Tramadol vs morphine during adenotonsillectomy for obstructive sleep apnea in children

Paediatric Anaesthesia - Tập 16 Số 6 - Trang 648-653 - 2006
Bruce Hullett1, NEIL A. CHAMBERS1, Elaine M. Pascoe1, Chris Johnson1
1Department of Anaesthesia and Pain Management, Princess Margaret Hospital for Children, Perth, WA, Australia

Tóm tắt

SummaryBackground:  Optimal analgesia for children undergoing adenotonsillectomy for obstructive sleep apnea (OSA) is controversial. Tramadol may represent a superior choice over morphine in this group, with a potential to cause less postoperative sedation and respiratory depression. Optimal perioperative analgesia may allow expensive and time‐consuming preoperative work‐up and postoperative monitoring to be rationalized.Methods:  Sixty‐six children were randomized to receive either perioperative tramadol or morphine in this double blinded, prospective, controlled trial. Postoperative sedation, pain, respiratory events, and vomiting were then compared between groups.Results:  There was no significant difference between the two groups in sedation scores 1 h after arrival in recovery (P = 0.24) or at any other time up to 6 h postoperation. There was also no evidence of a difference between the groups in pain scores up to 6 h postoperation. There were fewer episodes of postoperative desaturation (<94%) in the tramadol group up to 3 h postoperation, with 26% fewer episodes in the tramadol group during the second hour postoperation (P = 0.02). Overall, there was a trend toward fewer desaturation episodes in the tramadol group.Conclusions:  Tramadol may be a suitable drug for children undergoing adenotonsillectomy for OSA. Further work is required to investigate this.

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Paediatric Anaesthesia

Tập 16 Số 6

648-653

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