Progress in Biomaterials

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Fabrication of aortic bioprosthesis by decellularization, fibrin glue coating and re-endothelization: a cell scaffold approach
Progress in Biomaterials - Tập 8 - Trang 197-210 - 2019
Sonal Walawalkar, Shahdab Almelkar
Aortic dysfunctions (aneurysm, aortitis) lead to the most serious conditions related to aortic wall with life-threatening complications. The most common modality of management for such conditions is replacement (diseased part) of aorta by a larger diameter stent (reconstructive vascular surgery) which in itself is a big trial. The most natural way is to use a re-endothelized scaffold. Developing a...... hiện toàn bộ
Fabrication of biocompatible porous scaffolds based on hydroxyapatite/collagen/chitosan composite for restoration of defected maxillofacial mandible bone
Progress in Biomaterials - Tập 8 - Trang 137-154 - 2019
Md Shaifur Rahman, Md Masud Rana, Lucas-Sebastian Spitzhorn, Naznin Akhtar, Md Zahid Hasan, Naiyyum Choudhury, Tanja Fehm, Jan T. Czernuszka, James Adjaye, Sikder M. Asaduzzaman
Fabrication of scaffolds from biomaterials for restoration of defected mandible bone has attained increased attention due to limited accessibility of natural bone for grafting. Hydroxyapatite (Ha), collagen type 1 (Col1) and chitosan (Cs) are widely used biomaterials which could be fabricated as a scaffold to overcome the paucity of bone substitutes. Here, rabbit Col1, shrimp Cs and bovine Ha were...... hiện toàn bộ
Vancomycin-loaded HPMC microparticles embedded within injectable thermosensitive chitosan hydrogels
Progress in Biomaterials - Tập 6 - Trang 49-56 - 2017
M. Mahmoudian, F. Ganji
Antibiotic use is an essential method for the treatment of bacterial infections. In certain cases, antibiotics are not effective because of the distribution problems caused by physiological barriers in the body. Such problems are thought to be minimized by development of sustained release systems which involve implantation of antibiotic loaded polymeric systems directly to the site of infection. I...... hiện toàn bộ
Polyurethane synthesis for vascular application
Progress in Biomaterials - Tập 7 - Trang 269-278 - 2018
Zahra Zaredar, Fahimeh Askari, Parvin Shokrolahi
Three polyurethane formulations were prepared on the basis of siloxane; two formulations contained 1% and 3% of a hydroxyl functionalized polyhedral oligomeric silsesquioxane [POSS (ROH)2] nano-particles (as a co-chain extender) and one was without nano-particle. Structures of the polyurethanes were characterized by FTIR and SEM. The effect of POSS nano-particles on properties of the synthesized P...... hiện toàn bộ
Acceleration in healing of infected full-thickness wound with novel antibacterial γ-AlOOH-based nanocomposites
Progress in Biomaterials - Tập 12 Số 2 - Trang 123-136 - 2023
Parastar, Hilda, Farahpour, Mohammad Reza, Shokri, Rasoul, Jafarirad, Saeed, Kalantari, Mohsen
This study was conducted to synthesize γ-AlOOH (bohemite)-based nanocomposites (NCs) of Au/γ-AlOOH-NC and its functionalized derivative using chitosan (Au/γ-AlOOH/Ctn-NC) and with the help of one-step Mentha piperita. The physicochemical characteristics of the NCs were investigated. In addition, biomedical properties, such as antibacterial activity under in vitro and in vivo conditions, and cell v...... hiện toàn bộ
Polyvinyl alcohol/soy protein isolate nanofibrous patch for wound-healing applications
Progress in Biomaterials - Tập 8 - Trang 185-196 - 2019
Bahareh Khabbaz, Atefeh Solouk, Hamid Mirzadeh
Soy protein isolate (SPI), due to its biocompatibility, biodegradability, abundance and being inexpensive, is a suitable polymer for medical applications. In this study, electrospun nanofibrous mats (ENMs) and casting films (CFs), comprising polyvinyl alcohol (PVA)/SPI, were prepared and compared. Both crosslinked ENMs and CFs physical, chemical, mechanical, and biological properties were investig...... hiện toàn bộ
Comparative of fibroblast and osteoblast cells adhesion on surface modified nanofibrous substrates based on polycaprolactone
Progress in Biomaterials - Tập 5 - Trang 213-222 - 2016
Fereshteh Sharifi, Shiva Irani, Mojgan Zandi, Masoud Soleimani, Seyed Mohammad Atyabi
One of the determinant factors for successful bioengineering is to achieve appropriate nano-topography and three-dimensional substrate. In this research, polycaprolactone (PCL) nano-fibrous mat with different roughness modified with O2 plasma was fabricated via electrospinning. The purpose of this study was to evaluate the effect of plasma modification along with surface nano-topography of mats on...... hiện toàn bộ
Microsphere formulations of ambroxol hydrochloride: influence of Okra (Abelmoschus esculentus) mucilage as a sustained release polymer
Progress in Biomaterials - Tập 9 - Trang 65-80 - 2020
Adenike Okunlola, Michael Ayodele Odeniyi, Matthew Ikhuoria Arhewoh
Ambroxol hydrochloride (AH), a secretion-releasing expectorant, is a good candidate for sustained delivery. Mucilages are biodegradable, inexpensive carriers in microsphere formulations. The study aimed to prepare microspheres of AH using Okra mucilage obtained from pods of Abelmoschus esculentus combined with sodium alginate at various polymer/drug ratios. Okra mucilage was characterized for morp...... hiện toàn bộ
Synthesis of silver nanoparticles utilizing various biological systems: mechanisms and applications—a review
Progress in Biomaterials - Tập 9 - Trang 81-95 - 2020
Divyanshi Garg, Aritri Sarkar, Pooja Chand, Pulkita Bansal, Deepak Gola, Shivangi Sharma, Sukirti Khantwal, Surabhi, Rekha Mehrotra, Nitin Chauhan, Randhir K. Bharti
The evolving technology of nanoparticle synthesis, especially silver nanoparticle (AgNPs) has already been applied in various fields i.e., electronics, optics, catalysis, food, health and environment. With advancement in research, it is possible to develop nanoparticles of various size, shape, morphology, and surface to volume ratio utilizing biological systems. A number of different agents and me...... hiện toàn bộ
Tailoring the gelatin/chitosan electrospun scaffold for application in skin tissue engineering: an in vitro study
Progress in Biomaterials - Tập 7 - Trang 207-218 - 2018
Mohamad Pezeshki-Modaress, Mojgan Zandi, Sarah Rajabi
The nanofibrous structure containing protein and polysaccharide has good potential in tissue engineering. The present work aims to study the role of chitosan in gelatin/chitosan nanofibrous scaffolds fabricated through electrospinning process under optimized condition. The performance of chitosan in gelatin/chitosan nanofibrous scaffolds was evaluated by mechanical tests, scanning electron microsc...... hiện toàn bộ
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