Journal of extracellular vesicles
SCOPUS (SonsInc.)SCIE-ISI
2001-3078
Cơ quản chủ quản: John Wiley & Sons Inc. , WILEY
Lĩnh vực:
Cell BiologyHistology
Các bài báo tiêu biểu
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelinesABSTRACT The last decade has seen a sharp increase in the number of scientific publications describing physiological and pathological functions of extracellular vesicles (EVs), a collective term covering various subtypes of cell‐released, membranous structures, called exosomes, microvesicles, microparticles, ectosomes, oncosomes, apoptotic bodies, and many other nam... ... hiện toàn bộ
Tập 7 Số 1 - 2018
Optimized exosome isolation protocol for cell culture supernatant and human plasmaExtracellular vesicles represent a rich source of novel biomarkers in the diagnosis and prognosis of disease. However, there is currently limited information elucidating the most efficient methods for obtaining high yields of pure exosomes, a subset of extracellular vesicles, from cell culture supernatant and complex biological fluids such as plasma. To this end, we comprehensively charact... ... hiện toàn bộ
Tập 4 Số 1 - 2015
Neutral sphingomyelinases control extracellular vesicles budding from the plasma membraneABSTRACT Extracellular vesicles (EVs) are membrane particles secreted from cells into all body fluids. Several EV populations exist differing in size and cellular origin. Using differential centrifugation EVs pelleting at 14,000 g (“microvesicles” (MV)) and 100,000 g (“exosomes”) are distinguishable by protein markers. Neutral sphingomyelinase (nSMase) inhibition ha... ... hiện toàn bộ
Tập 6 Số 1 - 2017
Size and concentration analyses of extracellular vesicles by nanoparticle tracking analysis: a variation studyABSTRACT Current methods for characterisation of extracellular vesicles (EVs) need further standardisation in order to obtain an acceptable level of data comparability. Size and concentration of EVs can be determined by nanoparticle tracking analysis (NTA). However, both the heterogeneity of EVs and the choice of instrument settings may cause an appreciable analytic... ... hiện toàn bộ
Tập 6 Số 1 - 2017
Effect of storage on physical and functional properties of extracellular vesicles derived from neutrophilic granulocytesAim To carry out a systematic study on the effect of different storage conditions on the number as well as the physical and functional properties of antibacterial extracellular vesicles (EVs) derived from human neutrophilic granulocytes. Methods Production of EVs with antibacterial properties was...
Tập 3 Số 1 - 2014
Evaluation of circulating small extracellular vesicles derived miRNAs as biomarkers of early colon cancer: a comparison with plasma total miRNAsABSTRACT Early diagnosis of colon cancer (CC) is clinically important, as it can significantly improve patients' survival rate and quality of life. Although the potential role for small extracellular vesicles (sEVs) in early detection of many diseases has been repeatedly mentioned, systematic screening of plasma sEVs derived early CC specific biomarkers has not yet ... ... hiện toàn bộ
Tập 8 Số 1 - 2019
Comparative analysis of EV isolation procedures for miRNAs detection in serum samplesExtracellular vesicles (EVs) are emerging as potent non‐invasive biomarkers. However, current methodologies are time consuming and difficult to translate to clinical practice. To analyse EV‐encapsulated circulating miRNA, we searched for a quick, easy and economic method to enrich frozen human serum samples for EV. We compared the efficiency of several protocols and commercial kits to isol... ... hiện toàn bộ
Tập 5 Số 1 - 2016
MiR155‐5p in adventitial fibroblasts‐derived extracellular vesicles inhibits vascular smooth muscle cell proliferation via suppressing angiotensin‐converting enzyme expressionABSTRACT Proliferation of vascular smooth muscle cells (VSMCs) plays crucial roles in vascular remodelling and stiffening in hypertension. Vascular adventitial fibroblasts are a key regulator of vascular wall function and structure. This study is designed to investigate the roles of adventitial fibroblasts‐derived extracellular vesicles (EVs) in VSMC proliferation a... ... hiện toàn bộ
Tập 9 Số 1 - 2020
An experimental strategy unveiling exosomal microRNAs 486‐5p, 181a‐5p and 30d‐5p from hypoxic tumour cells as circulating indicators of high‐risk rectal cancerABSTRACT Tumour hypoxia contributes to poor treatment outcome in locally advanced rectal cancer (LARC) and circulating extracellular vesicles (EVs) as potential biomarkers of tumour hypoxia and adverse prognosis have not been fully explored. We examined EV miRNAs from hypoxic colorectal cancer cell lines as template for relevant miRNAs in LARC patients participating... ... hiện toàn bộ
Tập 8 Số 1 - 2019
Prostate cancer extracellular vesicles mediate intercellular communication with bone marrow cells and promote metastasis in a cholesterol‐dependent mannerAbstract Primary tumours can establish long‐range communication with distant
organs to transform them into fertile soil for circulating tumour cells to
implant and proliferate, a process called pre‐metastatic niche (PMN) formation. Tumour‐derived extracellular vesicles (EV) are potent mediators of PMN formation due to their diverse complement of pro‐malignant mole... ... hiện toàn bộ
Tập 10 Số 2 - 2020