Journal of Ocular Biology, Diseases, and Informatics

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Tumor necrosis factor-α-mediated severity of idiopathic retinal periphlebitis in young adults (Eales’ disease): implication for anti-TNF-α therapy
Journal of Ocular Biology, Diseases, and Informatics - Tập 3 - Trang 35-38 - 2010
Sandeep Saxena, Aditya B. Pant, Vinay K. Khanna, Kamlesh Singh, Rajendra K. Shukla, Carsten H. Meyer, Vijay K. Singh
Tumor necrosis factor-alpha (TNF-α) is a pleiotropic inflammatory cytokine. Tumor necrosis factor-alpha was evaluated in the serum samples of patients with idiopathic retinal periphlebitis in young adults (Eales’ disease). Retinal periphlebitis was graded according to a new grading system based on severity of inflammation (grade 1–4). Quantification of the TNF-α levels was carried out using ELISA ...... hiện toàn bộ
Comparative modeling of retinol-binding protein-3 and retinal S-antigen in Eales’ disease and prediction of their binding sites using computational methods
Journal of Ocular Biology, Diseases, and Informatics - - 2010
Anshul Tiwari, Ashish Chandra Trivedi, Prachi Srivastava, Aditya B. Pant, Sandeep Saxena
Hereditary hemorrhagic telangiectasia with multiple fusiform retinal aneurysms
Journal of Ocular Biology, Diseases, and Informatics - Tập 5 - Trang 48-50 - 2013
Nagihan Uğurlu, Selma Emre, Fatma Yülek, Emine Kalkan Akcay, Ahmet Sengun
Role of adenosine in diabetic retinopathy
Journal of Ocular Biology, Diseases, and Informatics - Tập 4 - Trang 19-24 - 2012
Gregory I. Liou, Saif Ahmad, Mohammad Naime, Nadeem Fatteh, Ahmed S. Ibrahim
In diabetic retinopathy (DR), abnormalities in vascular and neuronal function are closely related to the local production of inflammatory mediators whose potential source is microglia. Adenosine and its receptors have been shown to possess anti-inflammatory properties that have only recently been studied in DR. Here, we review recent studies that determined the roles of adenosine and its associate...... hiện toàn bộ
Association of contrast sensitivity with LogMAR visual acuity and glycosylated hemoglobin in non-insulin dependent diabetes mellitus
Journal of Ocular Biology, Diseases, and Informatics - Tập 3 - Trang 60-63 - 2010
Shaili Misra, Sandeep Saxena, Poonam Kishore, Shashi K. Bhasker, Arvind Misra, Carsten H. Meyer
A tertiary care center-based prospective case–control study was undertaken to evaluate the association of contrast sensitivity with LogMAR visual acuity and glycosylated hemoglobin (HbA1c) in 205 cases of non-insulin dependent diabetes mellitus and 115 controls. LogMAR visual acuity and contrast sensitivity were scored using ETDRS and Pelli-Robson charts, respectively. Bivariate correlation betwee...... hiện toàn bộ
Psychoneuroimmunology: application to ocular diseases
Journal of Ocular Biology, Diseases, and Informatics - Tập 2 Số 2 - Trang 84-93 - 2009
Lori M. Ventura
Comparative modeling of PON2 and analysis of its substrate binding interactions using computational methods
Journal of Ocular Biology, Diseases, and Informatics - Tập 3 - Trang 64-72 - 2011
Subramanian Barathi, Muralidaran Charanya, Shivashanmugam Muthukumaran, Narayanasamy Angayarkanni, Vetrivel Umashankar
Paraoxonase (PON) constitutes a family of calcium-dependent mammalian enzymes comprising of PON1, PON2, and PON3. PON family shares ~60% sequence homology. These enzymes exhibit multiple activities like paraoxonase, arylesterase, and lactonase in a substrate dependent manner. Decreased PON activity has been reported in diseases like cardiovascular disease, atherosclerosis, and diabetes. Even thoug...... hiện toàn bộ
Three-dimensional spectral domain optical coherence tomography in Stargardt disease and fundus flavimaculatus
Journal of Ocular Biology, Diseases, and Informatics - - 2012
Sandeep Saxena, Neha Mishra, Carsten H. Meyer
RPE barrier breakdown in diabetic retinopathy: seeing is believing
Journal of Ocular Biology, Diseases, and Informatics - Tập 4 - Trang 83-92 - 2011
Hui-Zhuo Xu, Zhiming Song, Shuhua Fu, Meili Zhu, Yun-Zheng Le
Diabetic retinopathy (DR) is a major complication of diabetes and a leading cause of blindness in working-age Americans. DR is traditionally regarded as a disorder of blood–retina barriers, and the leakage of blood content is a major pathological characteristic of the disease. While the breakdown of the endothelial barrier in DR has been investigated extensively, the vascular leakage through the r...... hiện toàn bộ
Alterations in “in vivo” histology of retina in bilateral chronic central serous chorioretinopathy after intravitreal bevacizumab
Journal of Ocular Biology, Diseases, and Informatics - - 2011
Sandeep Saxena, Apurva Jain
Tổng số: 67   
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