLAS Technology - Tập 11 - Trang 387-398 - 2006
Miguel A. Maccio, Duncan H. Bell, Dan Davolos
A variety of features used by our Department in the design and integration of
Automation Platforms are presented here. A challenging project for any
automation group is the automation of NMR sample preparation. The dispensing of
highly volatile or viscous solutions into the typical 5 mm ID NMR glass tube,
and the subsequent capping of the tube, presents unique problems. An angled
incremental singl... hiện toàn bộ
Design of an Automated Enhanced-Throughput Platform for Functional Characterization of Positive Allosteric Modulator-Induced Leftward Shifts in Apparent Agonist Potency In VitroSLAS Technology - Tập 17 - Trang 104-115 - 2012
Adam Hendricson, Michele Matchett, Meredith Ferrante, Chris Ferrante, Ed Hunnicutt, Ryan Westphal, Walt Kostich, Yanling Huang, Nelly Masias, Debra Hong, Rob Bertekap, Neil Burford, John Watson, Andrew Alt, Jim Myslik, Litao Zhang, Ron Knox