Obstetrics & Gynecology
0029-7844
Cơ quản chủ quản: LIPPINCOTT WILLIAMS & WILKINS , Lippincott Williams and Wilkins Ltd.
Lĩnh vực:
Obstetrics and Gynecology
Phân tích ảnh hưởng
Thông tin về tạp chí
Các bài báo tiêu biểu
Age-Specific Levels for Basal Follicle-Stimulating Hormone Assessment of Ovarian Function
Tập 109 Số 6 - Trang 1404-1410 - 2007
Placental pathology, antiphospholipid antibodies, and pregnancy outcome in recurrent miscarriage patients
Tập 101 - Trang 258-263 - 2003
Letrozole Compared With Clomiphene Citrate for Polycystic Ovarian Syndrome OBJECTIVE: To estimate the effect of letrozole and clomiphene citrate in women with infertility and polycystic ovarian syndrome (PCOS). METHODS OF STUDY SELECTION: MEDLINE through PubMed, Web of Science, EMBASE, Cochrane Library, and ClinicalTrials.gov were searched for relevant studies from inception to February 1, 2022. Two reviewers retrieved, filtered, and extracted data independently using the bibliographic software EndNote X9 and Excel workbook. We included randomized controlled trials (RCTs) reporting ovulation induction outcomes in women with infertility and PCOS treated with either letrozole or clomiphene citrate followed by timed intercourse or intrauterine insemination. The data were merged into a mean difference or risk ratio (RR) with 95% CI, depending on variable types. TABULATION, INTEGRATION, AND RESULTS: Data collection and organization were conducted in accordance with the 2020 PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analyses) statement. Twenty-nine RCTs were eligible, which included 3,952 women and 7,633 ovulation induction cycles. We acquired evidence from 22 RCTs for the ovulation rate, 28 RCTs for the clinical pregnancy rate, and eight RCTs for live-birth rate. Pooled analysis indicated that letrozole treatment prevailed against clomiphene citrate in ovulation rate (RR 1.14, 95% CI 1.06–1.21,P <.001), clinical pregnancy rate (RR 1.48, 95% CI 1.34–1.63,P <.001), and live-birth rate (RR 1.49, 95% CI 1.27–1.74,P <.001). CONCLUSIONS: Letrozole was associated with improved ovulation, pregnancy, and live-birth rates compared with clomiphene citrate. We recommend letrozole over clomiphene citrate as an ovulation induction drug in women with infertility and PCOS, although the quality of the evidence is mixed. SYSTEMATIC REVIEW REGISTRATION: PROSPERO, CRD42022308777.
Tập 141 Số 3 - Trang 523-534 - 2023
Severity of 2009 Pandemic Influenza A (H1N1) Virus Infection in Pregnant Women
Tập 115 Số 4 - Trang 717-726 - 2010
Prone Positioning for Pregnant Women With Hypoxemia Due to Coronavirus Disease 2019 (COVID-19) The coronavirus disease 2019 (COVID-19) pandemic has prompted expanded use of prone positioning for refractory hypoxemia. Clinical trials have demonstrated beneficial effects of early prone positioning for acute respiratory distress syndrome (ARDS), including decreased mortality. However, pregnant women were excluded from these trials. To address the need for low-cost, low-harm interventions in the face of a widespread viral syndrome wherein hypoxemia predominates, we developed an algorithm for prone positioning of both intubated and nonintubated pregnant women. This algorithm may be appropriate for a wide spectrum of hypoxemia severity among pregnant women. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is responsible for the clinical manifestations of COVID-19. This syndrome can manifest as severe pneumonia complicated by hypoxemia and ARDS. Given the current global COVID-19 pandemic, with a large number of ARDS cases, there is renewed interest in the use of prone positioning to improve oxygenation in moderate or severe hypoxemia. Among the populations who can benefit from prone positioning are pregnant women experiencing severe respiratory distress, as long as the physiologic changes and risks of pregnancy are taken into account.
Tập 136 Số 2 - Trang 259-261 - 2020
Rates of Maternal and Perinatal Mortality and Vertical Transmission in Pregnancies Complicated by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Co-V-2) Infection
OBJECTIVE:
To ascertain the frequency of maternal and neonatal complications, as well as maternal disease severity, in pregnancies affected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
DATA SOURCES:
MEDLINE, Ovid, ClinicalTrials.gov, MedRxiv, and Scopus were searched from their inception until April 29, 2020. The analysis was limited to reports with at least 10 pregnant patients with SARS-CoV-2 infection that reported on maternal and neonatal outcomes.
METHODS OF STUDY SELECTION:
Inclusion criteria were pregnant women with a confirmed diagnosis of SARS-CoV-2 infection. A systematic search of the selected databases was performed by implementing a strategy that included the MeSH terms, key words, and word variants for “coronavirus,” “SARS-CoV-2,” “COVID-19,” and “pregnancy.r The primary outcomes were maternal admission to the intensive care unit (ICU), critical disease, and death. Secondary outcomes included rate of preterm birth, cesarean delivery, vertical transmission, and neonatal death. Categorical variables were expressed as percentages with number of cases and 95% CIs.
TABULATION, INTEGRATION, AND RESULTS:
Of the 99 articles identified, 13 included 538 pregnancies complicated by SARS-CoV-2 infection, with reported outcomes on 435 (80.9%) deliveries. Maternal ICU admission occurred in 3.0% of cases (8/263, 95% CI 1.6–5.9) and maternal critical disease in 1.4% (3/209, 95% CI 0.5–4.1). No maternal deaths were reported (0/348, 95% CI 0.0–1.1). The preterm birth rate was 20.1% (57/284, 95% CI 15.8–25.1), the cesarean delivery rate was 84.7% (332/392, 95% CI 80.8–87.9), the vertical transmission rate was 0.0% (0/310, 95% CI 0.0–1.2), and the neonatal death rate was 0.3% (1/313, 95% CI 0.1–1.8).
CONCLUSION:
With data from early in the pandemic, it is reassuring that there are low rates of maternal and neonatal mortality and vertical transmission with SARS-CoV-2. The preterm birth rate of 20% and the cesarean delivery rate exceeding 80% seems related to geographic practice patterns.
SYSTEMATIC REVIEW REGISTRATION:
PROSPERO, CRD42020181497.
Tập 136 Số 2 - Trang 303-312 - 2020
Using Middle Cerebral Artery Peak Systolic Velocity to Time In Utero Transfusions in Fetomaternal Hemorrhage
Tập 115 Số 5 - Trang 1036-1038 - 2010