The Hemostatic Effects of Warfarin Titration in Post CABG Patients in Comparison to Placebo TreatmentJournal of Thrombosis and Thrombolysis - Tập 11 - Trang 143-149 - 2001
Jeanine M. Walenga, Debra Hoppensteadt, Roque Pifarre´, Norma Lynn Fox, Sandra Forman, Donald B. Hunninghake, Lucien Campeau, J. Alan Herd, Byron J. Hoogwerf, Ann Hickey, Jeffrey L. Probstfield, Michael L. Terrin
Background: Since coronary artery bypass graft patients remain at risk of coronary artery and bypass graft occlusion after successful surgery, adjunct treatment regimens are under investigation. In a study of the patients of the multicenter Post Coronary Artery Bypass Graft (Post CABG) Trial, 1[emsp4 ]mg warfarin was found to have no important effect on coagulation parameters.
Study design: The ...... hiện toàn bộ
Stroke and presence of patent foramen ovale in sickle cell diseaseJournal of Thrombosis and Thrombolysis - Tập 52 - Trang 889-897 - 2021
Constantina Aggeli, Kali Polytarchou, Yannis Dimitroglou, Dimitrios Patsourakos, Sophia Delicou, Sophia Vassilopoulou, Eleftherios Tsiamis, Kostas Tsioufis
Sickle cell disease (SCD) is an inherited monogenic hemoglobinopathy characterized by formation of sickle erythrocytes under conditions of deoxygenation. Sickle erythrocytes can lead to thrombus formation and vaso-occlusive episodes that may result in hemolytic anemia, pain crisis and multiple organ damage. Moreover, SCD is characterized by endothelial damage, increased inflammatory response, plat...... hiện toàn bộ
Guided de-escalation of DAPT in acute coronary syndrome patients undergoing percutaneous coronary intervention with BVS implantation: a post-hoc analysis from the randomized TROPICAL-ACS trialJournal of Thrombosis and Thrombolysis - Tập 47 - Trang 427-435 - 2019
Lukasz Koltowski, Mariusz Tomaniak, Lisa Gross, Bartosz Rymuza, Michal Kowara, Radoslaw Parma, Anna Komosa, Mariusz Klopotowski, Claudius Jacobshagen, Tommaso Gori, Daniel Aradi, Kurt Huber, Martin Hadamitzky, Steffen Massberg, Maciej Lesiak, Krzysztof J. Filipiak, Adam Witkowski, Grzegorz Opolski, Zenon Huczek, Dirk Sibbing
To investigate the safety and efficacy of an early platelet function testing (PFT)-guided de-escalation of dual antiplatelet treatment (DAPT) in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI) with bioresorbable vascular scaffolds (BVS). Early DAPT de-escalation is a new non-inferior alternative to 12-months DAPT in patients with biomarker positive ACS tr...... hiện toàn bộ
Platinoid effects on human plasmatic coagulation kinetics: a viscoelastic analysisJournal of Thrombosis and Thrombolysis - Tập 51 - Trang 577-583 - 2021
Vance G. Nielsen
In recent years a variety of metals (cadmium, chromium, copper, iron) have been demonstrated to modulate coagulation in vitro and in vivo. One group of metals, the platinoids, have not been assessed, and such investigation is justified given the thromboembolic phenomena associated with platinum-based chemotherapy. Thus, the goal of the present investigation was to assess the effects of carboplatin...... hiện toàn bộ
Comparison of ruptured coronary plaques in patients with unstable and stable clinical presentationJournal of Thrombosis and Thrombolysis - Tập 32 - Trang 150-157 - 2011
Cheol Whan Lee, Chan-Sik Park, Ilseon Hwang, Hyangsin Lee, Duk-Woo Park, Su-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Seong-Wook Park, Seung-Jung Park
It remains uncertain why some plaque ruptures trigger acute coronary syndrome (ACS), whereas others do not. We investigated the anatomic features and tissue factor (TF) expression at the sites of plaque rupture in 42 patients presenting with ACS (n = 23) or stable angina (n = 19). Intravascular ultrasound examination was performed before directional coronary atherectomy. Specimens were stained wit...... hiện toàn bộ