A profile of multiple sclerosis: The New York State Multiple Sclerosis Consortium

Multiple Sclerosis Journal - Tập 5 Số 5 - Trang 369-376 - 1999
Lawrence Jacobs1, Karl Wende1, Carol M. Brownscheidle1, Brian Apatoff2, Patricia K. Coyle3, Andrew Goodman4, Malcolm Gottesman5, Carl V. Granger6, Steven J. Greenberg7, Joseph Herbert8, Lauren Krupp3, Neil Lava9, Cornelia Mihai10, Aaron Miller11, Allan Perel12, Charles R. Smith13, David H. Snyder14
1Department of Neurology, The Buffalo General Hospital, Buffalo, NY 14203, USA
2Department of Neurology and Neuroscience, Cornell Medical Center, New York, NY 10021, USA
3Department of Neurology, SUNY at Stony Brook University Hospital, Stony Brook, NY 11794, USA
4Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA
5Division of Neurology, Winthrop University Hospital, Mineola, NY 11501, USA
6Center for Functional Assessment Research, Rehabilitation Medicine Department, SUNY at Buffalo, Buffalo, NY 14214, USA
7Baird MS and Neuroimmunology Tissue Repository, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
8The Hospital for Joint Diseases Orthopaedic Institute, MS Care Center, New York, NY 10003, USA
9Department of Neurology, Albany Medical College, Albany, NY 12208 USA
10Department of Neurology, SUNY Health Science Center, Syracuse, NY 13210, USA
11Division of Neurology, Maimonides Medical Center, Brooklyn, NY 11219, USA
12MS Center, Staten Island University Hospital, Staten Island, NY 10306, USA
13MS Center, St. Agnes Hospital, White Plains, NY 10605, USA
14New York Hospital Medical Center of Queens, Flushing, NY 11355, USA

Tóm tắt

We have obtained a current profile of multiple sclerosis (MS) in New York State through a centralized patient registry and standardized data collection instrument associated with the New York State Multiple Sclerosis Consortium of 12 MS centers located throughout the state. Data from the first 3019 patients with clinically definite MS revealed a clear relationship between MS disease type, duration of disease, and severity of physical disability. Patients with relapsing disease had disease durations approximately half as long as those with progressive forms of the disease (means approximately 6 years versus 11 years). The majority of patients with relapsing disease had Expanded Disability Status Scale (EDSS) scores of 4.0 or less (self-sustained, fully ambulatory), whereas the majority of patients with progressive disease types had EDSS scores of 6.0 or greater (at least unilateral assist for walking). These findings emphasize the importance of early intervention in patients with relapsing disease to slow or prevent the accumulation of physical disability associated with progressive types of disease. Progressive disease was associated with lack of full-time employment and being disabled before the age of 60 years. Patients with relapsing disease were more likely to be employed and have private forms of insurance, whereas patients with progressive types of disease were more likely to have government-supported insurance to cover medical expenses.

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Multiple Sclerosis Journal

Tập 5 Số 5

369-376

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