A six-point map of the sex-chromosome ofNeurospora crassaJournal of Genetics - Tập 32 - Trang 243-256 - 1936
Carl C. Lindegren
Several new genes differentiating the growth habit ofNeurospora crassa were discovered. One of these,clump, was distinguished from the others by the fact that it had no effect onnormal and improved the vigour of the mutantgap, when carried in the same nucleus. The standardnormal stock which had been propagated asexually for several years was found to be heterokaryotic as result of mutations. The f...... hiện toàn bộ
Haldane, Waddington and recombinant inbred lines: extension of their work to any number of genesJournal of Genetics - Tập 96 - Trang 795-800 - 2017
Areejit Samal, Olivier C. Martin
In the early 1930s, J. B. S. Haldane and C. H. Waddington collaborated on the consequences of genetic linkage and inbreeding. One elegant mathematical genetics problem solved by them concerns recombinant inbred lines (RILs) produced via repeated self or brother–sister mating. In this classic contribution, Haldane and Waddington derived an analytical formula for the probabilities of 2-locus and 3-l...... hiện toàn bộ
The deviation from linkage equilibrium with multiple loci varying in a stepping-stone clineJournal of Genetics - Tập 66 - Trang 45-67 - 1987
Freddy Bugge Christiansen
The balance between the creation of associations between alleles at different loci by immigration and the convergence to linkage equilibrium due to the recombination process is studied in a theoretical model. The geographical structure of the model is a stepping-stone chain of populations linking two genetically constant source populations. The model assumes an arbitrary number of autosomal loci a...... hiện toàn bộ