Temperature regulation in man ? A theoretical study

J. A. J. Stolwijk1, James D. Hardy1
1John B. Pierce Foundation Laboratory and Dept. of Physiology, Yale University School of Medicine, New Haven,

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Allwood, M. J., and H. S. Burry: The effect of local temperature on blood flow in the human foot. J. Physiol. (Lond.) 124, 345 (1954).

Andersen, H. T., H. T. Hammel, and J. D. Hardy: Modifications of the febrile response to pyrogens by hypothalamic heating and cooling in the unanesthetized dog. Acta physiol. scand. 53, 247?254 (1961).

Aschoff, V. J., u. R. Wever: Kern und Schale im Wärmehaushalt des Menschen. Naturwissenschaften 20, 477 (1958).

Atzler, E., u. F. Richter: Die spezifische Wärme des Blutes und des Serums unter besonderer Berücksichtigung der Methodik. Biochem. Z. 100, 193 (1919).

Barbour, H. G.: Die Wirkung unmittelbarer Erwärmung und Abkühlung der Wärmezentren auf die Körpertemperatur. Naunyn-Schmiedebergs Arch. exp. Path. Pharmak. 70, 1 (1912).

Bazett, H. C., and W. G. Penfield: A study of the Sherrington decerebrate animal in the chronic as well as in the acute condition. Brain 45, 185 (1922).

Behnke, A. R., and T. L. Willmon: Cutaneous diffusion of helium in relation to peripheral blood flow and absorption of atmospheric nitrogen through the skin. Amer. J. Physiol. 131, 627 (1941).

Benzinger, T. H.: On physical heat regulation and the sense of temperature in man. Proc. nat. Acad. Sci. (Wash.) 45, 645 (1959).

?? The Human Thermostat. In: Temperature?Its Measurement and Control in Science and Industry. Part III, Chapt. 56, p. 637. New York: Reinhold Publ. Corp. 1963.

Bishop, T. M., K. W. Donald, S. H. Taylor, and P. N. Wormald: Changes in arterial-hepatic venous oxygen content differences during and after supine leg exercise. J. Physiol. (Lond.) 137, 309 (1957).

Bligh, J.: Localization of the thermal stimulus to polypnoea. J. Physiol. (Lond.) 135, 14 (1956).

Bradley, S. E.: The hepatic circulation. In: Handbook of Physiology, Circulation, Vol. II, Section 2. Washington: Am. Physiological Society 1963.

Bucht, H., T. E. Eliasch, A. Holmgrew, B. Josephson, and L. Wesko: The effect of exercise in the recumbent position on the renal circulation and sodium excretion in normal individuals. Acta. physiol. scand. 28, 95 (1953).

Burgh, G. E.: Digital Plethysmography. New York: Grune and Shatton 1954.

Burton, A. C.: The application of the theory of heat flow to the study of energy metabolism. J. Nutr. 7, 497 (1934).

?? The operating characteristics of the human thermoregulatory system. In: Temperature, its Measurement and Control in Science and Industry. Am. Inst. Physics. New York: Reinhold Publ. Corp. 1941.

Coleman, B., A. B. Hertzman, L. E. D'Agrosa, and F. Flath: Impedance measurements of cardiac output during moderate heat exposure. Report AMRL-TR-66-5 Aero-Space Medical Research Laboratories, Wright-Patterson Air Force Base, Ohio: 1966.

Cooper, K. E., O. G. Edholm, and R. F. Mottram: The blood flow in skin and muscle of the human forearm. J. Physiol. (Lond.) 128, 258 (1955).

Cooper, T., W. C. Randall, and A. B. Hertzman: Vascular convection of heat from active muscle to overlying skin. J. appl. Physiol. 14, 207 (1959).

Crosbie, R. J., J. D. Hardy, and E. Fessenden: Electrical Analog Simulation of Temperature Regulation in Man. In: Temperature, its Measurement and Control in Science and Industry, Part III, Chapt. 55, p. 627. New York: Reinhold Publ. Corp. 1963.

DuBois, E. F.: Basal Metabolism in Health and Disease. Philadelphia: Lea and Ferbiger 1936.

Edholm, O. G., R. H. Fox, and R. K. MacPherson: The effect of body heating on the circulation in skin and muscle. J. Physiol. (Lond.) 134, 612 (1956).

Gardner, E., D. J. Gray, and R. O'Rahilly: Anatomy. Philadelphia: W. B. Saunders Co. 1960.

Goetz, R. H.: Rate of control of blood flow through the skin of lower extremities. Amer. Heart J. 31, 146 (1946).

Golenhofen, K., H. Hensel, and G. Hildebrandt: Durchblutungsmessung mit Wärmeleitungselementen. Stuttgart: G. Thieme 1963.

Greenfield, A. D. M.: The Circulation Through the Skin. In: Handbook of Physiology, Section 2, Volume II, pp. 1325?1351. Washington: Am. Physiol. Soc. 1963.

Guyton, A. C.: Circulatory Physiology: Cardiac Output and its Regulation. Philadelphia: W. B. Saunders Co. 1963.

Hall, V. E., R. T. Grant, and W. J. Whalen: The influence of magnesium and pyrogens on temperature regulation. WADC Tech. Rept. No. 6682: III (1951).

Hammel, H. T., R. W. Elsner, D. H. LeMessurier, and H. T. Andersen: Thermal and metabolic responses of the Australian Aborigine exposed to moderate cold in summer. J. appl. Physiol. 14, 605 (1959).

??, and S. B. Strømme: Temperature regulation by hypothalamic proportional control with adjustable set point. J. appl. Physiol. 18, 1146?1154 (1963).

Hammouda, M.: The central and the reflex mechanism of panting. J. Physiol. (London). 77, 319 (1933).

Hardy, J. D.: Control of heat loss and heat production in physiologic temperature regulation. Harvey Lec. Ser. XLIX, 242 (1953?1954).

??, and E. F. DuBois: Basal metabolism, Radiation, convection and, vaporization at temperatures of 22°C to 35°C. J. Nutr. 15, 477 (1938).

??, and H. T. Hammel: Control system in Physiological Temperature Regulation. In: Temperature, its Measurement and Control in Science and Industry. Part III. Chapt. 54, p. 613. New York: Reinhold Publ. Corp. 1963.

??, and K. Sutherland: Temperature sensitive neurons in the dog's hypothalamus. J. Physiol. (Lond.) 175, 242?253 (1964).

??, and G. F. Soderstrom: Heat loss from the nude body and peripheral blood flow at temperatures of 22°C to 35°C. J. Nutr. 16, 493 (1938).

??, and J. A. J. Stolwijk: Partitional calorimetric studies of man during exposures to thermal transients. J. appl. Physiol. (in press) (1966).

Hemmingway, A.: Effects of heating hypothalamus of dogs by diathermy. J. Neurophysiol. 3, 328 (1940).

Hertzman, A. B.: Vasomotor regulation of cutaneous circulation. Physiol. Rev. 39, 280 (1959).

??, and W. C. Randall: Regional differences in the basal and maximal rates of blood flow in the skin. J. appl. Physiol. 1, 234 (1948).

?? ??, and C. N. Peiss: The cutaneous vascular responses to rising environmental temperature. U.S.A.F. Techn. Report 6680 part 6, Wright Air Development Center, Ohio. 1951.

Keller, A. D., and W. K. Hare: The hypothalamus and heat regulation. Proc. Soc. exp. Biol. (N.Y.) 29, 1069 (1932).

??, and E. B. McClaskey: Localization, by the brain slicing method, of the level or levels of the cephalic brain stem upon which effective heat dissipation is dependent. Amer. J. phys. Med. 43, 181 (1964).

Kramer, K., and W. Quensel: Untersuchungen über den Muskelstoff während der tetanischen Kontraktion. Pflügers Arch. ges. Physiol. 239, 620 (1937).

Liebermeister, C.: Untersuchungen über die quantitative Veränderung der Kohlensäureproduktion beim Menschen. Dtsch. Arch. klin. Med. 8, 153 (1871).

Mendlowitz, M.: The digital circulation. New York: Greene and Stratton 1954.

Nakayama, T. H., J. S. Eisenman, and J. D. Hardy: Single unit activity of anterior hypothalamus during local heating. Science 134, 560?561 (1961).

Ott, T.: Heat center in the brain. J. nerv. ment. Dis. 14, 152 (1887).

Park, C. R., and E. D. Palmes: The regulation of body temperature during fever. U.S. Army Med. Research Lab., Project No. 6-64-12-06, Fort Knox, Ky. Oct. 1948.

Piironen, P., and E. Äikäs: Temperature of the human body during rapid alternating heating and cooling. Tech. Report No. AF-EOAR-63-113, Institute Occupational Health, Helsinki, Finland 1964.

Richet, C.: Die Beziehung des Gehirns zur Körperwärme und zum Fieber. Pflügers Arch. ges. Physiol. 37, 624 (1885).

Roddie, I. C., and J. T. Shepherd: The blood flow through the hand during local heating, release of sympathetic vasomotor tone by indirect heating and a combination of both. J. Physiol. (Lond.) 131, 657 (1956).

Robinson, S., F. R. Meyer, J. L. Newton, C. H. Ts'ao, and L. O. Holgersen: Relations between sweating, cutaneous blood flow, and body temperature in work. J. appl. Physiol. 20, 575 (1965).

Rubner, M.: Die Gesetze des Energieverbrauchs bei der Ernährung. Leipzig: F. Deuticke 1902.

Rushmer, R. F.: Constancy of stroke volume in ventricular response to exertion. Amer. J. Physiol. 196, 745 (1959).

?? Postural effects on the baselines of ventricular performance. Circulation 20, 897 (1959).

Schaeffer, J. P., and Morris Shuman: Anatomy. Philadelphia: The Blakiston Co. 1942.

Scheinberg, P., L. I. Blackburn, M. Rich, and M. Shaw: Effects of vigorous physical exercise on cerebral circulation and metabolism. Amer. J. Med. 16, 549 (1954).

Schroder, J., and E. Voridis: Über Innentemperatur, Wärmedurchgangszahl und Spontanrhythmik der Durchblutung der menschlichen Hand. Pflügers Arch. ges. Physiol. 261, 550 (1955).

Selkurt, E. E.: The renal circulation. In: Handbook of Physiology: Circulation Vol. II, Sect. II. Washington: American Physiological Society 1963.

Smith, P. E., and E. W. James II: Human responses to heat Stress. Arch. environm. Hlth 9, 332 (1964).

Stolwijk, J. A. J., and J. D. Hardy: Partitional calorimetric studies of response of man to thermal transients. J. appl. Physiol. 21, 3, 967 (1966).

Thauer, R.: Der nervöse Mechanismus der chemischen Temperaturregulation des Warmblüters. Naturwissenschaften 51, 73 (1964).

??, u. G. Peters: Wärmeregulation nach operativer Ausschaltung des Wärmezentrums. Pflügers Arch. ges. Physiol. 239, 483 (1937).

Villablanca, J., and R. D. Myers: Fever produced by micro injection of typhoid vaccine into hypothalamus of cats. Amer. J. Physiol. 208, 703 (1965).

Wilmer, H. A.: Changes in structural components of human body from six lunar months to maturity. Proc. Soc. exp. Biol. (N.Y.) 53, 545 (1940).

Winslow, C.-E. A., L. P. Herrington, and A. P. Gagge: Physiological reactions of the human body to varying environmental temperatures. Amer. J. Physiol. 120, 1 (1937).

Wissler, E. H.: An analysis of factors affecting temperature levels in the nude human. In: Temperature, its Measurement and Control in Science and Industry, Part III, Chap. 53, p. 603. New York: Reinhold Publ. Corp. 1963.

Wyndham, C. J., and A. R. Atkins: Approach to solution of human biothermal problem with aid of an analog computer. Paper No. 27, 3rd Int. Conference on Medical Electronics, 1960.

??, and D. K. C. MacDonald: Examination of use of heat-exchange equations for determining changes in body temperature. J. appl. Physiol. 5, 299 (1952).