Pharmacology Research and Perspectives
SCIE-ISI SCOPUS (2013-2023)
2052-1707
2052-1707
Anh Quốc
Cơ quản chủ quản: JOHN WILEY & SONS LTD , Wiley-Blackwell Publishing Ltd
Lĩnh vực:
NeurologyPharmacology, Toxicology and Pharmaceutics (miscellaneous)
Các bài báo tiêu biểu
Role of endoplasmic reticulum stress in drug‐induced toxicityAbstract Drug‐induced toxicity is a key issue for public health because some side effects can be severe and life‐threatening. These adverse effects can also be a major concern for the pharmaceutical companies since significant toxicity can lead to the interruption of clinical trials, or the withdrawal of the incriminated drugs from the market. Recent studies suggest... ... hiện toàn bộ
Tập 4 Số 1 - 2016
Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonistAbstract The aim of the study was to investigate the in vitro and in vivo pharmacological profile of cebranopadol, a novel agonist for opioid and nociceptin/orphanin FQ (N/OFQ ) receptors (NOP... hiện toàn bộ
Tập 4 Số 4 - 2016
Pharmacological hypothesis: TPC2 antagonist tetrandrine as a potential therapeutic agent for COVID‐19Abstract More than ten million patients worldwide have been diagnosed with coronavirus disease 19 (COVID‐19) to date (WHO situation report, 1st July 2020). There is no vaccine to prevent infection with the causative organism, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), nor a cure. In the struggle to devise potentially useful therapeutics in record ... ... hiện toàn bộ
Tập 8 Số 5 - 2020
Moderate, chronic ethanol feeding exacerbates carbon tetrachloride–induced hepatic fibrosis via hepatocyte‐specific hypoxia‐inducible factor 1αAbstract The hypoxia‐sensing transcriptional factor HIF 1α is implicated in a variety of hepato‐pathological conditions; however, the contribution of hepatocyte‐derived HIF 1α during progressi... ... hiện toàn bộ
Tập 2 Số 5 - 2014
Hypothesis: Pentoxifylline is a potential cytokine modulator therapeutic in COVID‐19 patientsAbstract We propose a new hypothesis that the established drug pentoxifylline deserves attention as a potential repurposed therapeutic for COVID‐19. Pentoxifylline is an immunomodulator with anti‐inflammatory properties. It is a nonselective phosphodiesterase inhibitor and through Adenosine A2A Receptor‐mediated pathways reduces tumor necrosis factor alpha, interleu... ... hiện toàn bộ
Tập 8 Số 4 - 2020
Extensive protein interactions involving cytochrome P450 3A4: a possible contributor to the formation of a metabolosomeAbstract Cytochrome P450 (CYP ) 3A4 is a membrane protein that catalyzes hydroxylation of endogenous and exogenous substrates. Protein–protein interaction is a crucial factor that regulates the function of enzymes. However, protein–protein interactions involving human hiện toàn bộ
Tập 2 Số 5 - 2014