Paediatric Anaesthesia
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Ropivacaine in neonates and infants: a population pharmacokinetic evaluation following single caudal blockSummary Background : The aims of this study were to evaluate pharmacokinetics, efficacy and safety of ropivacaine in infants aged 0–12 months following a single caudal injection.Methods : Term ASA I–III patients, scheduled for surgery, with a body weight of ≥2500 g received a caudal block with ropivacain...
Paediatric Anaesthesia - Tập 14 Số 9 - Trang 724-732 - 2004
Pharmacokinetics and analgesic effect of ropivacaine following ilioinguinal/iliohypogastric nerve block in children Background: The aim was to investigate the efficacy, tolerance and pharmacokinetics of ropivavcaine when administered for ilioinguinal/iliohypogastric block in children. Methods: We examined the pharmacokinetics and analgesic efficacy after ilioinguinal/iliohypogastric nerve block with 3 mg·kg−1 ro... ...
Paediatric Anaesthesia - Tập 11 Số 4 - Trang 415-420 - 2001
Management of procedural pain in NICUs remains problematic
Paediatric Anaesthesia - Tập 15 Số 11 - Trang 909-912 - 2005
Intraoperative low‐dose S‐ketamine has no preventive effects on postoperative pain and morphine consumption after major urological surgery in childrenSummary Background : Clinical studies suggest low‐dose ketamine may have preemptive effects on postoperative pain in adults. The objective of this study was to determine whether intraoperative low‐dose S‐ketamine reduces postoperative pain and morphine consumption in children undergoing major urological surgery.Mate...
Paediatric Anaesthesia - Tập 15 Số 6 - Trang 484-490 - 2005
Tramadol vs morphine during adenotonsillectomy for obstructive sleep apnea in childrenSummary Background: Optimal analgesia for children undergoing adenotonsillectomy for obstructive sleep apnea (OSA) is controversial. Tramadol may represent a superior choice over morphine in this group, with a potential to cause less postoperative sedation and respiratory depression. Optimal perioperative analgesia may allow expensive and tim...
Paediatric Anaesthesia - Tập 16 Số 6 - Trang 648-653 - 2006
Scaling for size: some implications for paediatric anaesthesia dosing
Paediatric Anaesthesia - Tập 12 Số 3 - Trang 205-219 - 2002
Rofecoxib administration to paediatric patients undergoing adenotonsillectomySummary Background : Rofecoxib is a selective COX‐2 inhibitor that does not interfere with platelet function and is associated with fewer bleeding complications than other nonsteroidal anti‐inflammatory agents (NSAIDs). Our aims were to evaluate the safety and the efficacy of rofecoxib administration to paediatric patients undergoing adenotons...
Paediatric Anaesthesia - Tập 14 Số 7 - Trang 579-583 - 2004
Diclofenac and metabolite pharmacokinetics in childrenSummary Background : Data concerning metabolism of diclofenac in children are limited to intravenous and enteric coated oral formulations. There are no data examining diclofenac or its hydroxyl metabolite pharmacokinetics after rectal administration in children.Methods : Infants (n...
Paediatric Anaesthesia - Tập 14 Số 6 - Trang 443-451 - 2004
Getting the best from pediatric pharmacokinetic data
Paediatric Anaesthesia - Tập 14 Số 9 - Trang 713-715 - 2004
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