Journal of Medicinal Chemistry

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The [(Methyloxy)imino]methyl Moiety as a Bioisoster of Aryl. A Novel Class of Completely Aliphatic .beta.-Adrenergic Receptor Antagonists
Journal of Medicinal Chemistry - Tập 37 Số 10 - Trang 1518-1525 - 1994
Bruno Macchia, Aldo Balsamo, Maria Cristina Breschi, Grazia Chiellini, Marco Macchia, Adriano Martinelli, Claudia Martini, Claudia Nardini, Susanna Nencetti
More Lipophilic Dialkyldiamine-Based Diazeniumdiolates: Synthesis, Characterization, and Application in Preparing Thromboresistant Nitric Oxide Release Polymeric Coatings
Journal of Medicinal Chemistry - Tập 46 Số 24 - Trang 5153-5161 - 2003
Melissa M. Batchelor, Sylvie L. Reoma, Paul S. Fleser, Vijay K. Nuthakki, Rose E. Callahan, Charles J. Shanley, Jeffrey K. Politis, Jessica Elmore, Scott I. Merz, Mark E. Meyerhoff
PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease
Journal of Medicinal Chemistry - Tập 64 Số 1 - Trang 326-342 - 2021
Ariamala Gopalsamy, Ann Aulabaugh, Amey Barakat, Kevin Beaumont, Shawn Cabral, Daniel P. Canterbury, Agustin Casimiro‐Garcia, Jeanne S. Chang, Ming Z. Chen, Chulho Choi, Robert L. Dow, Olugbeminiyi Fadeyi, Xidong Feng, Scott P. France, Roger M. Howard, Jay M. Janz, J. Jasti, Reema Jasuja, Lyn H. Jones, Amanda King‐Ahmad, Kelly M. Knee, Jeffrey T. Kohrt, Chris Limberakis, Spiros Liras, Carlos A. Martínez, Kim F. McClure, Arjun Narayanan, Jatin Narula, Jonathan J. Novak, Thomas N. O’Connell, Mihir D. Parikh, David W. Piotrowski, Olga Plotnikova, Ralph P. Robinson, Parag V. Sahasrabudhe, Raman Sharma, Benjamin A. Thuma, Dipy M. Vasa, Liuqing Wei, Anne Wenzel, Jane M. Withka, Jun Xiao, Hatice G. Yayla
N-Benzyl/Aryl Substituted Tryptanthrin as Dual Inhibitors of Indoleamine 2,3-Dioxygenase and Tryptophan 2,3-Dioxygenase
Journal of Medicinal Chemistry - Tập 62 Số 20 - Trang 9161-9174 - 2019
Dan Yang, Shengnan Zhang, Xin Fang, Leilei Guo, Nan Hu, Guo Zhanling, Xishuai Li, Shuangshuang Yang, Jin Chao He, Chunxiang Kuang, Qing Yang
Novel Ester and Acid Derivatives of the 1,5-Diarylpyrrole Scaffold as Anti-Inflammatory and Analgesic Agents. Synthesis and in Vitro and in Vivo Biological Evaluation
Journal of Medicinal Chemistry - Tập 53 Số 2 - Trang 723-733 - 2010
Mariangela Biava, Giulio Cesare Porretta, Giovanna Poce, Claudio Battilocchio, Fabrizio Manetti, Maurizio Botta, Stefano Forli, Lidia Sautebin, Antonietta Rossi, Carlo Pergola, Carla Ghelardini, Nicoletta Galeotti, Francesco Makovec, Antonio Giordani, Paola Anzellotti, Paola Patrignani, Maurizio Anzini
Discovery, Synthesis, And Structure-Based Optimization of a Series of N-(tert-Butyl)-2-(N-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease
Journal of Medicinal Chemistry - Tập 56 Số 2 - Trang 534-546 - 2013
Jon Jacobs, Valerie Grum‐Tokars, Ya Zhou, Mark Turlington, S. Adrian Saldanha, Peter Chase, Aimee L. Eggler, Eric S. Dawson, Yahira M. Báez-Santos, Sakshi Tomar, Anna M. Mielech, Susan C. Baker, Craig W. Lindsley, Peter Hodder, Andrew D. Mesecar, Shaun R. Stauffer
Synthesis and .alpha.2-adrenoceptor antagonist activity of some disulfonamidobenzoquinolizines
Journal of Medicinal Chemistry - Tập 32 Số 1 - Trang 179-182 - 1989
Thomas J. Ward, Graham J. Warrellow, John A. Stirrup, N. Lattimer, K F Rhodes
Renin inhibitors. Dipeptide analogs of angiotensinogen utilizing a dihydroxyethylene transition-state mimic at the scissile bond to impart greater inhibitory potency
Journal of Medicinal Chemistry - Tập 31 Số 12 - Trang 2264-2276 - 1988
Jay R. Luly, Nwe Y. BaMaung, Jeff Soderquist, Anthony K. L. Fung, H. J. Stein, Hollis D. Kleinert, Patrick A. Marcotte, David A. Egan, Barbara A. Bopp
Renin inhibitors containing .psi.[CH2O] pseudopeptide inserts
Journal of Medicinal Chemistry - Tập 31 Số 3 - Trang 671-677 - 1988
Ruth E. Ten Brink, Donald T. Pals, Douglas W. Harris, Garland A. Johnson
The importance of residues 2 (arginine) and 6 (histidine) in high-affinity angiotensin II antagonists
Journal of Medicinal Chemistry - Tập 31 Số 4 - Trang 737-741 - 1988
James M. Samanen, E. Brandeis, D. Narindray, Wade J. Adams, T. Cash, Tobias O. Yellin, D. Regoli
Tổng số: 866   
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