Gamma-enolase predicts lung damage in severe acute pancreatitis-induced acute lung injuryJournal of Molecular Histology - Tập 49 - Trang 347-356 - 2018
Lawrence Owusu, Caiming Xu, Hailong Chen, Geliang Liu, Guixin Zhang, Jinwen Zhang, Zhankai Tang, Zhongwei Sun, Xin Yi
Severe acute pancreatitis (SAP) associated acute lung injury (ALI) accounts for about 70% mortality of SAP patients. However, there are no precise biomarkers for the disease currently. Herein, we evaluated the potential of gamma-enolase (ENO2), against its universal isoform alpha-enolase (ENO1), as a marker of SAP–ALI in a rat model. Firstly, 16 male Sprague–Dawley rats were randomly divided into ...... hiện toàn bộ
Distribution, shape, and immunohistochemical characteristics of serotonin-immunoreactive neuroendocrine cells in the urethra and periurethral genital organs in miceJournal of Molecular Histology - Tập 52 - Trang 1205-1214 - 2021
Kei-ichiro Uemura, Tasuku Hiroshige, Kosuke Ueda, Keisuke Ohta, Tokumasa Hayashi, Shingo Hirashima, Tomonoshin Kanazawa, Makoto Nakiri, Tsukasa Igawa, Kei-ichiro Nakamura
The aim of this study is to clarify the disibution, shape, and immunohistochemical characteristics of serotonin-immunoreactive neuroendocrine cells (SIR-NECs) in mouse prostate and in the surrounding genital organs by histological and immunohistochemical analysis of the light microscopic serial sections of urethra. We collected lower urinary tracts from 13-week-old mice and observed the distributi...... hiện toàn bộ
Characterization of sinusoidal endothelial cells of the liver and bone marrow using an intravital lectin injection methodJournal of Molecular Histology - Tập 39 - Trang 471-479 - 2008
Ayako Nakamura-Ishizu, Shunichi Morikawa, Kazuhiko Shimizu, Taichi Ezaki
The vascular endothelia express a variety of structural and biological phenotypes. We used an intravital injection method of plant derived lectins (Lycopersicon esculentum lectin (LEL), Ricinus communis Agglutinin-I (RCA-I), Ulex europaeus Agglutinin-I (UEA-I) and Concanavalin A (ConA)) to elucidate the morphology and function of the sinusoidal endothelium of the liver and bone marrow. All four le...... hiện toàn bộ
High dose of TNF-α suppressed osteogenic differentiation of human dental pulp stem cells by activating the Wnt/β-catenin signalingJournal of Molecular Histology - Tập 46 - Trang 409-420 - 2015
Zhenjie Qin, Zhixiu Fang, Lei Zhao, Jing Chen, Yuanteng Li, Guangyun Liu
Dental pulp stem cells (DPSCs) were a clonogenic, highly proliferative cells capable of self-renewal and multi-lineage differentiation including chondrocytes, adipocytes, neural cells and osteoblasts, which make it an attractive choice for bone regeneration and repair of craniofacial defects. Recent studies showed that tumor necrosis factor α (TNF-α) may affect osteoclastogenesis and bone formatio...... hiện toàn bộ
Increased PELP1 expression in rat periodontal ligament tissue in response to estrogens treatmentJournal of Molecular Histology - Tập 44 - Trang 347-356 - 2013
Jing Wang, Qiang Zhu, Shujun Song, Jun Dong, Lixin Shi, Ran Tao, Yin Ding, Baofa Hong
Estrogens and their receptors are important factors involved in periodontal ligament (PDL) tissue health. As a regulator of estrogen receptors (ER), the proline-, glutamic acid-, and leucine-rich protein 1 (PELP1) may play a role in alveolar bone formation and PDL homeostasis. The aim of the present study was to observe PELP1 expression in rat PDL tissue during estrogen levels manipulations. Twent...... hiện toàn bộ
Lentiviral delivery of biglycan promotes proliferation and increases osteogenic potential of bone marrow-derived mesenchymal stem cells in vitroJournal of Molecular Histology - Tập 44 - Trang 423-431 - 2013
Bo Wu, Xu Ma, Damu Zhu, Ye Liu, Zhuqing Sun, Suyuan Liu, Bing Xue, Mingchang Du, Ximeng Yin
Mesenchymal stem cells (MSCs) are multipotent progenitor nonhematopoietic cells that have emerged as an attractive cell source for tissue engineering. Biglycan (BGN), an extracellular matrix component, has been reported to play a crucial role in bone formation. However, the role of BGN in MSCs remains unknown. Using lentiviral gene delivery, we sought to investigate the cellular effects of BGN on ...... hiện toàn bộ
Differential expression of ABC transporters (MDR1, MRP1, BCRP) in developing human embryosJournal of Molecular Histology - Tập 42 - Trang 567-574 - 2011
A. Konieczna, B. Erdösová, R. Lichnovská, M. Jandl, K. Čížková, J. Ehrmann
Three ABC transporters (MDR1, MRP1, BCRP), belonging to the family of multidrug resistance (MDR) proteins, play a crucial role in the protection mechanisms during embryogenesis and mediate drug resistance in cancer cells. The distribution of these transporters in the series of human embryonal/fetal intestine, liver and kidneys of various stages of intrauterine development (IUD) by indirect two-ste...... hiện toàn bộ
Disruption of tight junction structure contributes to secretory dysfunction in IgG4-related sialadenitisJournal of Molecular Histology - Tập 51 - Trang 33-46 - 2019
Sai-Nan Min, Li-Ling Wu, Yan-Yan Zhang, Wen-Xuan Zhu, Xin Cong, Guang-Yan Yu
IgG4-related sialadenitis (IgG4-RS) is a chronic fibro-inflammatory disease characterized by swelling of salivary glands and varying degrees of xerostomia. Tight junctions (TJs) play an essential role in maintaining secretory function by regulating the paracellular flow of ions and water. However, whether TJs are altered and contribute to the hyposecretion in IgG4-RS is not fully understood. Here,...... hiện toàn bộ
Canonical and non-canonical Wnt signaling control the regeneration of amputated rodent vibrissae folliclesJournal of Molecular Histology - Tập 47 - Trang 1-8 - 2016
Yan-Ping Yuan, Keng Huang, Yan-Min Xu, Xian-Cai Chen, Hai-Hong Li, Bo-Zhi Cai, Yang Liu, Huan Zhang, Yu Li, Chang-Min Lin
Although mammals are notoriously poor at regeneration compared with many lower-order species, the hair follicle, particular to mammals, is capable of regeneration following partial amputation. The detailed internal mechanism of this phenomenon is still unclear. Development and regrowth of the hair follicle depends on dermal-epidermal interaction within the hair follicle. Previous studies have show...... hiện toàn bộ