Journal of Physiology and Biochemistry
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Growth hormone (GH) differentially regulates NF-kB activity in preadipocytes and macrophages: implications for GH’s role in adipose tissue homeostasis in obesity
Journal of Physiology and Biochemistry - Tập 70 - Trang 433-440 - 2014
Adipose tissue remodeling in obesity involves macrophage infiltration and chronic inflammation. NF-kB-mediated chronic inflammation of the adipose tissue is directly implicated in obesity-associated insulin resistance. We have investigated the effect of growth hormone (GH) on NF-kB activity in preadipocytes (3T3-F442A) and macrophages (J774A.1). Our studies indicate that whereas GH increases NF-kB...... hiện toàn bộ
An experimental model of partial insulin-like growth factor-1 deficiency in mice
Journal of Physiology and Biochemistry - Tập 70 - Trang 129-139 - 2013
Insulin-like growth factor-1 (IGF-1) is responsible for many systemic growth hormone (GH) functions although it has an extensive number of inherent activities (anabolic, cytoprotective, and anti-inflammatory). The potential options for IGF-1 therapy arise as a promising strategy in a wide list of human diseases. However, deeper studies are needed from a suitable animal model. All human conditions ...... hiện toàn bộ
Sexual dimorphism in obesity-related genes in the epicardial fat during aging
Journal of Physiology and Biochemistry - Tập 73 - Trang 215-224 - 2016
Aging increases the risk of cardiovascular disease and metabolic syndrome. Alterations in epicardial fat play an important pathophysiological role in coronary artery disease and hypertension. We investigated the impact of normal aging on obesity-related genes in epicardial fat. Sex-specific changes in obesity-related genes with aging in epicardial fat (EF) were determined in young (6 months) and o...... hiện toàn bộ
P-glycoprotein, glutathione and glutathione S-transferase increase in a colon carcinoma
Journal of Physiology and Biochemistry - - 2000
Lactate ameliorates palmitate-induced impairment of differentiative capacity in C2C12 cells through the activation of voltage-gated calcium channels
Journal of Physiology and Biochemistry - - 2024
Palmitic acid (PA), a saturated fatty acid enriched in high-fat diet, has been implicated in the development of skeletal muscle regeneration dysfunction. This study aimed to examine the effects and mechanisms of lactate (Lac) treatment on PA-induced impairment of C2C12 cell differentiation capacity. Furthermore, the involvement of voltage-gated calcium channels in this context was examined. In thi...... hiện toàn bộ
Effect of recombinant human GH and GHRH on plasma metabolite levels in rainbow trout (Oncorhynchus mykiss)
Journal of Physiology and Biochemistry - Tập 60 - Trang 211-218 - 2004
The aim of the present work was to study metabolic changes in rainbow trout treated with preparations of human recombinants of growth hormone (rhGH) and GH-releasing hormone (rhGHRH), by analysing time course variations in plasma metabolite levels. Trouts were given the hormones by intraperitoneal injection in a single dose (rhGH: 0.5 μg/g b.w.; rhGHRH: 0.06μg/g b.w.) or as a weekly injection over...... hiện toàn bộ
25-Hydroxyvitamin D levels of children are inversely related to adiposity assessed by body mass index
Journal of Physiology and Biochemistry - Tập 74 - Trang 111-118 - 2017
Vitamin D deficiency is associated with wide range of pathologies. Some evidences have shown that low vitamin D circulating levels in children and adolescent are related to fat mass and obesity. The objectives of the present study were to characterize vitamin D status in children and adolescents and to determine if serum 25-hydroxyvitamin D (25(OH)D) concentration is related to adiposity assessed ...... hiện toàn bộ
Correction: Irisin improves adiposity and exercise tolerance in a rat model of postmenopausal obesity through enhancing adipo-myocyte thermogenesis
Journal of Physiology and Biochemistry - Tập 79 - Trang 683-683 - 2023
Suplemento de creatina y rendimiento en 6 carreras consecutivas máximas de 60 m
Journal of Physiology and Biochemistry - - 2004
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