Abstract In a healthy body, ROS (reactive oxygen species) and antioxidants
remain in balance. When the balance is disrupted towards an overabundance of
ROS, oxidative stress (OS) occurs. OS influences the entire reproductive
lifespan of a woman and even thereafter (i.e. menopause). OS results from an
imbalance between prooxidants (free radical species) and the body's scavenging
ability (antioxidan... hiện toàn bộ
Abstract Ovarian folliculogenesis is regulated by both endocrine and
intraovarian mechanisms that coordinate the processes of oocyte growth and
somatic cell proliferation and differentiation. Within the follicle, paracrine
interactions between the oocyte and surrounding granulosa cells are critical for
normal cell development and function. This review focuses on the role of
paracrine interactions ... hiện toàn bộ
Simon Grill, Corinne Rusterholz, Rosanna Zanetti‐Dällenbach, Sevgi Tercanli, Wolfgang Holzgreve, Sinuhe Hahn, Olav Lapaire
Abstract Preeclampsia is a leading cause of maternal and fetal/neonatal
mortality and morbidity worldwide. The early identification of patients with an
increased risk for preeclampsia is therefore one of the most important goals in
obstetrics. The availability of highly sensitive and specific physiologic and
biochemical markers would allow not only the detection of patients at risk but
also permit... hiện toàn bộ
Yana B Aznaurova, Marat B Zhumataev, Tiffany K Roberts, Alexander M Aliper, Alex A Zhavoronkov
Endometriosis is a common and painful condition affecting women of reproductive
age. While the underlying pathophysiology is still largely unknown, much
advancement has been made in understanding the progression of the disease. In
recent years, a great deal of research has focused on non-invasive diagnostic
tools, such as biomarkers, as well as identification of potential therapeutic
targets. In t... hiện toàn bộ
Abstract Sex determination is the process deciding the sex of a developing
embryo. This is usually determined genetically; however it is a delicate
process, which in many cases can be influenced by environmental factors. The
mechanisms controlling zebrafish sex determination and differentiation are not
known. To date no sex linked genes have been identified in zebrafish and no sex
chromosomes have... hiện toàn bộ
David Barrera, Euclides Avila, Guillermo Hernández, Isabel García Méndez, López González, Ali Halhali, Fernando Larrea, A. Escobedo-Morales, Lorenza Díaz
Tóm tắt Đặt vấn đề Trong thai kỳ, nồng độ calcitriol trong huyết thanh mẹ tăng
cao đáng kể do sự tăng cường đóng góp của thận và nhau thai nhằm đảm bảo nguồn
cung cấp canxi cho thai nhi đang phát triển. Xem xét rằng nhau thai là nơi hoạt
hóa vitamin D, cùng với khả năng linh hoạt và tiềm năng của calcitriol, có khả
năng hormone này tham gia vào sự phát triển và sinh lý của thai nhi/nhau thai.
Tron... hiện toàn bộ