Journal of the Association for Research in Otolaryngology

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Effects of Stimulation Rate, Mode and Level on Modulation Detection by Cochlear Implant Users
Journal of the Association for Research in Otolaryngology - Tập 6 - Trang 269-279 - 2005
John J. Galvin, Qian-Jie Fu
In cochlear implant (CI) patients, temporal processing is often poorest at low listening levels, making perception difficult for low-amplitude temporal cues that are important for consonant recognition and/or speech perception in noise. It remains unclear how speech processor parameters such as stimulation rate and stimulation mode may affect temporal processing, especially at low listening levels... hiện toàn bộ
Effects of Hearing Preservation on Psychophysical Responses to Cochlear Implant Stimulation
Journal of the Association for Research in Otolaryngology - Tập 11 - Trang 245-265 - 2009
Stephen Y. Kang, Deborah J. Colesa, Donald L. Swiderski, Gina L. Su, Yehoash Raphael, Bryan E. Pfingst
Previous studies have shown that residual acoustic hearing supplements cochlear implant function to improve speech recognition in noise as well as perception of music. The current study had two primary objectives. First, we sought to determine how cochlear implantation and electrical stimulation over a time period of 14 to 21 months influence cochlear structures such as hair cells and spiral gangl... hiện toàn bộ
Polygenic Risk Score-Based Association Analysis of Speech-in-Noise and Hearing Threshold Measures in Healthy Young Adults with Self-reported Normal Hearing
Journal of the Association for Research in Otolaryngology - Tập 24 - Trang 513-525 - 2023
Ishan Sunilkumar Bhatt, Sai Kumar Ramadugu, Shawn Goodman, Srividya Grama Bhagavan, Valerie Ingalls, Raquel Dias, Ali Torkamani
Speech-in-noise (SIN) traits exhibit high inter-subject variability, even for healthy young adults reporting normal hearing. Emerging evidence suggests that genetic variability could influence inter-subject variability in SIN traits. Genome-wide association studies (GWAS) have uncovered the polygenic architecture of various adult-onset complex human conditions. Polygenic risk scores (PRS) summariz... hiện toàn bộ
Knock-in Mouse Model for Resistance to Thyroid Hormone (RTH): An RTH Mutation in the Thyroid Hormone Receptor Beta Gene Disrupts Cochlear Morphogenesis
Journal of the Association for Research in Otolaryngology - - 2002
Andrew J. Griffith, Yvonne M. Szymko, Masahiro Kaneshige, Rafael E. Quiñónez, Kumiko Kaneshige, Kasey A. Heintz, Mary Ann Mastroianni, Matthew W. Kelley, Sheue-yann Cheng
Thyroid hormone and the beta isoform of its receptor, Trb, are essential for normal development of the mammalian auditory system. We have analyzed auditory system function and structure in a mouse strain with a targeted Thrb mutation, ThrbPV, which leads to the loss of binding of thyroid hormone (T3) to the Trb protein. Heterozygosity for the orthologous human THRBPV mutation and other similar mut... hiện toàn bộ
Correction to: Aminoglycoside Damage and Hair Cell Regeneration in the Chicken Utricle
Journal of the Association for Research in Otolaryngology - Tập 19 - Trang 31-31 - 2018
Mirko Scheibinger, Daniel C. Ellwanger, C. Eduardo Corrales, Jennifer S. Stone, Stefan Heller
This article was updated to correct a formatting error in Table 1.
Voice Discrimination by Adults with Cochlear Implants: the Benefits of Early Implantation for Vocal-Tract Length Perception
Journal of the Association for Research in Otolaryngology - - 2018
Yael Zaltz, Raymond L. Goldsworthy, Liat Kishon‐Rabin, Laurie S. Eisenberg
Disruption of Lateral Olivocochlear Neurons via a Dopaminergic Neurotoxin Depresses Sound-Evoked Auditory Nerve Activity
Journal of the Association for Research in Otolaryngology - Tập 6 - Trang 48-62 - 2005
Colleen G. Le Prell, KÄrin Halsey, Larry F. Hughes, David F. Dolan, Sanford C. Bledsoe
We applied the dopaminergic (DA) neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to the guinea pig cochlear perilymph. Immunolabeling of lateral olivocochlear (LOC) neurons using antibodies against synaptophysin was reduced after the MPTP treatment. In contrast, labeling of the medial olivocochlear innervation remained intact. As after brainstem lesions of the lateral superior olive... hiện toàn bộ
Experimental Evidence for a Cochlear Source of the Precedence Effect
Journal of the Association for Research in Otolaryngology - Tập 14 Số 5 - Trang 767-779 - 2013
Bianchi, Federica, Verhulst, Sarah, Dau, Torsten
The precedence effect (PE) refers to the dominance of directional information carried by a direct sound (lead) over the spatial information contained in its multiple reflections (lags) in sound localization. Although the processes underlying the PE have been largely investigated, the extent to which peripheral versus central auditory processes contribute to this perceptual phenomenon has remained ... hiện toàn bộ
Finite-Element Modelling Based on Optical Coherence Tomography and Corresponding X-ray MicroCT Data for Three Human Middle Ears
Journal of the Association for Research in Otolaryngology - Tập 24 Số 3 - Trang 339-363
Marzieh Golabbakhsh, Xuan Wang, Dan MacDougall, Joshua Farrell, Thomas Landry, W. Robert J. Funnell, Robert Adamson
Perceptual Weighting of Binaural Lateralization Cues across Frequency Bands
Journal of the Association for Research in Otolaryngology - Tập 21 - Trang 485-496 - 2020
Axel Ahrens, Suyash Narendra Joshi, Bastian Epp
The auditory system uses interaural time and level differences (ITD and ILD) as cues to localize and lateralize sounds. The availability of ITDs and ILDs in the auditory system is limited by neural phase-locking and by the head size, respectively. Although the frequency-specific limitations are well known, the relative contribution of ITDs and ILDs in individual frequency bands in broadband stimul... hiện toàn bộ
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