Journal of Natural Medicines

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Longgu (Fossilia Ossis Mastodi) alters the profiles of organic and inorganic components in Keishikaryukotsuboreito
Journal of Natural Medicines - Tập 70 - Trang 483-491 - 2016
Kazuki Oguri, Masaya Kawase, Kazuo Harada, Kayoko Shimada-Takaura, Toshiharu Takahashi, Kyoko Takahashi
Longgu (Fossilia Ossis Mastodi) is a non-botanical crude drug, defined as “the ossified bone of large mammal” in the Japanese Pharmacopoeia sixteenth edition (JP16). It is a non-reproducible drug and is now facing the threat of exhaustion. To solve this problem, we aimed to clarify the role of longgu in Kampo prescriptions, which has not yet been scientifically ascertained. In this study, we focus...... hiện toàn bộ
Quality evaluation of medicinally-used Codonopsis species and Codonopsis Radix based on the contents of pyrrolidine alkaloids, phenylpropanoid and polyacetylenes
Journal of Natural Medicines - Tập 68 - Trang 326-339 - 2013
Jing-Yu He, Shu Zhu, Yukihiro Goda, Shao-Qing Cai, Katsuko Komatsu
A comparative study of 56 specimens of three medicinally-used Codonopsis taxa collected from China and 54 commercial samples of Codonopsis Radix available in Chinese, Japanese and Korean markets was carried out by quantitative analysis of seven major components: codonopyrrolidium B (1), codonopyrrolidium A (2), tangshenoside I (3), cordifolioidyne B (4), lobetyolinin (5), lobetyolin (6) and lobety...... hiện toàn bộ
Species identification of Chinese medicinal plant Fallopia multiflora (Thunb.) Haraldson by suppression subtraction hybridization
Journal of Natural Medicines - Tập 68 - Trang 192-198 - 2013
Chuan-Jin Zheng, Shu-Jin Zhao, Li Shao
Fallopia multiflora (Thunb.) Haraldson, a traditional Chinese medicinal plant, has been extensively used in preparations of herbal medicine, health products and personal hygiene products. However, the clinical safety and efficiency of F. multiflora (Thunb.) Haraldson is impaired because of the existence of various adulterants. In this study, genomic DNA (gDNA) suppression subtract...... hiện toàn bộ
Protein tyrosine phosphatase 1B inhibitory activity of Indonesian herbal medicines and constituents of Cinnamomum burmannii and Zingiber aromaticum
Journal of Natural Medicines - - 2013
Azis Saifudin, Shigetoshi Kadota, Yasuhiro Tezuka
Three new megastigmanes from the leaves of Annona muricata
Journal of Natural Medicines - Tập 66 - Trang 284-291 - 2011
Ayano Matsushige, Katsuyoshi Matsunami, Yaichiro Kotake, Hideaki Otsuka, Shigeru Ohta
Three new megastigmanes (1–3), named annoionols A and B (1, 2) and annoionoside (3), were isolated from the leaves of Annona muricata L. (Annonaceae) together with 14 known compounds (4–17). Among the known compounds, annoionol C (4) was isolated from a natural source for the first time. The structures of all compounds were elucidated by spectroscopic and chemical analyses.
Synthesis and stereochemical determination of an antiparasitic pseudo-aminal type monoterpene indole alkaloid
Journal of Natural Medicines - Tập 70 - Trang 302-317 - 2016
Yoshihiko Noguchi, Tomoyasu Hirose, Aki Ishiyama, Masato Iwatsuki, Kazuhiko Otoguro, Toshiaki Sunazuka, Satoshi Ōmura
5-Nor stemmadenine alkaloids, isolated from the genus Tabernaemontana, display a range of bioactivity. 16-Hydroxy-16,22-dihydroapparicine, the active component of an extract from the Tabernaemontana sp. (dichotoma, elegans, and divaricate), exhibited potent antimalarial activity, representing the first such report of the antimalarial property of 5-nor stemmadenine alkaloids. We, therefore, decided...... hiện toàn bộ
Protective effect of Pueraria tuberosa DC. embedded biscuit on cisplatin-induced nephrotoxicity in mice
Journal of Natural Medicines - - 2012
Yamini B. Tripathi, Santosh Nagwani, P. C. Mishra, Alok Jha, Shashi Pandey-Rai
In vitro and in vivo antiherpetic effects of (1R,2R)-1-(5′-methylful-3′-yl)propane-1,2,3-triol
Journal of Natural Medicines - Tập 70 - Trang 217-224 - 2016
Kohei Sasaki, Kyoko Hayashi, Yuji Matsuya, Kenji Sugimoto, Jung-Bum Lee, Fumiya Kurosaki, Toshimitsu Hayashi
In this study, we demonstrated the in vitro and in vivo antiherpetic activities of a stable furan derivative, (1R,2R)-1-(5′-methylful-3′-yl)propane-1,2,3-triol (MFPT), which had originally been isolated from Streptomyces sp. strain FV60. In the present study, we synthesized MFPT from (5-methylfuran-3-yl)methanol in 6 steps for use in the experiments. MFPT showed potent in vitro antiviral activitie...... hiện toàn bộ
Anti-inflammatory activities of Ophiopogonis Radix on hydrogen peroxide-induced cellular senescence of normal human dermal fibroblasts
Journal of Natural Medicines - Tập 72 Số 4 - Trang 905-914 - 2018
Yumi Kitahiro, Atsushi Koike, Aska Sonoki, Mei Muto, Kazuo Ozaki, Makio Shibano
Quantification of terpene trilactones in Ginkgo biloba with a 1H NMR method
Journal of Natural Medicines - Tập 72 - Trang 793-797 - 2018
Tingfu Liang, Takuya Miyakawa, Jinwei Yang, Tsutomu Ishikawa, Masaru Tanokura
Ginkgo biloba L. has been used as a herbal medicine in the traditional treatment of insufficient blood flow, memory deficits, and cerebral insufficiency. The terpene trilactone components, the bioactive agents of Ginkgo biloba L., have also been reported to exhibit useful functionality such as anti-inflammatory and neuroprotective effects. Therefore, in the present research, we attempted to analyz...... hiện toàn bộ
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