A large proportion of asymptomatic Plasmodium infections with low and sub-microscopic parasite densities in the low transmission setting of Temotu Province, Solomon Islands: challenges for malaria diagnostics in an elimination setting Tập 9 Số 1 - 2010
Ivor Harris, Wesley W Sharrock, Lisa Bain, Karen-Ann Gray, Albino Bobogare, Leonard Boaz, Ken Lilley, Darren Krause, Andrew Vallely, Marie-Louise Johnson, Michelle L. Gatton, G. Dennis Shanks, Qin Cheng
Abstract
Background
Many countries are scaling up malaria interventions towards elimination. This transition changes demands on malaria diagnostics from diagnosing ill patients to detecting parasites in all carriers including asymptomatic infections and infections with low parasite densities. Det...... hiện toàn bộ Designing the next generation of medicines for malaria control and eradication - 2013
Jeremy N. Burrows, Rob Hooft van Huijsduijnen, Jörg J. Möhrle, Claude Oeuvray, Timothy N.C. Wells
Abstract
In the fight against malaria new medicines are an essential weapon. For the parts of the world where the current gold standard artemisinin combination therapies are active, significant improvements can still be made: for example combination medicines which allow for single dose regimens, cheaper, safer and more effective medicines, or improved st...... hiện toàn bộ A general SNP-based molecular barcode for Plasmodium falciparum identification and tracking Tập 7 Số 1 - 2008
Rachel F. Daniels, Sarah K. Volkman, Danny A. Milner, Nira Mahesh, Daniel E. Neafsey, Daniel J. Park, David Rosen, Elaine Angelino, Pardis C. Sabeti, Dyann F. Wirth, Roger C. Wiegand
Abstract
Background
Single nucleotide polymorphism (SNP) genotyping provides the means to develop a practical, rapid, inexpensive assay that will uniquely identify any Plasmodium falciparum parasite using a small amount of DNA. Such an assay could be used to distinguish...... hiện toàn bộ Concentration and purification by magnetic separation of the erythrocytic stages of all human Plasmodium species Tập 7 Số 1 - 2008
Clotilde Ribaut, Antoine Berry, Séverine Chevalley, Karine Reybier, Isabelle Morlais, Daniel Parzy, Françoise Nepveu, Françoise Benoit‐Vical, Alexis Valentin
Abstract
Background
Parasite concentration methods facilitate molecular, biochemical and immunological research on the erythrocytic stages of Plasmodium. In this paper, an adaptation of magnetic MACS® columns for the purification of human ... hiện toàn bộ Clustered local transmission and asymptomatic Plasmodium falciparum and Plasmodium vivax malaria infections in a recently emerged, hypoendemic Peruvian Amazon community Tập 4 Số 1 - 2005
OraLee H. Branch, W. Martin Casapia, Dionicia Gamboa, Jean N. Hernandez, Freddy Alava, Norma Roncal, Eugenia Alvarez, Enrique J. Martínez Pérez, Eduardo Gotuzzo
Abstract
Background
There is a low incidence of malaria in Iquitos, Peru, suburbs detected by passive case-detection. This low incidence might be attributable to infections clustered in some households/regions and/or undetected asymptomatic infections.
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