Malaria Journal

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Costs analysis of the treatment of imported malaria
Malaria Journal - Tập 11 - Trang 1-5 - 2012
Viera Svihrova, Maria Szilagyiova, Elena Novakova, Jan Svihra, Henrieta Hudeckova
To document the status of imported malaria infections and estimate the costs of treating of patients hospitalized with the diagnosis of imported malaria in the Slovak Republic during 2003 to 2008. Calculating and comparing the direct and indirect costs of treatment of patients diagnosed with imported malaria (ICD-10: B50 - B54) who used and not used chemoprophylaxis. The target sample included 19 ...... hiện toàn bộ
Control of malaria in the Comoro Islands over the past century
Malaria Journal - Tập 16 - Trang 1-9 - 2017
Ismaël Chakir, Ali Ibrahim Said, Bacar Affane, Ronan Jambou
The Comoros are an archipelago located in the Indian Ocean between the eastern coasts of Africa and north of Madagascar. Malaria transmission appeared late in the 19th century due to the intensification of human migration. The story of malaria transmission for the past century is depicted to provide useful lessons for the future. Currently, malaria transmission occurs differently on each island; t...... hiện toàn bộ
PfMDR2 and PfMDR5 are dispensable for Plasmodium falciparum asexual parasite multiplication but change in vitro susceptibility to anti-malarial drugs
Malaria Journal - Tập 14 - Trang 1-7 - 2015
Maarten van der Velden, Sanna R Rijpma, Frans GM Russel, Robert W Sauerwein, Jan B Koenderink
Membrane-associated ATP binding cassette (ABC) transport proteins hydrolyze ATP in order to translocate a broad spectrum of substrates, from single ions to macromolecules across membranes. In humans, members from this transport family have been linked to drug resistance phenotypes, e.g., tumour resistance by enhanced export of chemotherapeutic agents from cancer cells due to gene amplifications or...... hiện toàn bộ
Monitoring Plasmodium vivax chloroquine sensitivity along China-Myanmar border of Yunnan Province, China during 2008–2013
Malaria Journal - Tập 13 Số 1 - 2014
Hui Liu, Henglin Yang, Lin-hua Tang, Xingliang Li, Fang Huang, Jiazhi Wang, Chunfu Li, Wang HengYe, Rong Nie, Xiang-rui Guo, Yexin Lin, Mei Li, Jianwei Xu
Artesunate-amodiaquine efficacy in Congolese children with acute uncomplicated falciparum malaria in Brazzaville
Malaria Journal - Tập 12 - Trang 1-8 - 2013
Mathieu Ndounga, Pembe Issamou Mayengue, Prisca Nadine Casimiro, Dieudonné Loumouamou, Leonardo K Basco, Francine Ntoumi, Philippe Brasseur
Congo-Brazzaville adopted artemisinin-based combination therapy (ACT) in 2006. Artesunate-amodiaquine (AS + AQ) and artemether-lumefantrine are the first-line and second-line anti-malarial drugs to treat uncomplicated Plasmodium falciparum malaria, respectively. The baseline efficacy of AS + AQ was evaluated from February to August 2005 in patients living in Brazzaville, the capital city of the Re...... hiện toàn bộ
Geometric least squares means ratios for the analysis of Plasmodium falciparum in vitro susceptibility to antimalarial drugs
Malaria Journal - Tập 6 - Trang 1-11 - 2007
Michel Vaillant, Piero Olliaro
The susceptibility of microbes such as Plasmodium falciparum to drugs is measured in vitro as the concentration of the drug achieving 50% of maximum effect (IC50); values from a population are summarized as geometric means. For antimalarial drugs, as well as for antibiotics, assessing changes in microbe susceptibility over time under drug pressure would help inform treatment policy decisions, but ...... hiện toàn bộ
Validation of an enzyme-linked immunosorbent assay for the quantification of human IgG directed against the repeat region of the circumsporozoite protein of the parasite Plasmodium falciparum
Malaria Journal - Tập 11 - Trang 1-15 - 2012
Frederic Clement, Vincent Dewar, Eva Van Braeckel, Isabelle Desombere, Marianne Dewerchin, Christine Swysen, Marie-Ange Demoitié, Erik Jongert, Joe Cohen, Geert Leroux-Roels, Pierre Cambron
Several pre-erythrocytic malaria vaccines based on the circumsporozoite protein (CSP) antigen of Plasmodium falciparum are in clinical development. Vaccine immunogenicity is commonly evaluated by the determination of anti-CSP antibody levels using IgG-based assays, but no standard assay is available to allow comparison of the different vaccines. The validation of an anti-CSP repeat region enzyme-l...... hiện toàn bộ
Các yếu tố xác định việc xét nghiệm sốt rét tại các cơ sở y tế: trường hợp Uganda Dịch bởi AI
Malaria Journal - Tập 20 Số 1 - 2021
Ruth Kigozi, JohnBaptist Bwanika, Emily Goodwin, P. E. Thomas, Patrick Bukoma, Persis Nabyonga, Fred Isabirye, Paul Oboth, Carol Kyozira, Mame Niang, Kassahun Belay, Gloria Sebikaari, James Tibenderana, Sam Siduda Gudoi
Tóm tắt Hoàn cảnh Tổ chức Y tế Thế giới (WHO) khuyến nghị việc chẩn đoán sốt rét kịp thời bằng kính hiển vi hoặc các xét nghiệm nhanh chẩn đoán sốt rét (RDT) và điều trị bằng thuốc chống sốt rét hiệu quả, như những biện pháp can thiệp chính nhằm kiểm soát bệnh sốt rét. Tuy nhiên, ở khu vực hạ Sahara...... hiện toàn bộ
The Duffy binding protein (PkDBPαII) of Plasmodium knowlesi from Peninsular Malaysia and Malaysian Borneo show different binding activity level to human erythrocytes
Malaria Journal - Tập 16 Số 1 - Trang 1-8 - 2017
Lim, Khai Lone, Amir, Amirah, Lau, Yee Ling, Fong, Mun Yik
The zoonotic Plasmodium knowlesi is a major cause of human malaria in Malaysia. This parasite uses the Duffy binding protein (PkDBPαII) to interact with the Duffy antigen receptor for chemokines (DARC) receptor on human and macaque erythrocytes to initiate invasion. Previous studies on P. knowlesi have reported distinct Peninsular Malaysia and Malaysian Borneo PkDBPαII haplotypes. In the present s...... hiện toàn bộ
Climate forcing and desert malaria: the effect of irrigation
Malaria Journal - - 2011
Andrés Baeza, Menno J. Bouma, Andy Dobson, R. C. Dhiman, H. C. Srivastava, Mercedes Pascual
Abstract Background Rainfall variability and associated remote sensing indices for vegetation are central to the development of early warning systems for epidemic malaria in arid regions. The considerable change in land-use practices resulting from increasing irrigation in recent decades raises i...... hiện toàn bộ
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