Patient perception of bodily functions in multiple sclerosis: gait and visual function are the most valuable

Multiple Sclerosis Journal - Tập 14 Số 7 - Trang 988-991 - 2008
Christoph Heesen1, Jiří Böhm1, Christine Reich2, Jürgen Kasper3, M Goebel1, Stefan M. Gold4
1Institute of Neuroimmunology and Clinical MS Research (INiMS), University Medical Center Hamburg-Eppendorf, Hamburg, Germany
2Competenzzentrum Versorgungsforschung in der Dermatologie (CVderm), University Medical Center Hamburg-Eppendorf, Hamburg, Germany
3Department of Health Sciences, University of Hamburg, Hamburg, Germany
4Multiple Sclerosis Program, Department of Neurology and Cousins Center for Psychoneuroimmunology, UCLA School of Medicine, Los Angeles, CA, USA

Tóm tắt

Multiple sclerosis is a heterogeneous disease with varying clinical picture. There have been substantial efforts to develop outcome measurements for therapeutic interventions but very few studies have addressed the value of bodily functions from the patient perspective. In a randomly selected cohort of early (<5 years, n = 84) and longer lasting disease courses (>15 years, n = 82) patients we asked for a weighting of 13 bodily functions and compared results with actual disability as measured by the United Kingdom Disability Scale. Lower limb function was given the highest priority in both patient groups followed by visual functioning and cognition especially in longer lasting MS. Actual disability did not correlate with the given priorities indicating that experienced deficits do not influence the subjective ratings of bodily functions. These results underline that ambulation-focused scales in MS represent a key dimension from the patient perspective. Visual functioning should be taken more into account.

Từ khóa


Tài liệu tham khảo

10.1093/brain/122.1.141

10.1007/s004150050204

10.1002/ana.410400321

10.1016/S1474-4422(05)70166-6

10.1136/bmj.314.7094.1580

10.1002/ana.410130302

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10.1177/135245859900500406

Heesen C, 2007, Neurol Rehab, 13, 24

10.1093/brain/122.5.871

10.1136/jnnp.74.4.439

10.1093/brain/awl223

Thông tin
Thông tin xuất bản

Multiple Sclerosis Journal

Tập 14 Số 7

988-991

Thông tin tác giả