Sex‐Related Differences in Dendritic Branching of Cells in the Prefrontal Cortex of Rats

Journal of Neuroendocrinology - Tập 3 Số 1 - Trang 95-99 - 1991
Bryan Kolb1, Jane Stewart2
1Department of Psychology, University of Lethbridge, Lethbridge, Alberta, Canada T1K 3M4
2Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montreal, Quebec, Canada H3G 1MB.

Tóm tắt

AbstractMale and female Sprague‐Dawley rats were given either gonadectomies or sham surgery on the day of birth. In adulthood they were sacrificed and prepared for Golgi‐Cox staining. Using a camera lucida technique, layer II/III pyramidal neurons were drawn in the anterior cingulate cortex areas 1 and 3 and the agranular insular cortex and the number of dendritic branches on the apical and basilar dendrites were then summarized. The results showed that the dendritic arbor of prefrontal cortical cells varied as a function of sex and neonatal gonadectomy. In cingulate 3, castrated males had a smaller arbor on the left relative to normal males, whereas, in cingulate 1 the reverse was found. In addition, females had less apical arbor than males in the cingulate areas, whereas, in the agranular insular cortex, females had greater apical arbor than the males. Furthermore, in this region, gonadectomized groups had less arbor than their respective control groups. Finally, in the agranular insular cortex, the dendritic arbor was greater in the left hemisphere.

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Tài liệu tham khảo

Diamond MC, 1984, Cerebral dominance: the biological foundations, 134

10.1016/0006-8993(89)91341-3

Juraska J, 1988, Neonatal castration of male rats affects the dendritic response to differential environments on granule neurons of the hippocampal dentate gyrus, Psychobiology, 16, 406, 10.3758/BF03327337

10.1016/0006-8993(82)91136-2

10.1016/S0163-1047(88)90354-8

10.1016/0014-4886(81)90087-X

Kolb B, 1982, Asymmetry in the cerebral hemispheres of the rat, mouse, rabbit and cat: the right hemisphere is larger, Exp Neurol, 78, 348, 10.1016/0014-4886(82)90053-X

10.1126/science.7188648

10.1016/0361-9230(86)90062-6

10.1016/0165-3806(84)90186-X

10.1016/0301-0082(89)90023-3

10.1016/0006-8993(77)90215-3

10.1016/0736-5748(84)90062-5

10.1016/0006-8993(73)90030-9

10.1007/978-3-642-70573-1

10.1210/endo-126-2-1112

10.1016/0165-0173(84)90018-3

Kolb B, 1990, The cerebral cortex of the rat, 437

10.1111/j.1365-2826.1991.tb00244.x

10.1016/0165-3806(83)90197-9

10.1016/0006-8993(79)90094-5

10.1002/cne.902690105

10.1016/0736-5748(87)90054-2

10.1016/0165-3806(87)90145-3

10.1002/cne.901870104

Clark AS, 1989, Gonadal hormones influence the emergence of cortical function in nonhuman primates, Behav Neurosci, 103, 1287, 10.1037/0735-7044.103.6.1287

10.1016/0166-4328(83)90032-3

10.1037/h0036969

Ferreirea A, 1987, Olfactory mechanisms in the control of maternal aggression, appetite, and fearfulness: effects of lesions to olfactory receptors, mediodorsal thalamic nucleus, and insular prefrontal cortex, Behav Neurosci, 101, 709, 10.1037/0735-7044.101.5.709

10.1016/S0091-6773(74)91924-5

10.1016/0166-4328(87)90069-6

10.1016/0014-4886(78)90276-5

10.1037/0735-7044.101.3.341

10.1016/S0163-1047(85)90310-3

10.1126/science.6849133

10.1016/0165-0270(81)90045-5

Coleman PD, 1968, Environmental effects on cortical dendritic fields. I. Rearing in the dark, J Anat, 102, 363

10.1007/978-1-4684-5691-2_12

10.1002/cne.901310207

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Journal of Neuroendocrinology

Tập 3 Số 1

95-99

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