Neurological Sciences
1590-3478
Cơ quản chủ quản: Springer-Verlag Italia Srl
Lĩnh vực:
Medicine (miscellaneous)Neurology (clinical)Psychiatry and Mental HealthDermatology
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Các bài báo tiêu biểu
Revolving door phenomenon in a headache center among patients with chronic headache and medication overuse
Tập 39 - Trang 161-162 - 2018
Chronic daily headache: risk factors and pathogenetic considerations
Tập 27 - Trang s168-s173 - 2006
Chronic daily headache (CDH) is a major clinical concern, although it is still plagued by difficulties with classification and definitions. CDH usually evolves from an episodic headache, mainly migraine. Drug overuse and other somatic or psychological traits are considered risk factors for CDH. The neurobiology underlying this clinical evolution is incompletely understood. There is evidence of a progressive dysfunction of central pain systems in some individuals probably genetically predisposed.
Diagnostics of autoimmune encephalitis associated with antibodies against neuronal surface antigens
Tập 38 - Trang 225-229 - 2017
This document presents the guidelines for testing antibodies against neuronal surface antigens that have been developed following a consensus process built on questionnaire-based surveys, internet contacts, and discussions at workshops of the sponsoring Italian Association of Neuroimmunology (AINI) congresses. Essential clinical information on autoimmune encephalitis associated with antibodies against neuronal surface antigens, indications and limits of testing for such antibodies, instructions for result interpretation, and an agreed laboratory protocol (Appendix A) are reported for the communicative community of neurologists and clinical pathologists.
Myelin oligodendrocyte glycoprotein antibody-associated disease preceding primary central nervous system lymphoma: causality or coincidence?
Tập 44 - Trang 3711-3715 - 2023
Primary
central nervous system lymphoma (PCNSL) is a rare extranodal lymphomatous malignancy that affects the brain, spinal cord, leptomeninges, or eyes, in the absence of systemic diffusion. Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is a newly identified benign immune-mediated CNS inflammatory disorder with specific anti-MOG antibody seropositivity. These two seemingly unrelated nosological entities both have abundant clinical and radiological manifestations, and whether there is a potential link between them is unclear. We describe a 49-year-old man who presented progressive headache, dizziness, and unsteady gait with multifocal scattered T2 hyperintensities with contrast enhancement. The serum anti-MOG antibody test was positive, and a brain biopsy showed inflammatory infiltration. Initially, he was diagnosed with MOGAD and his condition improved after corticosteroid therapy. The patient relapsed with exacerbation of symptoms and neuroimaging showed new mass-forming lesions four months later. A second brain biopsy confirmed PCNSL. This is the first report of histologically confirmed successive MOGAD and PCNSL. Our case broadens the phenotypic spectrum of sentinel lesions in PCNSL. Though rare, PCNSL should be considered in patients diagnosed with benign CNS inflammatory disorder and responding well to steroid treatment when their clinical symptoms worsen and the imaging deteriorates. A timely biopsy is critical for accurate diagnosis and appropriate therapy.
Combination of olfactory aplasia and congenital ocular motor apraxia: a previously unreported association
Tập 40 - Trang 2419-2421 - 2019
Vitamin D3 might improve headache characteristics and protect against inflammation in migraine: a randomized clinical trial
Tập 41 Số 5 - Trang 1183-1192 - 2020