Image-guided adaptive radiotherapy improves acute toxicity during intensity-modulated radiation therapy for head and neck cancerJournal of Radiation Oncology - Tập 7 - Trang 139-145 - 2017
Allen M. Chen, Taeko Yoshizaki, Sophia Hsu, Argin Mikaeilian, Minsong Cao
The purpose of this study was to evaluate the impact of an image-guided adaptive re-planning strategy on patients treated by intensity-modulated radiotherapy (IMRT) for head and neck cancer. Among 198 patients with head and neck cancer comprising the primary study population, 79 (40%) underwent adaptive radiotherapy with modification of the original IMRT midway during treatment. The incidence of g...... hiện toàn bộ
Stereotactic radiosurgery for brain metastases: current status and future directionsJournal of Radiation Oncology - Tập 1 - Trang 245-253 - 2012
Nicholas S. Boehling, Eric L. Chang, Lijun Ma, Nicolas Phan, Robert Yeung, Arjun Sahgal
The purpose of this review is to provide a comprehensive summary of the management of brain metastases, and the role of stereotactic radiosurgery (SRS), based on the reported randomized controlled trials. An overview of SRS technology is also provided with a focus on the technologic innovations leading to frameless SRS. SRS as it applies to the post-operative patient is also discussed as this trea...... hiện toàn bộ
Radiosensitization of cervical cancer xenografts by arsenic trioxide and the role of VEGF and Ku70Journal of Radiation Oncology - Tập 1 - Trang 299-304 - 2012
Qinlan Ren, Jeremy Tey, Xiaoyu Li, Yu Wu, Hongbin Deng, Lan Han
The aim of this study is to explore the effect of arsenic trioxide (As2O3) on radiosensitivity in cervical carcinoma xenografts and the possible underlying mechanisms of vascular endothelial growth factor (VEGF) and Ku autoantigen protein p70 (Ku70). The tumor-bearing C57BL/6mouse model was established by injecting U14 cervical carcinoma cells into the right infra-axillary dermis of 40 mice. The m...... hiện toàn bộ
Ventricular violation increases the risk of leptomeningeal disease in cavity-directed radiosurgery treated patientsJournal of Radiation Oncology - Tập 8 - Trang 23-29 - 2018
Bradley DePaoli, Yair M. Gozal, Luke E. Pater, John C. Breneman, Ronald E. Warnick, Joshua Elson, Timothy D. Struve
Stereotactic radiosurgery is increasingly used in patients with limited brain metastases and good baseline performance to avoid the toxicities of whole brain radiotherapy (WBRT). Patients with resected brain metastases are undergoing cavity-directed radiosurgery, withholding WBRT. Multiple institutions have published concerning incidences of leptomeningeal disease (LMD) when using this approach. W...... hiện toàn bộ
Reirradiation of recurrent salivary gland malignancies with fractionated stereotactic body radiation therapyJournal of Radiation Oncology - Tập 1 - Trang 147-153 - 2012
Sana D. Karam, James W. Snider, Hongkun Wang, Margaux Wooster, Christopher Lominska, John Deeken, Kenneth Newkirk, Bruce Davidson, K. William Harter
The purpose of this study was to review a single-institution experience with the reirradiation of recurrent salivary gland tumors using fractionated stereotactic radiosurgery (SBRT). Between 2003 and 2011, 18 patients diagnosed with recurrent, previously irradiated, salivary gland carcinomas were treated with SBRT reirradiation. Median age was 68 for all patients with most tumors being of major sa...... hiện toàn bộ
Radiotherapy for adenoid cystic carcinomas of the head and neck: clinical outcomes and patterns of failureJournal of Radiation Oncology - Tập 3 - Trang 49-56 - 2013
David B. Shultz, Youssef H. Zeidan, James D. Murphy, Wendy Hara, Michael J. Kaplan, Quynh-Thu Le, Daniel T. Chang
Our goal was to evaluate the use of postoperative or definitive radiotherapy for primary adenoid cystic carcinoma in the head and neck and to determine prognostic variables. From April 1973 to June 2009, 44 patients were treated with radiotherapy at Stanford University, 3 definitively and 41 postoperatively. Median follow-up was 59 months (range, 10–246) for all patients and 56 months for living p...... hiện toàn bộ
Therapeutic value of postmastectomy radiation therapy for T1–2 breast cancer with 1–3 positive lymph nodesJournal of Radiation Oncology - Tập 8 - Trang 323-328 - 2019
Yuri Kimura, Shinsuke Sasada, Noriko Goda, Keiko Kajitani, Akiko Emi, Norio Masumoto, Takayuki Kadoya, Morihito Okada
Postmastectomy radiation therapy (PMRT) reduces locoregional recurrence (LRR) and breast cancer mortality for node-positive breast cancer, but its indication remains controversial in patients with 1–3 positive lymph nodes. We retrospectively analyzed LRR and survival rates in T1–2 breast cancer with 1–3 positive lymph nodes according to PMRT. The prognostic factors and the impact of the current st...... hiện toàn bộ