Đại dịch học về viêm gan B mãn tính âm tính với HBeAg và các biến thể precore và core promoter trên toàn thế giới Dịch bởi AI Tập 9 Số 1 - Trang 52-61 - 2002
M. Jonsson Funk, D Rosenberg, Anna S. Lok
Viêm gan B là một căn bệnh nghiêm trọng đang lưu hành ở nhiều vùng trên thế
giới. Một tỷ lệ đáng kể bệnh nhân viêm gan B mãn tính (CHB) bị nhiễm một dạng
biến thể của virus viêm gan B (HBV) làm giảm hoặc làm mất sự sản xuất kháng
nguyên e viêm gan B (HBeAg). Mục đích của bài tổng quan tài liệu này là mô tả
dịch tễ học của CHB âm tính với HBeAg (e-CHB) trên toàn cầu. Một cuộc tìm kiếm
tài liệu đã đ... hiện toàn bộ
#Viêm gan B #mãn tính #âm tính với HBeAg #biến thể precore #biến thể core promoter #dịch tễ học.
Meta‐analysis of observational studies: hepatitis C and survival after renal transplant Tập 21 Số 5 - Trang 314-324 - 2014
F. Fabrizi, Paul Martin, V. K. Dixit, Piergiorgio Messa
SummaryRecent evidence has shown that anti‐HCV‐positive serologic status is
significantly linked to lower patient and graft survival after renal transplant,
but conflicting results have been given on this point. The aim of this study was
to conduct a systematic review of the published medical literature concerning
the impact of HCV infection on all‐cause mortality and graft loss after RT. The
rela... hiện toàn bộ
A placebo‐controlled phase I/II study of adefovir dipivoxil in patients with chronic hepatitis B virus infection Tập 6 Số 5 - Trang 387-395 - 1999
Richard Gilson, Kapil Chopra, A Newell, I M Murray-Lyon, Mark Nelson, S J Rice, Richard S. Tedder, John J. Toole, H S Jaffe, Ian Weller
Adefovir dipivoxil (bis‐POM PMEA) is an adenine nucleotide analogue with
activity against retroviruses and herpesviruses, and in vitro activity against
hepatitis B virus (HBV). This study was conducted to evaluate its safety and
antiviral activity in patients with chronic HBV infection. Twenty patients (13
co‐infected with human immunodeficiency virus, HIV) were randomized in a phase
I/II, double‐... hiện toàn bộ
Increased Th17 cells contribute to disease progression in patients with HBV‐associated liver cirrhosis Tập 19 Số 6 - Trang 396-403 - 2012
Hongqi Sun, Ji‐yuan Zhang, Huixia Zhang, Zhengsheng Zou, F. S. Wang, Jinlin Jia
Summary. T helper (Th) 17 cells have been demonstrated to participate in the
pathogenesis of HBV‐associated liver damage. However, little is known regarding
the immunopathogenic role of liver fibrosis in patients with HBV‐associated
liver cirrhosis. The aims of this study were to evaluate whether Th17 cells are
related to disease progression in patients and to explore the possible
mechanisms. The... hiện toàn bộ
Incidence of Hepatitis A in Argentina after vaccination Tập 15 Số s2 - Trang 47-50 - 2008
M Vacchino
Summary. In Argentina, the annual incidence rate of reported hepatitis A
disease ranged from 70.5 to 173.8 per 100 000 during 1995–2004. A single dose
universal hepatitis A immunization program aimed at children aged 12 months was
started in June 2005. The aim was to observe the impact of universal vaccination
against hepatitis A in Argentina. A longitudinal analysis of hepatitis A rates
reported... hiện toàn bộ
Hepatitis C virus and the brain Tập 19 Số 5 - Trang 301-306 - 2012
Nicola F. Fletcher, Jane A. McKeating
Summary. Hepatitis C virus (HCV) is an enveloped, positive‐strand RNA virus of
the family Flaviviridae that primarily infects hepatocytes, causing acute and
chronic liver disease. HCV is also associated with a variety of extrahepatic
symptoms including central nervous system (CNS) abnormalities, cognitive
dysfunction, fatigue and depression. These symptoms do not correlate with the
severity of li... hiện toàn bộ
Biochemical and structural analysis of the NS5B RNA‐dependent RNA polymerase of the hepatitis C virus Tập 7 Số 3 - Trang 167-174 - 2000
Volker Lohmann, G Roos, Körner, André Koch, Ralf Bartenschlager
Hepatitis C virus (HCV), the major causative agent of chronic and sporadic
non‐A, non‐B hepatitis worldwide, is a distinct member of the Flaviviridae virus
family. These viruses have in common a plus‐strand RNA genome that is replicated
in the cytoplasm of the infected cell via minus‐strand RNA intermediates. Owing
to the lack of reliable cell culture systems and convenient animal models for
HCV, ... hiện toàn bộ
Hepatitis C virus infection: a risk factor for Parkinson's disease Tập 22 Số 10 - Trang 784-791 - 2015
Wan‐Jung Wu, Kai‐Hsiang Kang, S. L.‐S. Chen, Shih-Jung Chiu, Amy Ming‐Fang Yen, J. C.‐Y. Fann, Chien‐Wei Su, Huiyu Liu, Chuan–Mo Lee, Wen‐Mei Fu, Chien-Jen Chen, Horng‐Huei Liou
SummaryRecent studies found that hepatitis C virus (HCV) may invade the central
nervous system, and both HCV and Parkinson's disease (PD) have in common the
overexpression of inflammatory biomarkers. We analysed data from a
community‐based integrated screening programme based on a total of 62 276
subjects. We used logistic regression models to investigate association between
HCV infection and PD. ... hiện toàn bộ
Cytokine profile of peripheral blood mononuclear cells from patients with different outcomes of hepatitis C virus infection Tập 12 Số 5 - Trang 525-530 - 2005
Annagiulia Gramenzi, Pietro Andreoné, E. Loggi, Francesco Giuseppe Foschi, C. Cursaro, Marzia Margotti, Maurizio Biselli, M. Bernardi
Summary. The relationship between the balance of helper T‐cell type 1 (Th1) or
type 2 (Th2) cytokines and the clinical course of hepatitis C virus (HCV)
infection is unclear. We evaluated Th1 [interleukin (IL)‐2, interferon‐gamma
(IFN‐γ)] and Th2 cytokine (IL‐4, IL‐10) and 2,5‐oligoadenylate synthetase (OAS,
an IFN‐induced antiviral protein) production by peripheral blood mononuclear
cells from 1... hiện toàn bộ