Irisin được dự đoán mạnh mẽ hơn bởi tiềm năng oxy hóa cơ bắp so với khối lượng mỡ ở nam giới không mắc tiểu đường Dịch bởi AI Journal of Physiology and Biochemistry - Tập 71 - Trang 559-568 - 2015
Claire Huth, Marie-Julie Dubois, André Marette, Angelo Tremblay, S. John Weisnagel, Michel Lacaille, Pascale Mauriège, Denis R. Joanisse
Nhiều tranh cãi bao quanh hormone peptide irisin. Mặc dù được coi là một myokine thúc đẩy quá trình chuyển hóa mỡ ở chuột, vai trò của nó ở người vẫn chưa rõ ràng. Các kết quả mâu thuẫn cũng đã được phát hiện liên quan đến mối quan hệ giữa mỡ cơ thể hoặc sức khỏe chuyển hóa và nồng độ irisin trong huyết tương ở người. Chúng tôi đã điều tra mối quan hệ giữa nồng độ irisin và thành phần cơ thể (cân ...... hiện toàn bộ
#hormone peptide #irisin #myokine #mỡ cơ thể #sức khỏe chuyển hóa #độ nhạy insulin #hoạt động cơ bắp #citrate synthase
Rapid stimulation of human renal ENaC by cAMP in Xenopus laevis oocytesJournal of Physiology and Biochemistry - Tập 69 - Trang 419-427 - 2012
G. G. Robins, K. A. MacLennan, R. P. Boot-Handford, G. I. Sandle
Among the compensatory mechanisms restoring circulating blood volume after severe haemorrhage, increased vasopressin secretion enhances water permeability of distal nephron segments and stimulates Na+ reabsorption in cortical collecting tubules via epithelial sodium channels (ENaC). The ability of vasopressin to upregulate ENaC via a cAMP-dependent mechanism in the medium to long term is well esta...... hiện toàn bộ
Differences in macrophage polarization in the adipose tissue of obese mice under various levels of exercise intensityJournal of Physiology and Biochemistry - Tập 76 - Trang 159-168 - 2020
Kyung-Wan Baek, Da-In Lee, Shin Ae Kang, Hak Sun Yu
Animal studies have demonstrated that the ratio of M1 (M1Φ) to M2 (M2Φ) macrophage-specific gene expression in adipose tissue (AT) may be altered by chronic exercise; however, whether macrophage polarization is induced under these conditions has not yet been reported. Therefore, this study aimed to investigate the effect of chronic exercise on M1Φ/M2Φ polarization in the AT of high-fat diet (HFD)-...... hiện toàn bộ
Hepatocellular carcinoma induced by hepatocyte Pten deletion reduces BAT UCP-1 and thermogenic capacity in mice, despite increasing serum FGF-21 and iWAT browningJournal of Physiology and Biochemistry - Tập 79 - Trang 731-743 - 2023
Álbert S. Peixoto, Mayara F. Moreno, Érique Castro, Luiz A. Perandini, Thiago Belchior, Tiago E. Oliveira, Thayna S. Vieira, Gustavo R. Gilio, Caroline A. Tomazelli, Bianca F. Leonardi, Milene Ortiz-Silva, Luciano P. Silva Junior, Eduardo H. Moretti, Alexandre A. Steiner, William T. Festuccia
Hepatocellular carcinoma (HCC) markedly enhances liver secretion of fibroblast growth factor 21 (FGF-21), a hepatokine that increases brown and subcutaneous inguinal white adipose tissues (BAT and iWAT, respectively) uncoupling protein 1 (UCP-1) content, thermogenesis and energy expenditure. Herein, we tested the hypothesis that an enhanced BAT and iWAT UCP-1-mediated thermogenesis induced by high...... hiện toàn bộ
Glucose and glutamine metabolism control by APC and SCF during the G1-to-S phase transition of the cell cycleJournal of Physiology and Biochemistry - Tập 70 - Trang 569-581 - 2014
Irving Omar Estévez-García, Verónica Cordoba-Gonzalez, Eleazar Lara-Padilla, Abel Fuentes-Toledo, Ramcés Falfán-Valencia, Rafael Campos-Rodríguez, Edgar Abarca-Rojano
Recent studies have given us a clue as to how modulations of both metabolic pathways and cyclins by the ubiquitin system influence cell cycle progression. Among these metabolic modulations, an aerobic glycolysis and glutaminolysis represent an initial step for metabolic machinery adaptation. The enzymes 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) and glutaminase-1 (GLS1) maintai...... hiện toàn bộ
Effects of different doses of resveratrol on body fat and serum parameters in rats fed a hypercaloric dietJournal of Physiology and Biochemistry - Tập 65 - Trang 369-376 - 2009
M. T. Macarulla, G. Alberdi, S. Gómez, I. Tueros, C. Bald, V. M. Rodríguez, J. A. Martínez, M. P. Portillo
Recently resveratrol, a compound naturally occurring in various plants, has been proposed as a potential anti-obesity compound. The aim of the present work was to analyse the effects of different doses of resveratrol on body fat and serum parameters in rats. Thirty-two male Sprague-Dawley rats were randomly divided into four groups and fed on a hypercaloric diet for 6 weeks. The doses oftrans-resv...... hiện toàn bộ
Ghrelin prevents lethality in a rat endotoxemic model through central effects on the vagal pathway and adenosine A2B signalingJournal of Physiology and Biochemistry - - 2023
Sho Igarashi, Tsukasa Nozu, Masatomo Ishioh, Takuya Funayama, Chihiro Sumi, Takeshi Saito, Yasumichi Toki, Mayumi Hatayama, Masayo Yamamoto, Motohiro Shindo, Hiroki Tanabe, Toshikatsu Okumura
Accumulating evidence suggest that ghrelin plays a role as an antiseptic peptide. The present study aimed to clarify whether the brain may be implicated ghrelin’s antiseptic action. We examined the effect of brain ghrelin on survival in a novel endotoxemic model achieved by treating rats with lipopolysaccharide (LPS) and colchicine. The observation of survival stopped three days after chemicals’ i...... hiện toàn bộ