Reproduction and Resistance to Stress: When and How Tập 15 Số 8 - Trang 711-724 - 2003
John C. Wingfield, RM Sapolsky
AbstractEnvironmental and social stresses have deleterious effects on reproductive function in vertebrates. Global climate change, human disturbance and endocrine disruption from pollutants are increasingly likely to pose additional stresses that could have a major impact on human society. Nonetheless, some populations of vertebrates (from fish to mammals) are able...... hiện toàn bộ Neurodevelopmental and Neurophysiological Actions of Thyroid Hormone Tập 20 Số 6 - Trang 784-794 - 2008
Graham R. Williams
For over 100 years, thyroid hormones have been known to be essential for neonatal neurodevelopment but whether they are required by the foetal brain remains a matter of controversy. For decades, the prevailing view was that thyroid hormones are not necessary until after birth because circulating levels in the foetus are very low and the placenta forms an efficient barrier to their transfer...... hiện toàn bộ Measurement of Immediate‐Early Gene Activation‐ c‐fos and Beyond Tập 20 Số 6 - Trang 665-672 - 2008
Krisztina Kovács
Immediate‐early genes (IEG) are powerful tools for identifying activated neurosecretory neurones and extended circuits that affect neuroendocrine functions. The generally acknowledged scenario is when cells became activated, IEGs expressed and IEG‐encoded transcription factors affect target gene expression. However, there are several examples in which: (i) neuronal activation occurs withou...... hiện toàn bộ Endocrine Disrupters: A Review of Some Sources, Effects, and Mechanisms of Actions on Behaviour and Neuroendocrine Systems Tập 24 Số 1 - Trang 144-159 - 2012
Cheryl A. Frye, Elisabetta Bo, Gemma Calamandrei, Laura Calzà, Francesco Dessì‐Fulgheri, Mercedes Fernández, Leonida Fusani, Olivier Kah, Małgorzata Kajta, Yann Le Page, Heather B. Patisaul, Aldina Venerosi, Anna K. Wójtowicz, Giancarlo Panzica
Some environmental contaminants interact with hormones and may exert adverse consequences as a result of their actions as endocrine disrupting chemicals (EDCs). Exposure in people is typically a result of contamination of the food chain, inhalation of contaminated house dust or occupational exposure. EDCs include pesticides and herbicides (such as dichlorodiphenyl trichloroethane or its me...... hiện toàn bộ