The new Swedish Prescribed Drug Register—Opportunities for pharmacoepidemiological research and experience from the first six months Tập 16 Số 7 - Trang 726-735 - 2007
Björn Wettermark, Niklas Hammar, C. MichaelFored, Andrejs Leimanis, Petra Otterblad Olausson, Ulf Bergman, Ingemar Persson, Anders Sundström, B Westerholm, Måns Rosén
AbstractPurposeTo describe the content and potentials of the new Swedish
national register on prescribed and dispensed medicines.MethodsThe Swedish
Prescribed Drug Register contains information about age, sex and unique
identifier of the patient as well as the prescriber's profession and practice.
Information regarding drug utilization and expenditures for prescribed drugs in
the entire Swedish po... hiện toàn bộ
Validation of the national health insurance research database with ischemic stroke cases in Taiwan Tập 20 Số 3 - Trang 236-242 - 2011
Ching‐Lan Cheng, Yea‐Huei Kao Yang, Swu‐Jane Lin, Cheng‐Han Lee, Mei‐Jung Lai
AbstractObjectiveThe National Health Insurance Research Database (NHIRD) is
commonly used for pharmacoepidemiological research in Taiwan. This study
evaluated the validity of the database for patients with a principal diagnosis
of ischemic stroke.Study design and methodsThis cross‐sectional study compares
records in the NHIRD with those in one medical center. Patients hospitalized for
ischemic str... hiện toàn bộ
Use of proportional reporting ratios (PRRs) for signal generation from spontaneous adverse drug reaction reports Tập 10 Số 6 - Trang 483-486 - 2001
Stephen Evans, P.J. Waller, Sarah Davis
AbstractBackgroundThe process of generating ‘signals’ of possible unrecognized
hazards from spontaneous adverse drug reaction reporting data has been likened
to looking for a needle in a haystack. However, statistical approaches to the
data have been underutilised.MethodsUsing the UK Yellow Card database, we have
developed and evaluated a statistical aid to signal generation called a
Proportional ... hiện toàn bộ
Quantitative signal detection using spontaneous ADR reporting Tập 18 Số 6 - Trang 427-436 - 2009
Andrew Bate, Stephen Evans
AbstractQuantitative methods are increasingly used to analyse spontaneous
reports. We describe the core concepts behind the most common methods, the
proportional reporting ratio (PRR), reporting odds ratio (ROR), information
component (IC) and empirical Bayes geometric mean (EBGM). We discuss the role of
Bayesian shrinkage in screening spontaneous reports, the importance of changes
over time in sc... hiện toàn bộ
One‐to‐many propensity score matching in cohort studies Tập 21 Số S2 - Trang 69-80 - 2012
Jeremy A. Rassen, Abhi Shelat, Jessica A. Myers, Robert J. Glynn, Kenneth J. Rothman, Sebastian Schneeweiß
ABSTRACTBackgroundAmong the large number of cohort studies that employ
propensity score matching, most match patients 1:1. Increasing the matching
ratio is thought to improve precision but may come with a trade‐off with respect
to bias.ObjectiveTo evaluate several methods of propensity score matching in
cohort studies through simulation and empirical analyses.MethodsWe simulated
cohorts of 20 000 ... hiện toàn bộ
A systematic review of validated methods for identifying atrial fibrillation using administrative data Tập 21 Số S1 - Trang 141-147 - 2012
Paul N. Jensen, Karin Johnson, James S. Floyd, Susan R. Heckbert, Ryan M. Carnahan, Sascha Dublin
ABSTRACTPurposeThe objectives of this study were to characterize the validity of
algorithms to identify AF from electronic health data through a systematic
review of the literature and to identify gaps needing further
research.MethodsTwo reviewers examined publications during 1997–2008 that
identified patients with atrial fibrillation (AF) from electronic health data
and provided validation inform... hiện toàn bộ
Estimates of acetaminophen (paracetomal)‐associated overdoses in the United States Tập 15 Số 6 - Trang 398-405 - 2006
Parivash Nourjah, Syed Rizwanuddin Ahmad, Claudia Karwoski, Mary E. Willy
AbstractObjectiveTo estimate the number of acetaminophen‐associated overdoses in
the United States and identify possible risk factors for intervention.MethodsThe
investigators obtained estimates of acetaminophen‐associated overdoses using
different national databases. Two emergency room databases, a hospital discharge
database, a national mortality file, and a poison surveillance database were
use... hiện toàn bộ
A systematic review of validated methods for identifying venous thromboembolism using administrative and claims data Tập 21 Số S1 - Trang 154-162 - 2012
Leonardo Tamariz, Thomas Harkins, Vinit Nair
ABSTRACTBackgroundVenous thromboembolism (VTE) is a serious complication. Large
claims databases can potentially identify the effects that medications have on
VTE. The purpose of this study is to evaluate the evidence supporting the
validity of VTE codes.MethodsA search of MEDLINE database is supplemented by
manual searches of bibliographies of key relevant articles. We selected all
studies in whi... hiện toàn bộ