Journal of integrative bioinformatics

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Prediction of thioredoxin and glutaredoxin target proteins by identifying reversibly oxidized cysteinyl residues
Journal of integrative bioinformatics - Tập 7 Số 3 - Trang 208-218 - 2010
Hang-mao Lee, Karl‐Josef Dietz, Ralf Hofestädt
Summary A significant part of cellular proteins undergo reversible thiol-dependent redox transitions which often control or switch protein functions. Thioredoxins and glutaredoxins constitute two key players in this redox regulatory protein network. Both interact with various categories of proteins containing reversibly oxidized cysteinyl residues. The identificati...... hiện toàn bộ
Current Progress of High-Throughput MicroRNA Differential Expression Analysis and Random Forest Gene Selection for Model and Non-Model Systems: an R Implementation
Journal of integrative bioinformatics - Tập 13 Số 5 - 2016
Jing Zhang, Hanane Hadj‐Moussa, Kenneth B. Storey
SummaryMicroRNAs are short non-coding RNA transcripts that act as master cellular regulators with roles in orchestrating virtually all biological functions. The recent affordability and widespread use of high-throughput microRNA profiling technologies has grown along with the advancement of bioinformatics tools available for analysis of the mounting data flow. Whil...... hiện toàn bộ
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