Multiple Sclerosis Journal
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Trichuris suis ova therapy in relapsing multiple sclerosis is safe but without signals of beneficial effectBackground: An observational study has suggested that relapsing–remitting multiple sclerosis patients with helminth infections have lower disease activity and progression than uninfected multiple sclerosis patients. Objective: To evaluate the safety and efficacy on MRI activity of treatment wi... ... hiện toàn bộ
Multiple Sclerosis Journal - Tập 21 Số 13 - Trang 1723-1729 - 2015
Anti-Epstein–Barr virus antibodies as serological markers of multiple sclerosis: a prospective study among United States military personnel Background: Elevated Epstein–Barr virus (EBV) antibody titers are risk factors for multiple sclerosis (MS), but the strength and consistency of this association are not well characterized. Objectives: The objectives of this study were to determine whether this association is confounded by vitamin D or modified by gender or race, and the usefulness of EBV nuclear antigen ... ... hiện toàn bộ
Multiple Sclerosis Journal - Tập 17 Số 10 - Trang 1185-1193 - 2011
Preventing brain atrophy should be the gold standard of effective therapy in multiple sclerosis (after the first year of treatment): Commentary
Multiple Sclerosis Journal - Tập 19 Số 8 - Trang 1007-1008 - 2013
Changes of brain resting state functional connectivity predict the persistence of cognitive rehabilitation effects in patients with multiple sclerosisObjective: We investigated whether the efficacy of 12-week cognitive rehabilitation in MS patients persists six months after treatment termination and, together with resting state (RS) functional connectivity (FC), changes on neuropsychological performance at follow-up. Methods: Eighteen MS pa... ... hiện toàn bộ
Multiple Sclerosis Journal - Tập 20 Số 6 - Trang 686-694 - 2014
Outcomes assessment in multiple sclerosis clinical trials: a critical analysis The feasibility and precision of clinical trials for the treatment of MS must be improved Subsequent to the approval by the Food and Drug Administration of the United States of interferon beta-1b as a safe and effective, though not curative, treatment for relapsing-remitting MS, the testing of other agents in this disease has been undertaken or is anticipated. This report summarises the d... ... hiện toàn bộ
Multiple Sclerosis Journal - Tập 1 Số 1 - Trang 37-47 - 1995
Impact of 3 Tesla MRI on interobserver agreement in clinically isolated syndrome: A MAGNIMS multicentre studyBackground: Compared to 1.5 T, 3 T magnetic resonance imaging (MRI) increases signal-to-noise ratio leading to improved image quality. However, its clinical relevance in clinically isolated syndrome suggestive of multiple sclerosis remains uncertain. Objectives: The purpose of this study was t... ... hiện toàn bộ
Multiple Sclerosis Journal - Tập 25 Số 3 - Trang 352-360 - 2019
New insights into the burden and costs of multiple sclerosis in Europe: Results for ItalyIntroduction: In order to estimate the value of interventions in multiple sclerosis (MS) – where lifetime costs and outcomes cannot be observed – outcome data have to be combined with costs. This requires that cost data be regularly updated. Objectives and methods: This study is part of a cros... ... hiện toàn bộ
Multiple Sclerosis Journal - Tập 23 Số 2_suppl - Trang 104-116 - 2017
Promoting remyelination in multiple sclerosis: Current drugs and future prospects Myelin destruction due to inflammatory oligodendrocyte cell damage or death in conjunction with axonal degeneration are among the major histopathological hallmarks of multiple sclerosis (MS). The majority of available immunomodulatory medications for MS are approved for relapsing–remitting (RR) MS, for which they reduce relapse rate, MRI measures of inflammation, and the accumulation of d... ... hiện toàn bộ
Multiple Sclerosis Journal - Tập 21 Số 5 - Trang 541-549 - 2015
New insights into the burden and costs of multiple sclerosis in EuropeBackground: The current focus in multiple sclerosis (MS) is on early diagnosis and drug intervention, with a view to modifying disease progression. Consequently, healthcare costs have shifted from inpatient care and rehabilitation to outpatient care. Objectives: This European burden of illness... ... hiện toàn bộ
Multiple Sclerosis Journal - Tập 23 Số 8 - Trang 1123-1136 - 2017
Increasing incidence of multiple sclerosis in women in Northern Finland Background: The geographical distribution of multiple sclerosis (MS) means that prevalence rates increase with latitude north or south of the equator. Temporally, a tendency for increased incidences of MS has been observed over the past two decades. Objectives: Since epidemiological studies of MS in areas close to the Arctic Circle are rare, we evaluated the incidence an... ... hiện toàn bộ
Multiple Sclerosis Journal - Tập 17 Số 2 - Trang 133-138 - 2011
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