Journal of Venomous Animals and Toxins Including Tropical Diseases

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Viper bites complicate chronic agrochemical nephropathy in rural Sri Lanka
Journal of Venomous Animals and Toxins Including Tropical Diseases - Tập 20 - Trang 1-5 - 2014
Anjana Silva, Rivikelum Samarasinghe, Senaka Pilapitiya, Niroshana Dahanayake, Sisira Siribaddana
Snakebite is a common occupational health hazard among Sri Lankan agricultural workers, particularly in the North Central Province. Viperine snakes, mainly Russell’s viper envenomation, frequently lead to acute renal failure. During the last two decades, an agrochemical nephropathy, a chronic tubulointerstitial disease has rapidly spread over this area leading to high morbidity and mortality. Most...... hiện toàn bộ
The modular nature of bradykinin-potentiating peptides isolated from snake venoms
Journal of Venomous Animals and Toxins Including Tropical Diseases - Tập 23 - Trang 1-8 - 2017
Juliana Mozer Sciani, Daniel Carvalho Pimenta
Bradykinin-potentiating peptides (BPPs) are molecules discovered by Sergio Ferreira – who found them in the venom of Bothrops jararaca in the 1960s – that literally potentiate the action of bradykinin in vivo by, allegedly, inhibiting the angiotensin-converting enzymes. After administration, the global physiological effect of BPP is the decrease of the blood pressure. Due to this interesting effec...... hiện toàn bộ
Ergosterol isolated from the basidiomycete Pleurotus salmoneostramineus affects Trypanosoma cruzi plasma membrane and mitochondria
Journal of Venomous Animals and Toxins Including Tropical Diseases - Tập 23 - Trang 1-10 - 2017
Tatiana Rodrigues Alexandre, Marta Lopes Lima, Mariana Kolos Galuppo, Juliana Tonini Mesquita, Matilia Ana do Nascimento, Augusto Leonardo dos Santos, Patricia Sartorelli, Daniel Carvalho Pimenta, Andre Gustavo Tempone
Major drawbacks of the available treatment against Chagas disease (American trypanosomiasis) include its toxicity and therapeutic inefficiency in the chronic phase of the infection, which makes it a concern among neglected diseases. Therefore, the discovery of alternative drugs for treating chronic Chagas disease requires immediate action. In this work, we evaluated the mushroom Pleurotus salmoneo...... hiện toàn bộ
Efficacy of sertraline against Trypanosoma cruzi: an in vitro and in silico study
Journal of Venomous Animals and Toxins Including Tropical Diseases - Tập 24 - Trang 1-12 - 2018
Daiane Dias Ferreira, Juliana Tonini Mesquita, Thais Alves da Costa Silva, Maiara Maria Romanelli, Denise da Gama Jaen Batista, Cristiane França da Silva, Aline Nefertiti Silva da Gama, Bruno Junior Neves, Cleber Camilo Melo-Filho, Maria de Nazare Correia Soeiro, Carolina Horta Andrade, Andre Gustavo Tempone
Drug repurposing has been an interesting and cost-effective approach, especially for neglected diseases, such as Chagas disease. In this work, we studied the activity of the antidepressant drug sertraline against Trypanosoma cruzi trypomastigotes and intracellular amastigotes of the Y and Tulahuen strains, and investigated its action mode using cell biology and in silico approaches. Sertraline dem...... hiện toàn bộ
Structural determinants of the hyperalgesic activity of myotoxic Lys49-phospholipase A2
Journal of Venomous Animals and Toxins Including Tropical Diseases - Tập 23 - Trang 1-9 - 2017
Vanessa Olzon Zambelli, Lucimara Chioato, Vanessa Pacciari Gutierrez, Richard John Ward, Yara Cury
Bothropstoxin-I (BthTx-I) is a Lys49-phospholipase A2 (Lys49-PLA2) from the venom of Bothrops jararacussu, which despite of the lack of catalytic activity induces myotoxicity, inflammation and pain. The C-terminal region of the Lys49-PLA2s is important for these effects; however, the amino acid residues that determine hyperalgesia and edema are unknown. The aim of this study was to characterize th...... hiện toàn bộ
Deinagkistrodon acutus envenomation: a report of three cases
Journal of Venomous Animals and Toxins Including Tropical Diseases - - 2017
Chin-Lung Cheng, Yan‐Chiao Mao, Po‐Yu Liu, Liao-Chun Chiang, Shu‐Chen Liao, Chen-Chang Yang
Seroprevalence of flaviviruses antibodies in water buffaloes (Bubalus bubalis) in Brazilian Amazon
Journal of Venomous Animals and Toxins Including Tropical Diseases - Tập 20 - Trang 1-3 - 2014
Alexandre R Casseb, Andrea V Cruz, Iroleide S Jesus, Jannifer O Chiang, Lívia C Martins, Sandro P Silva, Daniele F Henriques, Livia MN Casseb, Pedro Fernando C Vasconcelos
The state of Pará encompasses 26% of Brazilian Amazon where an enormous diversity of arboviruses has been found. This study aimed to assess the prevalence and distribution of hemagglutination-inhibition antibodies against antigens of six Flavivirus (yellow fever virus, Ilheus virus, Saint Louis encephalitis virus, Cacipacore virus, Bussuquara virus and Rocio virus) in water buffaloes in Pará state...... hiện toàn bộ
Erratum to: Pediatric suppurative parotitis caused by Burkholderia pseudomallei
Journal of Venomous Animals and Toxins Including Tropical Diseases - Tập 23 - Trang 1-1 - 2017
Zengzhen Fu, Yingzi Lin, Qiang Wu, Qianfeng Xia
Lepromatous leprosy and perianal tuberculosis: a case report and literature review
Journal of Venomous Animals and Toxins Including Tropical Diseases - Tập 20 - Trang 1-6 - 2014
Maria Rita Parise-Fortes, Joel Carlos Lastória, Silvio Alencar Marques, Maria Stella Ayres Putinatti, Hamilton Ometto Stolf, Mariângela Ester Alencar Marques, Vidal Haddad
Leprosy is a chronic infectious disease caused by Mycobacterium leprae, a microorganism that usually affects skin and nerves. Although it is usually well-controlled by multidrug therapy (MDT), the disease may be aggravated by acute inflammatory reaction episodes that cause permanent tissue damage particularly to peripheral nerves. Tuberculosis is predominantly a disease of the lungs; however, it m...... hiện toàn bộ
Snake venom L-amino acid oxidases: an overview on their antitumor effects
Journal of Venomous Animals and Toxins Including Tropical Diseases - Tập 20 - Trang 1-7 - 2014
Tássia R Costa, Sandra M Burin, Danilo L Menaldo, Fabíola A de Castro, Suely V Sampaio
The L-amino acid oxidases (LAAOs) constitute a major component of snake venoms and have been widely studied due to their widespread presence and various effects, such as apoptosis induction, cytotoxicity, induction and/or inhibition of platelet aggregation, hemorrhage, hemolysis, edema, as well as antimicrobial, antiparasitic and anti-HIV activities. The isolated and characterized snake venom LAAO...... hiện toàn bộ
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