Versatile piezoelectric driver for cell puncturePflügers Archiv - - 1980
Michael Fromm, Paul Weskamp, Ulrich Hegel
A simple and versatile tool facilitating micropuncture of small cells is described which utilizes a commercial piezoelectric element made from a stacked column of monomorph ceramic discs. The device is able to advance complete input stage-electrode-assemblies with high speed and can be used in combination with conventional micromanipulators. Advancing characteristics as recorded optically at high ...... hiện toàn bộ
Antagonistic changes of blood flow and sympathetic activity in different vascular beds following central thermal stimulationPflügers Archiv - Tập 319 - Trang 146-161 - 1970
R. Kullmann, W. Schönung, E. Simon
Blood flow in arteries mainly supplying cutaneous, muscular or intestinal vascular regions and aortic blood flow were measured with an electromagnetic flowmeter in anesthetized dogs immobilized with succinyl choline. Up to 3 flows were recorded simultaneously with mean arterial pressure during thermal stimulation of the spinal cord at constant, neutral ambient air temperatures. In conformity with ...... hiện toàn bộ
Effect of bicarbonate on potassium conductance of isolated perfused rat pancreatic ductsPflügers Archiv - Tập 419 - Trang 76-83 - 1991
I. Novak, R. Greger
The aim of this study was to investigate the role of the K+ conductance in unstimulated and stimulated pancreatic ducts and to see how it is affected by provision of exogenous HCO
3
−
/CO2. For this purpose we have applied electrophysiological techniques to perfused pancreatic ducts, which were dissected from rat pancreas. The basolateral membran...... hiện toàn bộ
The PPAR-gamma-binding sequence Pal3 is necessary for basal but dispensable for high-fat diet regulated human renin expression in the kidneyPflügers Archiv - Tập 469 - Trang 1349-1357 - 2017
Peter Lachmann, Jenny Selbmann, Linda Hickmann, Bernd Hohenstein, Christian Hugo, Vladimir T. Todorov
We reported earlier that PPAR-gamma regulates renin transcription through a human-specific atypical binding sequence termed hRen-Pal3. Here we developed a mouse model to investigate the functional relevance of the hRen-Pal3 sequence in vivo since it might be responsible for the increased renin production in obesity and thus for the development of accompanying arterial hypertension. We used bacteri...... hiện toàn bộ
Cerebrospinal fluid sodium concentration and osmosensitive sites related to arterial pressure in anaesthetized ratsPflügers Archiv - Tập 431 - Trang 807-813 - 1996
Munetaka Hirose, Hiroshi Nose, Mian Chen, Takiko Yawata
Intracerebroventricular injection of hypertonic saline induces experimental hypertension. To measure [Na] in the vicinity of osmosensitive sites, we continuously measured [Na] in cerebrospinal fluid ([Na]csf) in the lateral ventricle (LV, n = 6), in the third ventricle (V3, n = 6) and in the medial preoptic nucleus (MPO, n = 6) ([Na]MPO) with a Na-sensitive electrode together with mean arterial pr...... hiện toàn bộ
Voltage-dependent changes in specific membrane capacitance caused by prestin, the outer hair cell lateral membrane motorPflügers Archiv - Tập 444 - Trang 99-106 - 2014
Joseph Santos-Sacchi, Enrique Navarrete
In the outer hair cell (OHC), membrane capacitance principally derives from two components – that associated with lateral membrane sensor/motor charge movement, and that proportional to the membrane surface area (C
sa). We used measures of membrane capacitance to test a model hypothesis that OHC lateral membrane molecular motors, recently identified as the protein prestin, fluctua...... hiện toàn bộ