Journal of Natural Medicines
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Metabolic disease prevention and suppression of fat accumulation by Salacia reticulata
Journal of Natural Medicines - Tập 64 - Trang 266-274 - 2010
In Ayurvedic medicine, Salacia reticulata is known to be useful against various metabolic diseases, including diabetes and obesity. In this study, we attempted to clarify the antiobesity mechanism and the safety of S. reticulata in vivo and in vitro. We gave ordinary MF feed, alone or mixed with S. reticulata (0.3 or 1.0%), to Tsumura Suzuki obesity diabetes (TSOD) mice (spontaneous obese type II ...... hiện toàn bộ
Two new ɑ-pyrone derivatives from the endophytic Diaporthe sp. ECN371
Journal of Natural Medicines - Tập 76 - Trang 462-467 - 2022
Diaportholides A (1) and B (2), two polyketides with ɑ-pyrone moieties, were isolated from the cultures of an endophytic Diaporthe sp. ECN371 isolated from Orixa japonica, together with four known polyketides, phomopsolide B (3), phomopsolidones A (4) and B (5), and 5-[(1R)-1-hydroxyethyl]-γ-oxo-2-furanbutanoic acid (6). The structures of 1 and 2 were determined by extensive analysis of NMR and MS...... hiện toàn bộ
Main phenolic compounds from the flower of Trachelospermum asiaticum var. intermedium (Apocynaceae)
Journal of Natural Medicines - Tập 62 - Trang 354-355 - 2008
Six phenolic compounds were isolated from the flowers of Trachelospermum asiaticum var. intermedium (Apocynaceae). These structures were determined on the basis of spectral data.
Two new alkaloids from Crinum asiaticum var. japonicum
Journal of Natural Medicines - Tập 73 - Trang 648-652 - 2019
A new crinine-type alkaloid crijaponine A (1), a new galanthamine-type alkaloid crijaponine B (2), and 11 known alkaloids—ungeremine (3), lycorine (4), 2-O-acetyllycorine (5), 1, 2-O-diacetyllycorine (6), (−)-crinine (7), 11-hydroxyvittatine (8), hamayne (9), (+)-epibuphanisine (10), crinamine (11), yemenine A (12), and epinorgalanthamine (13)—were isolated from the rhizome and fruits of Crinum as...... hiện toàn bộ
New isoflavone glycosides from Iris spuria L. (Calizona) cultivated in Egypt
Journal of Natural Medicines - Tập 63 - Trang 91-95 - 2008
Two new isoflavone glycosides, tectorigenin 7-O-β-d-glucopyranoside-4′-O-[β-d-glucopyranosyl-(1″″ → 6′′′)-β-d-glucopyranoside] (1) and iristectorigenin B 4′-O-[β-d-glucopyranosyl-(1′′′ → 6″)-β-d-glucopyranoside] (2), together with 11 known compounds, including six isoflavones, tectorigenin 7-O-β-d-glucopyranoside-4′-O-β-d-glucopyranoside (3), tectorigenin 4′-O-[β-d-glucopyranosyl-(1′′′ → 6″)-β-d-g...... hiện toàn bộ
Three new xanthones from the leaves of Garcinia lancilimba
Journal of Natural Medicines - Tập 70 - Trang 173-178 - 2015
Three new prenylated xanthones, garcinexanthones G−I (1–3), together with fifteen known ones (4–18) were identified from the leaves of Garcinia lancilimba. Their structures were determined by extensive spectroscopic analyses. Most of the compounds exhibited inhibitory effects against HL-60 (human leukemia), A549 (human lung cancer), and MCF-7 (human breast cancer) cell lines. Among them, compounds...... hiện toàn bộ
Euchronin A–F isolated from the Arnebia euchroma (Royle) Johnst. and their anti-proliferative activities in vitro
Journal of Natural Medicines - Tập 78 - Trang 33-41 - 2023
Six new naphthoquinones, euchronin A–F (1–6) and nine known naphthoquinones (7–15), were isolated from the roots of Arnebia euchroma (Royle) Johnst. The structures of the new compounds were confirmed by extensive spectroscopic analyses, including UV, IR, HR-ESI–MS, 1D and 2D NMR. In the present study, we estimated the anti-proliferative activities of these compounds with HaCaT cells. The results i...... hiện toàn bộ
New 8,12;8,20-diepoxy-8,14-secopregnane hexa- and hepta-glycosides from the roots of Asclepias tuberosa
Journal of Natural Medicines - Tập 72 - Trang 347-356 - 2017
Previously, phytochemical investigation of the roots of Asclepias tuberosa (Asclepiadaceae) led to the isolation of some 8,12;8,20-diepoxy-8,14-secopregnane tri-, tetra-, and penta-glycosides. An additional eight new minor 8,12;8,20-diepoxy-8,14-secopregnane glycosides were afforded in the recent investigation of this plant. These glycosides consisted of six or seven 2,6-dideoxy-hexopyranoses toge...... hiện toàn bộ
Macrocarquinoids A–C, new meroterpenoids from Sargassum macrocarpum
Journal of Natural Medicines - - 2021
Seasonal variation in the content of a febrifugine and isofebrifugine alkaloid mixture in aerial parts of Hydrangea macrophylla var. Otaksa, with special reference to its antimalarial activity
Journal of Natural Medicines - Tập 61 - Trang 213-216 - 2006
Febrifugine and isofebrifugine alkaloid mixtures extracted from the leaves and buds of Hydrangea macrophylla var. Otaksa, collected during different months, in Japan, were quantified using high-performance liquid chromatography. Leaves collected during the flowering season, namely from June to August, contained 0.16–0.31 mg/g of the alkaloid mixture, whereas those collected from September to Decem...... hiện toàn bộ
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