Journal of Natural Medicines

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Species identification of Chinese medicinal plant Fallopia multiflora (Thunb.) Haraldson by suppression subtraction hybridization
Journal of Natural Medicines - Tập 68 - Trang 192-198 - 2013
Chuan-Jin Zheng, Shu-Jin Zhao, Li Shao
Fallopia multiflora (Thunb.) Haraldson, a traditional Chinese medicinal plant, has been extensively used in preparations of herbal medicine, health products and personal hygiene products. However, the clinical safety and efficiency of F. multiflora (Thunb.) Haraldson is impaired because of the existence of various adulterants. In this study, genomic DNA (gDNA) suppression subtract...... hiện toàn bộ
Synthesis and stereochemical determination of an antiparasitic pseudo-aminal type monoterpene indole alkaloid
Journal of Natural Medicines - Tập 70 - Trang 302-317 - 2016
Yoshihiko Noguchi, Tomoyasu Hirose, Aki Ishiyama, Masato Iwatsuki, Kazuhiko Otoguro, Toshiaki Sunazuka, Satoshi Ōmura
5-Nor stemmadenine alkaloids, isolated from the genus Tabernaemontana, display a range of bioactivity. 16-Hydroxy-16,22-dihydroapparicine, the active component of an extract from the Tabernaemontana sp. (dichotoma, elegans, and divaricate), exhibited potent antimalarial activity, representing the first such report of the antimalarial property of 5-nor stemmadenine alkaloids. We, therefore, decided...... hiện toàn bộ
Protective effect of Pueraria tuberosa DC. embedded biscuit on cisplatin-induced nephrotoxicity in mice
Journal of Natural Medicines - - 2012
Yamini B. Tripathi, Santosh Nagwani, P. C. Mishra, Alok Jha, Shashi Pandey-Rai
In vitro and in vivo antiherpetic effects of (1R,2R)-1-(5′-methylful-3′-yl)propane-1,2,3-triol
Journal of Natural Medicines - Tập 70 - Trang 217-224 - 2016
Kohei Sasaki, Kyoko Hayashi, Yuji Matsuya, Kenji Sugimoto, Jung-Bum Lee, Fumiya Kurosaki, Toshimitsu Hayashi
In this study, we demonstrated the in vitro and in vivo antiherpetic activities of a stable furan derivative, (1R,2R)-1-(5′-methylful-3′-yl)propane-1,2,3-triol (MFPT), which had originally been isolated from Streptomyces sp. strain FV60. In the present study, we synthesized MFPT from (5-methylfuran-3-yl)methanol in 6 steps for use in the experiments. MFPT showed potent in vitro antiviral activitie...... hiện toàn bộ
Anti-inflammatory activities of Ophiopogonis Radix on hydrogen peroxide-induced cellular senescence of normal human dermal fibroblasts
Journal of Natural Medicines - Tập 72 Số 4 - Trang 905-914 - 2018
Yumi Kitahiro, Atsushi Koike, Aska Sonoki, Mei Muto, Kazuo Ozaki, Makio Shibano
Discrimination of Curcuma species from Asia using intron length polymorphism markers in genes encoding diketide-CoA synthase and curcumin synthase
Journal of Natural Medicines - Tập 76 - Trang 69-86 - 2021
Qundong Liu, Shu Zhu, Shigeki Hayashi, Osamu Iida, Akihito Takano, Katsunori Miyake, Suchada Sukrong, Mangestuti Agil, Indira Balachandran, Norio Nakamura, Nobuo Kawahara, Katsuko Komatsu
Recently, Curcuma rhizome-related foods with claimed health benefits have been used worldwide; however, correct identification and quality assessment have not been conducted. Due to the wide distribution and morphological similarities of Curcuma species, the classification of some species is debated and nomenclature is inconsistent among countries. In this study, to elucidate specific molecular ma...... hiện toàn bộ
Ecological, phylogenetical, and pharmacognostical characteristics of Aconitum kiyomiense endemic to Hida highlands, Takayama city, Gifu Prefecture, Japan
Journal of Natural Medicines - Tập 73 - Trang 523-532 - 2019
Motoyasu Minami, Misaki Yasueda, Tomoyasu Shirako, Tetuo Murakami, Takako Mori, Taichi Fujii, Toshiyuki Atsumi, Toshiro Shibata, Yuichi Kadota
Aconitum kiyomiense Kadota (Ranunculaceae) is endemic to Takayama city, Gifu Prefecture, central Japan. We collected specimens from marshes and flood plains at altitudes ranging from 852 to 1085 m and from a new habitat consisting of a mesic meadow in the subalpine belt (1681 m). Glabrous pedicels and flowering sequence of inflorescence were used for identification, but intra-species variations in...... hiện toàn bộ
Hypotensive effect of the water extract of the leaves of Pseuderanthemum palatiferum
Journal of Natural Medicines - - 2011
Parirat Khonsung, Ampai Panthong, Natthakarn Chiranthanut, S. Intahphuak
A novel diterpenoid with a rearranged neoclerodane skeleton from Salvia leucantha CAV.
Journal of Natural Medicines - Tập 60 - Trang 206-209 - 2006
Yuji Narukawa, Keiichiro Hatano, Tadahiro Takeda
A new diterpenoid with a rearranged neoclerodane skeleton, spiroleucantholide (compound “S1”), along with four known diterpenoids—salvifaricin (compound “S2”), isosalvipuberulin (compound “S3”), salvileucantholide (compound “S4”), and salviandulin E (compound “S5”)—was isolated from the aerial parts of Salvia leucantha CAV.. The structures were established by spectroscopic methods, including the X...... hiện toàn bộ
Flavonoids isolated from the flowers of Pulsatilla flavescens and their anti-piroplasm activity
Journal of Natural Medicines - Tập 73 - Trang 633-640 - 2019
Dorj Ganchimeg, Badarch Batbold, Toshihiro Murata, Bekh-Ochir Davaapurev, Tserendorj Munkhjargal, Bumduuren Tuvshintulga, Keisuke Suganuma, Ikuo Igarashi, Buyanmandakh Buyankhishig, Kenroh Sasaki, Dulamjav Batsuren, Javzan Batkhuu
Pulsatilla species are known as “Yargui”, and their flowers are traditionally used in Mongolia as a tonic and for the treatment of inflammatory diseases. By chemical investigation of P. flavescens flowers, 21 flavonoids, including a new chalcone C-glucoside, chalconaringenin 2′-O-β-d-glucopyranosyl-5′-β-d-glucopyranoside, and two new flavanone C-glucosides, (2R)- and (2S)-naringenin 8-β-d-glucopyr...... hiện toàn bộ
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