Pflügers Archiv
1432-2013
0031-6768
Cơ quản chủ quản: Springer Heidelberg , Springer Verlag
Lĩnh vực:
PhysiologyClinical BiochemistryPhysiology (medical)
Phân tích ảnh hưởng
Thông tin về tạp chí
Các bài báo tiêu biểu
Ueber den Einfluss der Nerven auf die Erweiterung der Pupille bei Fröschen
Tập 38 Số 1 - Trang 219-273 - 1886
Versuche über die Wirkung von Entladungsschlägen auf Blut und auf halbdurchlässige Membranen
Tập 91 - Trang 164-188 - 1902
Die quantitative Analyse des Harnstoffs im menschlichen Harne durch Kochen mit ätzendem Alkali
- 1889
Objektive Registrierung der Hämolyse mit Sperrschichtphotozellen
Tập 231 - Trang 135-139 - 1933
Es wird ein einfaches Verfahren zur Messung und Registrierung der Hämolyse mit Sperrschichtphotozellen beschrieben und auf die weitere vielseitige Anwendbarkeit derartiger, ohne Verstärkung benutzbarer Zellen hingewiesen.
Properties of a Ca2+ activated K+ conductance in /Helix neurones investigated by intracellular Ca2+ ionophoresis
Tập 393 - Trang 248-253 - 1982
Facilitation of acetylcholine release from cardiac parasympathetic nerve endings effect of stimulation pattern and Mn ions
Tập 391 - Trang 105-111 - 1981
The influence of the stimulus interval and the effect of Mn ions on facilitation of acetylcholine (ACh) release from parasympathetic nerve terminals were studied in quiescent guinea-pig auricles by electrophysiological methods. A maximum facilitation occurs at intervals of about 50 ms. The half time of decay of facilitation after a conditioning stimulus is about 500 ms. When conditioning trains of stimuli were applied, a second much longer lasting compoenent of facilitation was found (t
1/2≅4s). Mn ions, after exerting an inhibitory effect, cause an increase of ACh release, the development of which is dependent on frequent stimulation of the nerve fibres. This potentiation is accompanied by an apparent loss of facilitation. A further increase in ACh release occurs when superfusion is changed from Mn containing to normal Tyrode's solution. The decay to the control level displays a half time of about 20 min and can also be accelerated by frequent stimulation of the parasympathetic nerve fibres. It is suggested that Mn ions not only inhibit a Ca inward current but may also act on intracelllular Ca2+ binding sites in the nerve terminal. When these sites are blocked even a reduced Ca influx can be more effective in the process of transmitter release.