Malaria Journal
SCIE-ISI SCOPUS (2002-2025)
1475-2875
Cơ quản chủ quản: BioMed Central Ltd. , BMC
Lĩnh vực:
ParasitologyInfectious Diseases
Phân tích ảnh hưởng
Các bài báo tiêu biểu
A large proportion of asymptomatic Plasmodium infections with low and sub-microscopic parasite densities in the low transmission setting of Temotu Province, Solomon Islands: challenges for malaria diagnostics in an elimination setting
Tập 9 Số 1 - 2010
Abstract Background Many countries are scaling up malaria interventions towards
elimination. This transition changes demands on malaria diagnostics from
diagnosing ill patients to detecting parasites in all carriers including
asymptomatic infections and infections with low parasite densities. Detection
methods suitable to local malaria epidemiology must be selected prior to
transitioning a malaria...
Designing the next generation of medicines for malaria control and eradication
- 2013
Abstract In the fight against malaria new medicines are an essential weapon. For
the parts of the world where the current gold standard artemisinin combination
therapies are active, significant improvements can still be made: for example
combination medicines which allow for single dose regimens, cheaper, safer and
more effective medicines, or improved stability under field conditions. For
those p...
A general SNP-based molecular barcode for Plasmodium falciparum identification and tracking
Tập 7 Số 1 - 2008
Abstract Background Single nucleotide polymorphism (SNP) genotyping provides the
means to develop a practical, rapid, inexpensive assay that will uniquely
identify any Plasmodium falciparum parasite using a small amount of DNA. Such an
assay could be used to distinguish recrudescence from re-infection in drug
trials, to monitor the frequency and distribution of specific parasites in a
patient popu...
Concentration and purification by magnetic separation of the erythrocytic stages of all human Plasmodium species
Tập 7 Số 1 - 2008
Abstract Background Parasite concentration methods facilitate molecular,
biochemical and immunological research on the erythrocytic stages of Plasmodium.
In this paper, an adaptation of magnetic MACS® columns for the purification of
human Plasmodium species is presented. This method was useful for the
concentration/purification of either schizonts or gametocytes. Results and
conclusions The magnet...
False-negative malaria rapid diagnostic tests in Rwanda: impact of Plasmodium falciparum isolates lacking hrp2 and declining malaria transmission
Tập 16 - Trang 1-11 - 2017
Rapid diagnostic tests (RDTs) for histidine rich protein 2 (HRP2) are often used
to determine whether persons with fever should be treated with anti-malarials.
However, Plasmodium falciparum parasites with a deletion of the hrp2 gene yield
false-negative RDTs and there are concerns the sensitivity of HRP2-based RDTs
may fall when the intensity of transmission decreases. This observational study
en...