Journal of Viral Hepatitis

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Prevention of allograft HCV recurrence with peri‐transplant human monoclonal antibody MBL‐HCV1 combined with a single oral direct‐acting antiviral: A proof‐of‐concept study
Journal of Viral Hepatitis - Tập 24 Số 3 - Trang 197-206 - 2017
Heidi L. Smith, Raymond T. Chung, Parvez Mantry, William C. Chapman, Michael P. Curry, Thomas D. Schiano, Elisabeth N. Boucher, Peter Cheslock, Y. Wang, Deborah C. Molrine
SummaryPatients with active hepatitis C virus (HCV) infection at transplantation experience rapid allograft infection, increased risk of graft failure and accelerated fibrosis. MBL‐HCV... hiện toàn bộ
Hepatitis C virus infection: a risk factor for Parkinson's disease
Journal of Viral Hepatitis - Tập 22 Số 10 - Trang 784-791 - 2015
Wan‐Jung Wu, Kai‐Hsiang Kang, S. L.‐S. Chen, Shih-Jung Chiu, Amy Ming‐Fang Yen, J. C.‐Y. Fann, Chien‐Wei Su, Huiyu Liu, Chuan–Mo Lee, Wen‐Mei Fu, Chien-Jen Chen, Horng‐Huei Liou
SummaryRecent studies found that hepatitis C virus (HCV) may invade the central nervous system, and both HCV and Parkinson's disease (PD) have in common the overexpression of inflam...... hiện toàn bộ
Association between viral hepatitis infection and Parkinson's disease: A population‐based prospective study
Journal of Viral Hepatitis - Tập 27 Số 11 - Trang 1171-1178 - 2020
Hwa Young Choi, Ha T, Kyung‐Ah Kim, Hyunsoon Cho, Moran Ki
AbstractThe association between hepatitis virus infection and Parkinson's disease remains controversial. To determine whether hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are associated with an increased risk of Parkinson's disease in Korean aged ≥40 years, we completed a population‐based prospective study including patients without infections and...... hiện toàn bộ
Modulation of the anti‐inflammatory interleukin 10 and of proapoptotic IL‐18 in patients with chronic hepatitis C treated with interferon alpha and ribavirin
Journal of Viral Hepatitis - Tập 13 Số 4 - Trang 230-234 - 2006
Eva Marín Serrano, C Rodríguez-Ramos, Fernando Dı́az, L Martín-Herrera, J.A. Girón González
Summary.  The aim of this work was to analyse apoptosis rate, measured by the serum levels of proapoptotic interleukin (IL)‐18 and of soluble Fas (sFas), as well as of anti‐inflammatory IL‐10, in patients with chronic hepatitis C, at baseline and after treatment with interferon alpha and ribavirin. Twenty‐seven patients with biopsy‐proven chronic hepatitis C were stu...... hiện toàn bộ
Hepatitis C virus and the brain
Journal of Viral Hepatitis - Tập 19 Số 5 - Trang 301-306 - 2012
Nicola F. Fletcher, Jane A. McKeating
Summary.  Hepatitis C virus (HCV) is an enveloped, positive‐strand RNA virus of the family Flaviviridae that primarily infects hepatocytes, causing acute and chronic liver disease. HCV is also associated with a variety of extrahepatic symptoms including central nervous system (CNS) abnormalities, cognitive dysfunction, fatigue and depression. These symptoms do not co...... hiện toàn bộ
Community‐based real‐world treatment outcomes of sofosbuvir/ledipasvir in Asians with chronic hepatitis C virus genotype 6 in the United States
Journal of Viral Hepatitis - Tập 24 Số 1 - Trang 17-21 - 2017
R. J. Wong, M. T. Nguyen, H. N. Trinh, A. Huynh, M. T. Ly, H. A. Nguyen, K. K. Nguyen, J. Yang, R. T. Garcia, B. Levitt, E. Silveira, R. G. Gish
Summary Sofosbuvir/ledipasvir (SOF/LDV) is the first all‐oral ribavirin‐free treatment approved for chronic hepatitis C virus (HCV) genotype 6, offering a safe and highly efficacious treatment option. Large studies evaluating real‐world outcomes of this regimen are lacking. We aim to evaluate real‐world treatment outcomes for HCV genotype 6. A retrospective cohort study evaluated 65 adults (age ≥1...... hiện toàn bộ
#direct‐acting antivirals #hepatitis C virus #sustained virologic response
Incidence of Hepatitis A in Argentina after vaccination
Journal of Viral Hepatitis - Tập 15 Số s2 - Trang 47-50 - 2008
M Vacchino
Summary.  In Argentina, the annual incidence rate of reported hepatitis A disease ranged from 70.5 to 173.8 per 100 000 during 1995–2004. A single dose universal hepatitis A immunization program aimed at children aged 12 months was started in June 2005. The aim was to observe the impact of universal vaccination against hepatitis A in Argentina. A longitudinal analysi...... hiện toàn bộ
Impact of viral hepatitis aetiology on survival outcomes in hepatocellular carcinoma: A large multicentre cohort study
Journal of Viral Hepatitis - Tập 24 Số 11 - Trang 982-989 - 2017
S. Mgaieth, William Kemp, Paul Gow, Michael Fink, John Lubel, Amanda Nicoll, Alessia Gazzola, Thai Hong, Marno Ryan, Virginia Knight, Anouk Dev, Siddharth Sood, Sally Bell, Eldho Paul, Stuart K. Roberts
SummaryWhile HBV and HCV are risk factors for HCC, uncertainty exists as to whether these viral infections have prognostic significance in HC...... hiện toàn bộ
Association of TNF‐alpha promoter polymorphisms with the outcomes of hepatitis B virus infection in Chinese Han population
Journal of Viral Hepatitis - Tập 13 Số 9 - Trang 618-624 - 2006
Tian Du, Xinyao Guo, Xi‐Lin Zhu, Jin Li, L.‐P. Lu, J. R. Gao, Chunyan Gou, Zheyi Li, Y. Liu, H. Li
Summary.  Host genetic factors and environment factors including hepatitis B virus (HBV) genotypes are widely studied for the different outcomes of HBV infection. Recent studies suggest that tumour necrosis factor‐alpha (TNF‐alpha) plays a pivotal role in the viral clearance and host immune response to HBV, and the capacity for TNF‐alpha production in individuals is ...... hiện toàn bộ
Cytokine profile of peripheral blood mononuclear cells from patients with different outcomes of hepatitis C virus infection
Journal of Viral Hepatitis - Tập 12 Số 5 - Trang 525-530 - 2005
Annagiulia Gramenzi, Pietro Andreoné, E. Loggi, Francesco Giuseppe Foschi, C. Cursaro, Marzia Margotti, Maurizio Biselli, M. Bernardi
Summary.  The relationship between the balance of helper T‐cell type 1 (Th1) or type 2 (Th2) cytokines and the clinical course of hepatitis C virus (HCV) infection is unclear. We evaluated Th1 [interleukin (IL)‐2, interferon‐gamma (IFN‐γ)] and Th2 cytokine (IL‐4, IL‐10) and 2,5‐oligoadenylate synthetase (OAS, an IFN‐induced antiviral protei...... hiện toàn bộ
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