Progress in Biomaterials
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Bone tissue engineering scaffolding: computer-aided scaffolding techniques
Progress in Biomaterials - Tập 3 - Trang 61-102 - 2014
Tissue engineering is essentially a technique for imitating nature. Natural tissues consist of three components: cells, signalling systems (e.g. growth factors) and extracellular matrix (ECM). The ECM forms a scaffold for its cells. Hence, the engineered tissue construct is an artificial scaffold populated with living cells and signalling molecules. A huge effort has been invested in bone tissue e......
Microstructural and in-vitro characteristics of functional calcium silicate topcoat on hydroxyapatite coating for bio-implant applications
Progress in Biomaterials - Tập 11 - Trang 95-108 - 2022
The delayed tissue–implant interactions in metallic implants coated with hydroxyapatite (HA) paved the way for the development of alternative bioactive coatings. In this study, bi-layered functional gradient (HA-CS) coating was formulated by the atmospheric plasma spray (APS) process on Ti6Al4V alloy. The HA layer was applied at the metal interface to ensure long-term stability, while the calcium ......
Chitosan/polyethylene glycol fumarate blend films for wound dressing application: in vitro biocompatibility and biodegradability assays
Progress in Biomaterials - Tập 7 - Trang 143-150 - 2018
Blending is one of the effective approaches in preparing tailored materials with a wide range of properties. Thus, chitosan-based polymers have been fabricated and used as wound dressings since they possess better properties than those of the constituent materials. The objective of this work was to evaluate the biocompatibility and biodegradability of biodegradable blend films based on polyethylen......
The effect of sodium and magnesium ions on the properties of calcium–phosphate biomaterials
Progress in Biomaterials - Tập 8 - Trang 127-136 - 2019
A calcium–phosphate system was obtained by sol–gel method from 0.4 M solutions based on ethyl alcohol, tetraethoxysilane, phosphoric acid, calcium nitrate, and magnesium nitrate, sodium chloride. Compositions with different contents of CaO, Na2O, and MgO were prepared. After maturation of the solutions, heat treatments were applied at 60 °C for 30 min; and followed by 600 °C and 800 °C for 1 h. So......
Designing and fabrication of curcumin loaded PCL/PVA multi-layer nanofibrous electrospun structures as active wound dressing
Progress in Biomaterials - Tập 6 - Trang 39-48 - 2017
Active wound dressings play a significant role in burn and chronic wound treatment. In this study, electrospinning process is used to fabricate a novel three-layer active wound dressing based on ε-polycaprolactone (PCL), polyvinylalcohol (PVA), and curcumin (CU) as a biologically active compound. The main purpose for developing such a system is to control wound exudates, which remains a challenge,......
Stress phase angle regulates differentiation of human adipose-derived stem cells toward endothelial phenotype
Progress in Biomaterials - Tập 7 - Trang 121-131 - 2018
Endothelial cells are subjected to cyclic shear by pulsatile blood flow and pressures due to circumferential stresses. Although most of the researches on this topic have considered the effects of these two biomechanical forces separately or concurrently, few studies have noticed the interaction of these cyclic loadings on endothelial behavior. Negative temporal stress phase angle, defined by the p......
Infrared spectroscopic analysis of restorative composite materials' surfaces and their saline extracts
Progress in Biomaterials - Tập 2 - Trang 1-14 - 2013
This study aims at finding out if multiple attenuated internal reflection-infrared (MAIR-IR) spectroscopic analysis can be used as a tool to differentiate commercial resin composite brands and to find out if different resin composites will have different abilities of leaching materials that are cytotoxic to human gingival fibroblasts (HGFs) Tooth-colored resin fillings have become increasingly pop......
Investigation of the effects of starch on the physical and biological properties of polyacrylamide (PAAm)/starch nanofibers
Progress in Biomaterials - Tập 6 - Trang 85-96 - 2017
Here, we report the development of a new polyacrylamide (PAAm)/starch nanofibers’ blend system and highlight its potential as substrate for efficient enzyme immobilization. PAAm was synthesized and blended with starch. The final blend was then electrospun into nanofibers. The response surface methodology was used to analyze the parameters that control nanofiber’s diameter. Electrospun mat was then......
Recent advances in the formulation of PLGA microparticles for controlled drug delivery
Progress in Biomaterials - Tập 9 - Trang 153-174 - 2020
Polymeric microparticles (MPs) are recognized as very popular carriers to increase the bioavailability and bio-distribution of both lipophilic and hydrophilic drugs. Among different kinds of polymers, poly-(lactic-co-glycolic acid) (PLGA) is one of the most accepted materials for this purpose, because of its biodegradability (due to the presence of ester linkages that are degraded by hydrolysis in......
Design, characterization and in vitro evaluation of thin films enriched by tannic acid complexed by Fe(III) ionsAbstract Materials based on carbohydrate polymers may be used for biomedical application. However, materials based on natural polymers have weak physicochemical properties. Thereby, there is a challenge to improve their properties without initiation of toxicity. The alternative method compared to toxic chemical agents’ addition is the use of metal complexation metho... ...
Progress in Biomaterials - - 2020
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