Lupus

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Clinical significance of serum and urine prolactin levels in lupus glomerulonephritis
Lupus - Tập 7 Số 6 - Trang 387-391 - 1998
J M Miranda, Rodrigo Prieto, Ramón Paniagua, Gloria García, Dante Amato, Leonor Barile, Luis J. Jara
Prolactin (PRL) has been involved in the pathogenesis of systemic lupus erythematosus (SLE) and hyperprolactinemia has been connected with systemic activity. However, the clinical significance of PRL has not been investigated in lupus glomerulonephritis (GN). Methods: We studied SLE patients (ACR criteria) with biopsy-proven renal disease. Renal histology was classified according to World...... hiện toàn bộ
Hematopoietic stem cell transplant for systemic lupus erythematosus: Interferon regulatory factor 7 activation correlates with the IFN signature and recurrent disease
Lupus - Tập 20 Số 9 - Trang 975-980 - 2011
SE Sweeney
The expression and activation of regulatory factors (IRF) and rinterferon (IFN) response genes were evaluated in a patient treated with autologous hematopoietic stem cell transplant (HSCT) for refractory systemic lupus erythematosus (SLE). In SLE patients, genetic variants of IRF5 and IRF7 have been associated with increased serum IFNα levels, suggesting a pathogenic role in the type I IF...... hiện toàn bộ
Extrahepatic manifestations in chronic hepatitis C virus carriers
Lupus - Tập 24 Số 4-5 - Trang 469-482 - 2015
Éric Rosenthal, P. Cacoub
Patients with chronic hepatitis C virus (HCV) infection frequently present with extrahepatic manifestations covering a large spectrum, involving different organ systems leading to the concept of systemic HCV infection. These manifestations include autoimmune phenomena and frank autoimmune and/or rheumatic diseases and may dominate the course of chronic HCV infection. Chronic HCV infection...... hiện toàn bộ
Annular erythema in primary Sjögren’s syndrome: description of 43 non-Asian cases
Lupus - Tập 23 Số 2 - Trang 166-175 - 2014
Pilar Brito‐Zerón, Soledad Retamozo, Miriam Akasbi, Myriam Gandía, M. Pérez-de-Lis, M.J. Soto Cárdenas, Cándido Díaz‐Lagares, Belchin Kostov, Albert Selva-O’Callaghan, Xavier Bosch, R. Pérez-Álvarez, Antoni Xaubet, Manuel Ramos‐Casals
Objective The objective of this paper is to evaluate the prevalence and characterize the main epidemiological, clinical and immunological features of annular erythema (AE) in non-Asian patients with primary Sjögren’s syndrome (SS). Methods We carried out a retrospective study searching for AE ...... hiện toàn bộ
Primary antithrombotic prevention in carriers of antiphospholipid antibodies without systemic autoimmune disorders
Lupus - Tập 21 Số 7 - Trang 747-750 - 2012
Guido Finazzi
Primary antithrombotic prevention with aspirin is not indicated in asymptomatic patients with confirmed antiphospholipid (aPL) positivity without systemic autoimmune disorders because: a) the estimated prevalence of thrombosis in unselected cases is about 1% patient-years (range 0–2.8); b) this level of thrombotic risk is equivalent to that of major bleeding associated with the use of asp...... hiện toàn bộ
Factors associated with chloroquine-induced retinopathy in rheumatic diseases
Lupus - Tập 13 Số 2 - Trang 119-124 - 2004
Rodolfo Araiza-Casillas, Maria Cardenas, Y Morales, Mario H. Cardiel
Antimalarials are very useful drugs in the treatment of various rheumatic diseases. One of their main side effects is ocular toxicity, specifically retinopathy. Our objective was to identify risk factors associated with chloroquine retinopathy. A single, trained evaluator reviewed patient records with rheumatic diseases. They were taking chloroquine and identified by the ophthalmologydepa...... hiện toàn bộ
Myocardial tissue characterization in systemic lupus erythematosus: value of a comprehensive cardiovascular magnetic resonance approach
Lupus - Tập 17 Số 6 - Trang 561-567 - 2008
Hassan Abdel‐Aty, N Siegle, Alexander Natusch, Erika Gromnica‐Ihle, Ralf Waßmuth, Rainer Dietz, Jeanette Schulz‐Menger
Systemic lupus erythematosus (SLE) is a multi-organ inflammatory disorder mainly affecting women and is associated with high cardiovascular morbidity and mortality. We tested the utility of a comprehensive cardiovascular magnetic resonance approach to assess myocardial involvement and to determine its relation to disease activity in SLE patients. We studied 20 SLE patients (19 females, 35...... hiện toàn bộ
Autoimmune myocarditis and dilated cardiomyopathy: focus on cardiac autoantibodies
Lupus - Tập 14 Số 9 - Trang 652-655 - 2005
Alida L.P. Caforio, Luciano Daliento, Annalisa Angelini, Stefania Bottaro, Annalisa Vinci, Greta Dequal, F. Tona, Sabino Iliceto, Gaetano Thiene, William J. McKenna
Criteria of organ-specific autoimmunity are fulfilled in a subset of patients with myocarditis/dilated cardiomyopathy (DCM). In particular, circulating heart-reactive autoantibodies are found in patients and symptom-free relatives. These autoantibodies are directed against multiple antigens, some of which are expressed in the heart (organ-specific), others in heart and some skeletal muscl...... hiện toàn bộ
Cardiac involvement in small and medium-sized vessel vasculitides
Lupus - Tập 14 Số 9 - Trang 718-722 - 2005
Christian Lavigne, Loı̈c Guillevin
The heart can be involved in vasculitides but the frequency of its involvement and the manifestations vary according to the vasculitis. Cardiovascular manifestations include cardiomyopathy (specific or resulting from myocardial infarctions), coronary arteritis (with risk of aneurysms, stenoses and thrombosis formation or rupture), pericarditis, valvulitis, conduction-tissue involvement (w...... hiện toàn bộ
Cardiac magnetic resonance imaging abnormalities in systemic lupus erythematosus: a preliminary report
Lupus - Tập 14 Số 2 - Trang 137-144 - 2005
Jasvinder A. Singh, Pamela K. Woodard, Víctor G. Dávila‐Román, Alan D. Waggoner, Fernando R. Gutiérrez, Jie Zheng, Seth A. Eisen
The purpose of this prospective, pilot study was to determine whether differences in myocardial T2 relaxivity can be identified among active systemic lupus erythematosus (SLE) patients with clinically suspected SLE myocarditis, other active SLE patients, inactive SLE patients and age and gender matched controls. Eleven consecutive female patients (six with active SLE and five with inactiv...... hiện toàn bộ
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