Seroprevalence of flaviviruses antibodies in water buffaloes (Bubalus bubalis) in Brazilian Amazon

Alexandre R Casseb1,2, Andrea V Cruz1, Iroleide S Jesus1, Jannifer O Chiang3, Lívia C Martins3, Sandro P Silva4, Daniele F Henriques3, Livia MN Casseb3, Pedro Fernando C Vasconcelos3,5
1Institute of Health and Livestock Production, Federal Rural University of the Amazon (UFRA), Belém, Brazil
2Instituto da Saúde e Produção Animal, Universidade Federal Rural da Amazônia, Belém, Brazil
3Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Ananindeua, Brazil
4Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil
5Department of Pathology, State University of Pará (UEPA), Belém, Brazil

Tóm tắt

The state of Pará encompasses 26% of Brazilian Amazon where an enormous diversity of arboviruses has been found. This study aimed to assess the prevalence and distribution of hemagglutination-inhibition antibodies against antigens of six Flavivirus (yellow fever virus, Ilheus virus, Saint Louis encephalitis virus, Cacipacore virus, Bussuquara virus and Rocio virus) in water buffaloes in Pará state, Brazil. The prevalence of antibodies in these farm animals is important to determine the circulating arboviruses. All investigated arboviruses were detected in the species studied and our results indicate that water buffaloes are susceptible to Flavivirus infection. Furthermore, there is solid evidence of active circulation of these viruses in the Brazilian Amazon. Water buffaloes showed higher prevalence of heterotypic antibody reactions and we hypothesized that they can serve as sentinels to detect the movement of such arboviruses in the Brazilian Amazon.

Tài liệu tham khảo

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