Journal of Neuroendocrinology
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Reproduction and Resistance to Stress: When and HowAbstract Environmental and social stresses have deleterious effects on reproductive function in vertebrates. Global climate change, human disturbance and endocrine disruption from pollutants are increasingly likely to pose additional stresses that could have a major impact on human society. Nonetheless, some populations of vertebrates (from fish to mammals) are able... ... hiện toàn bộ
Journal of Neuroendocrinology - Tập 15 Số 8 - Trang 711-724 - 2003
Functional Consequences of Morphological Neuroglial Changes in the Magnocellular Nuclei of the HypothalamusAbstract The supraoptic and paraventricular nuclei of the hypothalamus undergo reversible anatomical changes under conditions of intense neurohypophysial hormone secretion, such as lactation, parturition and chronic dehydration. This morphological remodelling includes a reduction in astrocytic coverage of neurones resulting in an increase in the number and extent of... ... hiện toàn bộ
Journal of Neuroendocrinology - Tập 14 Số 3 - Trang 241-246 - 2002
Mineralocorticoid receptor associates with pro‐inflammatory bias in the hippocampus of spontaneously hypertensive ratsDamage observed in the hippocampus of the adult spontaneously hypertensive rat (SHR ) resembles the neuropathology of mineralocorticoid‐induced hypertension, supporting a similar endocrine dysfunction in both entities. In the present study, we tested the hypothesis that increased expression of the hippocampal mineralocorticoid re... ... hiện toàn bộ
Journal of Neuroendocrinology - Tập 29 Số 7 - 2017
Modulatory Effects of Sex Steroid Hormones on Brain‐Derived Neurotrophic Factor‐Tyrosine Kinase B Expression during Adolescent Development in C57Bl/6 MiceSex steroid hormones and neurotrophic factors are involved in pruning and shaping the adolescent brain and have been implicated in the pathogenesis of neurodevelopmental disorders, including mental illness. We aimed to determine the association between altered levels of sex steroid hormones during adolescent development and neurotrophic signalling in the C57Bl/6 mouse. We first performed a... ... hiện toàn bộ
Journal of Neuroendocrinology - Tập 24 Số 5 - Trang 774-788 - 2012
Gonadotrophin‐Inhibitory Hormone: A Multifunctional NeuropeptideGonadotrophin‐inhibitory hormone (GnIH) was discovered 8 years ago in birds. Its identification raised the possibility that gonadotrophin‐releasing hormone (GnRH) is not the sole hypothalamic neuropeptide that directly influences pituitary gonadotrophin release. Initial studies on GnIH focused on the avian anterior pituitary as comprising the only physiological target of GnIH. There are no... ... hiện toàn bộ
Journal of Neuroendocrinology - Tập 21 Số 4 - Trang 276-281 - 2009
An Essential Role for Peptidergic Signalling in the Control of Circadian Rhythms in the Suprachiasmatic NucleiAbstract Two structurally related neuropeptides, pituitary adenylate cyclase‐activating polypeptide (PACAP), colocalized with glutamate in neurones of the retinohypothalamic tract, and vasoactive intestinal peptide (VIP), present in light‐responsive cells of the suprachiasmatic nuclei (SCN), appear to play distinct and important roles in the control of mammalian cir... ... hiện toàn bộ
Journal of Neuroendocrinology - Tập 15 Số 4 - Trang 335-338 - 2003
Diurnal Changes in the Expression of Genes Encoding for Arginine Vasotocin and Pituitary Pro‐opiomelanocortin in the Rainbow Trout (Oncorhynchus mykiss): Correlation with Changes in Plasma HormonesUsing quantitative in ‐ situ hybridization, this study monitored diurnal changes in the abundance of the gene transcripts of two corticotropin‐releasing peptides, arginine vasotocin (AVT) and isotocin in hypothalamic neurones, and of pro‐opiomelanocortin (POMC) mRNA in the pituitary of the rainbow trout (... hiện toàn bộ
Journal of Neuroendocrinology - Tập 10 Số 12 - Trang 937-943 - 1998
Serum Testosterone Levels in Males with Alzheimer's DiseaseAbstract This study aimed to investigate whether there are differences in serum testosterone levels between male patients with Alzheimer's disease (AD) and cognitively normal male controls. Testosterone and sex hormone binding globulin (SHBG) levels were measured from 14 patients with mild to moderate AD and 16 age‐matched control males. The AD patients had higher l... ... hiện toàn bộ
Journal of Neuroendocrinology - Tập 16 Số 2 - Trang 95-98 - 2004
Attenuation of Hypothalamic‐Pituitary‐Adrenal Axis Stress Responses in Late Pregnancy: Changes in Feedforward and Feedback MechanismsAbstract The hypothalamic‐pituitary‐adrenal axis is hyporesponsive to stress in late pregnancy, exemplified as reduced adrenocorticotropic hormone (ACTH) and corticosterone responses to restraint, but the mechanisms are unknown. We investigated forward drive and negative feedback upon the hypothalamic‐pituitary‐adrenal axis in pregnant rats. Corticotropin‐releasing ... ... hiện toàn bộ
Journal of Neuroendocrinology - Tập 12 Số 8 - Trang 811-822 - 2000
The Influence of Gonadal Steroids on Pre‐Pro Melanin‐Concentrating Hormone mRNA in Female RatsMelanin‐concentrating hormone (MCH) may have a regulatory role in the control of luteinizing hormone (LH) release. We have investigated if gonadal steroids induce changes in the expression of pre‐pro MCH (ppMCH) that are associated with changes in the pattern of LH release. Using quantitative in‐situ hybridization histochemistry we have determined the effect of a... ... hiện toàn bộ
Journal of Neuroendocrinology - Tập 12 Số 1 - Trang 53-59 - 2000
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